SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3i24'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_1
(PROTEASE)		 3i24 HIT FAMILY HYDROLASE
(Aliivibrio
fischeri) 		5 / 9 LEU A   9
ILE A  80
PRO A  39
VAL A  38
ILE A  36
 None
None
NA  A 157 (-4.1A)
NA  A 157 ( 4.7A)
None
 1.16A 2r5qA-3i24A:
undetectable		 2r5qA-3i24A:
25.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_1
(PROTEASE)		 3i24 HIT FAMILY HYDROLASE
(Aliivibrio
fischeri) 		5 / 9 LEU A   9
ILE A  80
PRO A  39
VAL A  38
ILE A  36
 None
None
NA  A 157 (-4.1A)
NA  A 157 ( 4.7A)
None
 1.16A 2r5qC-3i24A:
undetectable		 2r5qC-3i24A:
25.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P73_A_ACTA275_0
(MHC RFP-Y CLASS I
ALPHA CHAIN)		 3i24 HIT FAMILY HYDROLASE
(Aliivibrio
fischeri) 		3 / 3 ILE A  14
VAL A 126
ARG A 130
 None
 0.35A 3p73A-3i24A:
undetectable		 3p73A-3i24A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_A_SAMA601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 3i24 HIT FAMILY HYDROLASE
(Aliivibrio
fischeri) 		4 / 5 PHE A  58
THR A  51
GLU A  61
ASN A  18
 None
 1.30A 5ybbA-3i24A:
undetectable		 5ybbA-3i24A:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3i24 HIT FAMILY HYDROLASE
(Aliivibrio
fischeri) 		5 / 12 ILE A  80
ALA A  66
ILE A  59
ILE A  47
LEU A  37
 None
NA  A 155 ( 4.1A)
None
NA  A 156 ( 3.9A)
None
 1.08A 6a5zD-3i24A:
undetectable		 6a5zD-3i24A:
19.57