SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3i1j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_F_CCSF47_0
(GLUTATHIONE
S-TRANSFERASE)		 3i1j OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 5 THR A 236
LEU A 230
GLY A 232
TYR A 229
 None
 1.07A 1gtiF-3i1jA:
undetectable		 1gtiF-3i1jA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_2
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3i1j OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 3 LEU A  17
HIS A  99
ILE A 148
 None
 0.59A 1s9pB-3i1jA:
undetectable		 1s9pB-3i1jA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3i1j OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 VAL A 190
PHE A 150
HIS A  99
THR A 133
 None
 1.16A 2f78A-3i1jA:
undetectable		 2f78A-3i1jA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1004_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3i1j OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 VAL A 190
PHE A 150
HIS A  99
THR A 133
 None
 1.17A 2f78B-3i1jA:
undetectable		 2f78B-3i1jA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1376_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3i1j OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 TYR A  33
GLY A  20
ALA A  21
LEU A  42
 None
EDO  A 252 (-3.3A)
None
None
 0.91A 2wekB-3i1jA:
8.2		 2wekB-3i1jA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_2
(ADENOSINE KINASE)		 3i1j OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 5 SER A 153
ILE A  25
TYR A 166
GLY A 198
 ACT  A 248 (-2.4A)
None
EDO  A 249 (-4.4A)
None
 0.90A 3uboB-3i1jA:
6.3		 3uboB-3i1jA:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3i1j OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 5 LEU A 137
PRO A 138
LEU A 140
ILE A 148
 None
 0.88A 4klrA-3i1jA:
2.9		 4klrA-3i1jA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 3i1j OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 3 PRO A 138
LEU A 139
HIS A  89
 None
 0.66A 4pevA-3i1jA:
4.7		 4pevA-3i1jA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 3i1j OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 ALA A  30
GLY A  20
GLY A  26
GLY A  24
LEU A  43
 None
EDO  A 252 (-3.3A)
None
CL  A 255 ( 3.8A)
EDO  A 252 (-4.5A)
 0.82A 5c0oH-3i1jA:
6.9		 5c0oH-3i1jA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_G_SAMG501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3i1j OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 11 LEU A 180
GLU A 174
GLY A 175
LEU A 184
ALA A 192
 None
 1.00A 5o96G-3i1jA:
2.3		 5o96G-3i1jA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA613_1
(SERUM ALBUMIN)		 3i1j OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 8 ALA A 172
SER A 153
THR A 151
GLY A 167
 None
ACT  A 248 (-2.4A)
None
None
 0.95A 5v0vA-3i1jA:
undetectable		 5v0vA-3i1jA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_0
(REGULATORY PROTEIN
TETR)		 3i1j OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 ALA A  84
LEU A 140
VAL A  41
TYR A  33
THR A  19
 None
 1.14A 5vlmD-3i1jA:
undetectable		 5vlmD-3i1jA:
23.46