SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3i1i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB6_0
(GRAMICIDIN A)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		3 / 3 TRP A  68
ALA A 350
VAL A 352
 None
 0.92A 1c4dA-3i1iA:
undetectable
1c4dB-3i1iA:
undetectable		 1c4dA-3i1iA:
2.85
1c4dB-3i1iA:
2.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D8C_A_SORA4000_0
(MALATE SYNTHASE G)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		3 / 3 GLN A 160
HIS A 287
PRO A 179
 None
 0.93A 1d8cA-3i1iA:
undetectable		 1d8cA-3i1iA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		5 / 11 ALA A  54
VAL A  85
GLY A  70
ILE A 355
ILE A  44
 None
 0.78A 1sdvB-3i1iA:
undetectable		 1sdvB-3i1iA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T3R_A_017A1200_2
(PROTEASE RETROPEPSIN)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		5 / 11 ALA A  54
VAL A  85
GLY A  70
ILE A 355
ILE A  44
 None
 0.91A 1t3rB-3i1iA:
undetectable		 1t3rB-3i1iA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		4 / 7 LEU A 366
ASP A  79
THR A  80
HIS A  53
 None
 1.00A 1v55C-3i1iA:
undetectable
1v55N-3i1iA:
undetectable
1v55P-3i1iA:
undetectable		 1v55C-3i1iA:
20.51
1v55N-3i1iA:
19.42
1v55P-3i1iA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		3 / 3 GLU A  29
THR A  30
LEU A 136
 None
 0.70A 1v8bC-3i1iA:
4.3		 1v8bC-3i1iA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_1
(PROTEASE)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		5 / 9 ALA A  54
VAL A  85
GLY A  70
ILE A 355
ILE A  44
 None
 0.91A 2q5kA-3i1iA:
undetectable		 2q5kA-3i1iA:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		4 / 8 ASP A  79
THR A  80
HIS A  53
LEU A 366
 None
 0.99A 3ablA-3i1iA:
undetectable
3ablC-3i1iA:
undetectable
3ablP-3i1iA:
undetectable		 3ablA-3i1iA:
19.42
3ablC-3i1iA:
20.51
3ablP-3i1iA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		4 / 8 LEU A 366
ASP A  79
THR A  80
HIS A  53
 None
 1.00A 3ablC-3i1iA:
undetectable
3ablN-3i1iA:
undetectable
3ablP-3i1iA:
undetectable		 3ablC-3i1iA:
20.51
3ablN-3i1iA:
19.42
3ablP-3i1iA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_2
(PROTEASE)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		5 / 9 ALA A  54
VAL A  85
GLY A  70
ILE A 355
ILE A  44
 None
 0.88A 3ekvB-3i1iA:
undetectable		 3ekvB-3i1iA:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_1
(GAG-POL POLYPROTEIN)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		5 / 12 ALA A  54
VAL A  85
GLY A  70
ILE A 355
ILE A  44
 None
 0.86A 3jw2A-3i1iA:
undetectable		 3jw2A-3i1iA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_2
(HIV-1 PROTEASE)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		5 / 11 ALA A  54
VAL A  85
GLY A  70
ILE A 355
ILE A  44
 None
 0.83A 3lzvB-3i1iA:
undetectable		 3lzvB-3i1iA:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_1
(PROTEASE)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		5 / 10 ALA A  54
VAL A  85
GLY A  70
ILE A 355
ILE A  44
 None
 0.82A 3nu6A-3i1iA:
undetectable		 3nu6A-3i1iA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_1
(PROTEASE)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		5 / 10 ALA A  54
VAL A  85
GLY A  70
ILE A 355
ILE A  44
 None
 0.85A 3nujA-3i1iA:
undetectable		 3nujA-3i1iA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3V_A_TOPA193_1
(DIHYDROFOLATE
REDUCTASE)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		4 / 5 ASP A 315
LEU A 316
ILE A 345
PHE A 233
 None
 1.07A 3s3vA-3i1iA:
undetectable		 3s3vA-3i1iA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFE_C_TMGC1_1
(SUCCINATE
DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR SUBUNIT,
MITOCHONDRIAL
SUCCINATE
DEHYDROGENASE
CYTOCHROME B560
SUBUNIT,
MITOCHONDRIAL)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		4 / 8 HIS A 146
ILE A  42
TRP A  68
ILE A 173
 None
 0.93A 3sfeB-3i1iA:
undetectable
3sfeC-3i1iA:
undetectable		 3sfeB-3i1iA:
