SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3i1l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VIF_A_FOLA1_0
(DIHYDROFOLATE
REDUCTASE)		 3i1l HEMAGGLUTININ-ESTERA
SE PROTEIN
(Porcine
torovirus) 		3 / 3 GLN A 179
ILE A 274
TYR A 275
 NAG  A5155 (-4.0A)
None
None
 0.59A 1vifA-3i1lA:
undetectable		 1vifA-3i1lA:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_C_CHDC3_0
(LIVER
CARBOXYLESTERASE 1)		 3i1l HEMAGGLUTININ-ESTERA
SE PROTEIN
(Porcine
torovirus) 		4 / 6 LEU A 349
LEU A  65
PRO A  33
VAL A 102
 None
 1.18A 2dqyC-3i1lA:
undetectable		 2dqyC-3i1lA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_B_BEZB1352_0
(D-AMINO-ACID OXIDASE)		 3i1l HEMAGGLUTININ-ESTERA
SE PROTEIN
(Porcine
torovirus) 		4 / 6 LEU A 136
TYR A 133
TYR A 137
GLY A 106
 None
 0.87A 2du8B-3i1lA:
undetectable		 2du8B-3i1lA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMB_A_PXBA692_1
(LACTOTRANSFERRIN)		 3i1l HEMAGGLUTININ-ESTERA
SE PROTEIN
(Porcine
torovirus) 		3 / 3 PRO A 276
GLU A 233
TYR A 232
 None
 0.67A 2zmbA-3i1lA:
undetectable		 2zmbA-3i1lA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF3_A_PAUA314_0
(PANTOTHENATE KINASE)		 3i1l HEMAGGLUTININ-ESTERA
SE PROTEIN
(Porcine
torovirus) 		4 / 6 ARG A 161
MET A 221
PHE A 219
PHE A 228
 SIO  A1001 (-3.4A)
SIO  A1001 (-3.7A)
SIO  A1001 (-3.5A)
None
 1.48A 3af3A-3i1lA:
undetectable		 3af3A-3i1lA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGG_A_CHDA211_0
(CMER)		 3i1l HEMAGGLUTININ-ESTERA
SE PROTEIN
(Porcine
torovirus) 		4 / 7 CYH A  41
PHE A  43
SER A  70
TYR A  94
 None
 1.38A 3hggA-3i1lA:
undetectable		 3hggA-3i1lA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAK_A_EV1A415_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3i1l HEMAGGLUTININ-ESTERA
SE PROTEIN
(Porcine
torovirus) 		5 / 9 TYR A 238
PHE A 237
MET A 259
PHE A 211
ILE A 274
 None
 1.49A 3iakA-3i1lA:
undetectable		 3iakA-3i1lA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB0_A_DIFA701_1
(LACTOTRANSFERRIN)		 3i1l HEMAGGLUTININ-ESTERA
SE PROTEIN
(Porcine
torovirus) 		4 / 4 PRO A 227
TYR A 242
GLY A 245
THR A 246
 None
 1.47A 3ib0A-3i1lA:
undetectable		 3ib0A-3i1lA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W37_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 3i1l HEMAGGLUTININ-ESTERA
SE PROTEIN
(Porcine
torovirus) 		5 / 12 ASP A  60
ALA A  46
ASN A  52
ILE A 308
ASP A  45
 None
ACY  A2001 (-3.2A)
None
None
ACY  A2001 (-4.1A)
 1.09A 3w37A-3i1lA:
undetectable		 3w37A-3i1lA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEL_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 3i1l HEMAGGLUTININ-ESTERA
SE PROTEIN
(Porcine
torovirus) 		5 / 12 ASP A  60
ALA A  46
ASN A  52
ILE A 308
ASP A  45
 None
ACY  A2001 (-3.2A)
None
None
ACY  A2001 (-4.1A)
 1.13A 3welA-3i1lA:
undetectable		 3welA-3i1lA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1002_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 3i1l HEMAGGLUTININ-ESTERA
SE PROTEIN
(Porcine
torovirus) 		3 / 3 ASN A 128
TRP A 125
ASP A 255
 None
 0.90A 4a7tA-3i1lA:
undetectable
4a7tF-3i1lA:
undetectable		 4a7tA-3i1lA:
18.41
4a7tF-3i1lA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1Y_A_RBFA1176_1
(PUTATIVE PROTEASE I)		 3i1l HEMAGGLUTININ-ESTERA
SE PROTEIN
(Porcine
torovirus) 		4 / 8 ASN A 177
TRP A  83
GLN A 179
THR A 164
 None
None
NAG  A5155 (-4.0A)
SIO  A1001 (-4.3A)
 1.36A 4d1yA-3i1lA:
undetectable
4d1yB-3i1lA:
undetectable		 4d1yA-3i1lA:
16.93
4d1yB-3i1lA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_G_377G401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3i1l HEMAGGLUTININ-ESTERA
SE PROTEIN
(Porcine
torovirus) 		4 / 6 TYR A 280
GLU A 105
TYR A 133
PHE A 103
 None
 1.33A 4twdF-3i1lA:
undetectable
4twdG-3i1lA:
undetectable		 4twdF-3i1lA:
20.31
4twdG-3i1lA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_J_377J401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3i1l HEMAGGLUTININ-ESTERA
SE PROTEIN
(Porcine
torovirus) 		4 / 6 ASN A 177
TYR A 256
LEU A 208
PHE A 132
 None
 1.19A 4twdI-3i1lA:
undetectable
4twdJ-3i1lA:
undetectable		 4twdI-3i1lA:
20.31
4twdJ-3i1lA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_0
(PEPTIDYLPROLYL
ISOMERASE)		 3i1l HEMAGGLUTININ-ESTERA
SE PROTEIN
(Porcine
torovirus) 		4 / 4 ASP A  49
ILE A  61
PRO A  62
LEU A  59
 None
 0.86A 6mkeB-3i1lA:
undetectable		 6mkeB-3i1lA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_0
(PEPTIDYLPROLYL
ISOMERASE)		 3i1l HEMAGGLUTININ-ESTERA
SE PROTEIN
(Porcine
torovirus) 		4 / 4 ASP A  49
ILE A  61
PRO A  62
LEU A  59
 None
 0.85A 6mkeA-3i1lA:
undetectable		 6mkeA-3i1lA:
12.50