SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3i27'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_C_H4BC1002_1
(HYPOTHETICAL PROTEIN
PH0634)		 3i27 HEMAGGLUTININ-ESTERA
SE
(Bovine
torovirus) 		4 / 6 TYR A 248
ASP A 247
THR A 121
GLU A 118
 None
 1.22A 2dttB-3i27A:
undetectable
2dttC-3i27A:
undetectable		 2dttB-3i27A:
12.57
2dttC-3i27A:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_B_BEZB1352_0
(D-AMINO-ACID OXIDASE)		 3i27 HEMAGGLUTININ-ESTERA
SE
(Bovine
torovirus) 		4 / 6 LEU A 127
TYR A 124
TYR A 128
GLY A  97
 None
 0.89A 2du8B-3i27A:
undetectable		 2du8B-3i27A:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 3i27 HEMAGGLUTININ-ESTERA
SE
(Bovine
torovirus) 		4 / 6 PHE A 181
LEU A 249
VAL A 197
VAL A 266
 None
 1.20A 2zawA-3i27A:
undetectable		 2zawA-3i27A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3i27 HEMAGGLUTININ-ESTERA
SE
(Bovine
torovirus) 		3 / 3 LEU A 148
PRO A 149
LEU A 151
 None
 0.54A 3hcrA-3i27A:
undetectable		 3hcrA-3i27A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 3i27 HEMAGGLUTININ-ESTERA
SE
(Bovine
torovirus) 		4 / 8 MET A  48
SER A 324
LEU A  50
ASP A  51
 NAG  A5157 ( 3.8A)
None
None
None
 1.08A 3lsfH-3i27A:
undetectable		 3lsfH-3i27A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_B_377B401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3i27 HEMAGGLUTININ-ESTERA
SE
(Bovine
torovirus) 		4 / 5 TYR A 272
GLU A  96
TYR A 124
PHE A  94
 None
 1.29A 4twdA-3i27A:
0.0
4twdB-3i27A:
undetectable		 4twdA-3i27A:
20.95
4twdB-3i27A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_G_377G401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3i27 HEMAGGLUTININ-ESTERA
SE
(Bovine
torovirus) 		4 / 6 TYR A 272
GLU A  96
TYR A 124
PHE A  94
 None
 1.32A 4twdF-3i27A:
undetectable
4twdG-3i27A:
undetectable		 4twdF-3i27A:
20.95
4twdG-3i27A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_J_377J401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3i27 HEMAGGLUTININ-ESTERA
SE
(Bovine
torovirus) 		4 / 6 ASN A 165
TYR A 248
LEU A 196
PHE A 123
 None
 1.31A 4twdI-3i27A:
undetectable
4twdJ-3i27A:
undetectable		 4twdI-3i27A:
20.95
4twdJ-3i27A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YBN_A_ACTA303_0
(FLAVIN-NUCLEOTIDE-BI
NDING PROTEIN)		 3i27 HEMAGGLUTININ-ESTERA
SE
(Bovine
torovirus) 		3 / 3 VAL A 283
TYR A 128
ALA A 131
 None
 0.56A 4ybnA-3i27A:
undetectable		 4ybnA-3i27A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3i27 HEMAGGLUTININ-ESTERA
SE
(Bovine
torovirus) 		4 / 6 VAL A  81
SER A  37
ILE A  52
PHE A  60
 None
 1.05A 5jw1B-3i27A:
undetectable		 5jw1B-3i27A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3i27 HEMAGGLUTININ-ESTERA
SE
(Bovine
torovirus) 		3 / 3 TYR A 248
ARG A 122
THR A 121
 None
 1.02A 5z84J-3i27A:
undetectable		 5z84J-3i27A:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3i27 HEMAGGLUTININ-ESTERA
SE
(Bovine
torovirus) 		3 / 3 TYR A 248
ARG A 122
THR A 125
 None
 0.81A 5z84J-3i27A:
undetectable		 5z84J-3i27A:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_E_EY4E500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3i27 HEMAGGLUTININ-ESTERA
SE
(Bovine
torovirus) 		5 / 8 ILE A 310
GLN A 284
VAL A 283
ALA A 131
THR A 133
 None
 1.39A 6cduD-3i27A:
undetectable
6cduE-3i27A:
undetectable		 6cduD-3i27A:
21.86
6cduE-3i27A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_0
(PEPTIDYLPROLYL
ISOMERASE)		 3i27 HEMAGGLUTININ-ESTERA
SE
(Bovine
torovirus) 		4 / 4 ASP A  40
ILE A  52
PRO A  53
LEU A  50
 None
 0.85A 6mkeB-3i27A:
undetectable		 6mkeB-3i27A:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_0
(PEPTIDYLPROLYL
ISOMERASE)		 3i27 HEMAGGLUTININ-ESTERA
SE
(Bovine
torovirus) 		4 / 4 ASP A  40
ILE A  52
PRO A  53
LEU A  50
 None
 0.83A 6mkeA-3i27A:
undetectable		 6mkeA-3i27A:
12.14