21.50
3sfeC-3i1iA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_1
(ASPARTYL PROTEASE)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		5 / 11 ALA A  54
VAL A  85
GLY A  70
ILE A 355
ILE A  44
 None
 0.90A 4dqeA-3i1iA:
undetectable		 4dqeA-3i1iA:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_1
(ASPARTYL PROTEASE)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		5 / 12 ALA A  54
VAL A  85
GLY A  70
ILE A 355
ILE A  44
 None
 0.82A 4dqfA-3i1iA:
undetectable		 4dqfA-3i1iA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_1
(PROTEASE)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		5 / 11 ALA A  54
VAL A  85
GLY A  70
ILE A 355
ILE A  44
 None
 0.90A 4njtA-3i1iA:
undetectable		 4njtA-3i1iA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_1
(PROTEASE)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		5 / 11 ALA A  54
VAL A  85
GLY A  70
ILE A 355
ILE A  44
 None
 0.90A 4njtC-3i1iA:
undetectable		 4njtC-3i1iA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_2
(NUPC FAMILY PROTEIN)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		3 / 3 THR A 185
ASN A 221
PHE A 225
 None
 0.79A 4pd9A-3i1iA:
undetectable		 4pd9A-3i1iA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1W_A_017A104_2
(ASPARTYL PROTEASE)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		5 / 10 ALA A  54
VAL A  85
GLY A  70
ILE A 355
ILE A  44
 None
 0.88A 4q1wB-3i1iA:
undetectable		 4q1wB-3i1iA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		3 / 3 PRO A 166
MET A 168
TYR A 165
 None
None
GOL  A 504 ( 4.9A)
 1.03A 4qa2B-3i1iA:
undetectable		 4qa2B-3i1iA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_1
(HIV-1 PROTEASE)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		5 / 11 ALA A  54
VAL A  85
GLY A  70
ILE A 355
ILE A  44
 None
 0.85A 4rvjA-3i1iA:
undetectable		 4rvjA-3i1iA:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_1
(HIV-1 PROTEASE)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		5 / 11 ALA A  54
VAL A  85
GLY A  70
ILE A 355
ILE A  44
 None
 0.84A 4rvjC-3i1iA:
undetectable		 4rvjC-3i1iA:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALB_L_TIQL1210_2
(MEDI2452 LIGHT CHAIN)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		4 / 8 SER A  65
GLY A  56
ALA A  77
GLY A  73
 None
 0.82A 5albL-3i1iA:
undetectable		 5albL-3i1iA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		4 / 8 ASP A  79
THR A  80
HIS A  53
LEU A 366
 None
 0.94A 5b1bA-3i1iA:
undetectable
5b1bC-3i1iA:
undetectable
5b1bP-3i1iA:
undetectable		 5b1bA-3i1iA:
19.42
5b1bC-3i1iA:
20.51
5b1bP-3i1iA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		4 / 6 PHE A  48
SER A 152
ALA A 153
HIS A 348
 None
 1.20A 5dzkB-3i1iA:
2.2
5dzkP-3i1iA:
undetectable		 5dzkB-3i1iA:
20.63
5dzkP-3i1iA:
0.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		4 / 8 PHE A  48
SER A 152
ALA A 153
HIS A 348
 None
 1.21A 5dzkd-3i1iA:
undetectable
5dzkr-3i1iA:
undetectable		 5dzkd-3i1iA:
20.63
5dzkr-3i1iA:
0.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		4 / 8 PHE A  48
SER A 152
ALA A 153
HIS A 348
 None
 1.21A 5dzkF-3i1iA:
undetectable
5dzkT-3i1iA:
undetectable		 5dzkF-3i1iA:
20.63
5dzkT-3i1iA:
0.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_U_BEZU801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		4 / 6 PHE A  48
SER A 152
ALA A 153
HIS A 348
 None
 1.20A 5dzkg-3i1iA:
undetectable
5dzku-3i1iA:
undetectable		 5dzkg-3i1iA:
20.63
5dzku-3i1iA:
0.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		4 / 6 ASP A  89
ILE A  86
TYR A  31
TYR A  58
 None
 1.42A 5igyA-3i1iA:
undetectable		 5igyA-3i1iA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		4 / 8 LEU A 366
ASP A  79
THR A  80
HIS A  53
 None
 1.01A 5iy5C-3i1iA:
undetectable
5iy5N-3i1iA:
undetectable
5iy5P-3i1iA:
undetectable		 5iy5C-3i1iA:
20.77
5iy5N-3i1iA:
19.42
5iy5P-3i1iA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		3 / 3 GLY A  75
ASP A  79
ASN A  40
 None
 0.52A 5jglA-3i1iA:
2.4		 5jglA-3i1iA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		5 / 12 LYS A 361
ASN A 367
ALA A 147
VAL A 307
TYR A 336
 None
 1.28A 5kbwB-3i1iA:
undetectable		 5kbwB-3i1iA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJY_A_BEZA304_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		3 / 3 MET A 226
GLU A 258
ARG A 222
 None
 0.88A 5tjyA-3i1iA:
3.5		 5tjyA-3i1iA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJZ_A_BEZA302_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		3 / 3 MET A 226
GLU A 258
ARG A 222
 None
 0.97A 5tjzA-3i1iA:
3.5		 5tjzA-3i1iA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		4 / 8 ASP A  79
THR A  80
HIS A  53
LEU A 366
 None
 1.08A 5w97A-3i1iA:
undetectable
5w97C-3i1iA:
undetectable
5w97c-3i1iA:
undetectable		 5w97A-3i1iA:
19.42
5w97C-3i1iA:
20.51
5w97c-3i1iA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		4 / 7 LEU A 366
ASP A  79
THR A  80
HIS A  53
 None
 1.12A 5w97C-3i1iA:
undetectable
5w97a-3i1iA:
undetectable
5w97c-3i1iA:
undetectable		 5w97C-3i1iA:
20.51
5w97a-3i1iA:
19.42
5w97c-3i1iA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		4 / 8 ASP A  79
THR A  80
HIS A  53
LEU A 366
 None
 1.01A 5wauA-3i1iA:
undetectable
5wauC-3i1iA:
undetectable
5wauc-3i1iA:
undetectable		 5wauA-3i1iA:
19.42
5wauC-3i1iA:
20.51
5wauc-3i1iA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		4 / 7 LEU A 366
ASP A  79
THR A  80
HIS A  53
 None
 0.98A 5wauC-3i1iA:
undetectable
5waua-3i1iA:
undetectable
5wauc-3i1iA:
undetectable		 5wauC-3i1iA:
20.51
5waua-3i1iA:
19.42
5wauc-3i1iA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		4 / 8 ASP A  79
THR A  80
HIS A  53
LEU A 366
 None
 1.03A 5x19A-3i1iA:
undetectable
5x19C-3i1iA:
undetectable
5x19P-3i1iA:
undetectable		 5x19A-3i1iA:
19.42
5x19C-3i1iA:
20.51
5x19P-3i1iA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		4 / 7 ASP A  79
THR A  80
HIS A  53
LEU A 366
 None
 0.97A 5x1bA-3i1iA:
undetectable
5x1bC-3i1iA:
undetectable
5x1bP-3i1iA:
undetectable		 5x1bA-3i1iA:
19.42
5x1bC-3i1iA:
20.51
5x1bP-3i1iA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		4 / 7 ASP A  79
THR A  80
HIS A  53
LEU A 366
 None
 1.02A 5x1fA-3i1iA:
undetectable
5x1fC-3i1iA:
undetectable
5x1fP-3i1iA:
undetectable		 5x1fA-3i1iA:
19.42
5x1fC-3i1iA:
20.51
5x1fP-3i1iA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		4 / 7 ALA A 281
THR A 280
TYR A 279
PRO A 213
 None
 0.71A 6cduA-3i1iA:
undetectable
6cduE-3i1iA:
undetectable		 6cduA-3i1iA:
22.60
6cduE-3i1iA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_E_EY4E500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		5 / 8 ILE A 269
PRO A 213
ALA A 281
THR A 280
TYR A 279
 None
 1.42A 6cduD-3i1iA:
undetectable
6cduE-3i1iA:
undetectable		 6cduD-3i1iA:
22.60
6cduE-3i1iA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_H_EY4H500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		4 / 7 PRO A 213
ALA A 281
THR A 280
TYR A 279
 None
 0.69A 6cduH-3i1iA:
undetectable
6cduI-3i1iA:
undetectable		 6cduH-3i1iA:
22.60
6cduI-3i1iA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_0
(HIV-1 PROTEASE)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		5 / 10 ALA A  54
VAL A  85
GLY A  70
ILE A 355
ILE A  44
 None
 0.89A 6dj2A-3i1iA:
undetectable		 6dj2A-3i1iA:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		4 / 8 LEU A 366
ASP A  79
THR A  80
HIS A  53
 None
 1.02A 6nknC-3i1iA:
undetectable
6nknN-3i1iA:
undetectable
6nknP-3i1iA:
undetectable		 6nknC-3i1iA:
20.51
6nknN-3i1iA:
19.42
6nknP-3i1iA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3i1i HOMOSERINE
O-ACETYLTRANSFERASE
(Bacillus
anthracis) 		4 / 7 ASP A  79
THR A  80
HIS A  53
LEU A 366
 None
 0.94A 6nmfA-3i1iA:
undetectable
6nmfC-3i1iA:
undetectable
6nmfP-3i1iA:
undetectable		 6nmfA-3i1iA:
19.42
6nmfC-3i1iA:
20.51
6nmfP-3i1iA:
20.51