SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3i2w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3i2w SYNDAPIN
(Drosophila
melanogaster) 		3 / 3 VAL A  95
LYS A  98
HIS A 250
 None
 0.89A 3elzA-3i2wA:
undetectable		 3elzA-3i2wA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ202_1
(PROTEIN S100-A4)		 3i2w SYNDAPIN
(Drosophila
melanogaster) 		5 / 11 LEU A 103
ASP A 106
LEU A 253
SER A 251
ILE A  99
 None
 1.23A 3ko0A-3i2wA:
undetectable
3ko0B-3i2wA:
undetectable
3ko0I-3i2wA:
undetectable
3ko0J-3i2wA:
undetectable		 3ko0A-3i2wA:
15.99
3ko0B-3i2wA:
15.99
3ko0I-3i2wA:
15.99
3ko0J-3i2wA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP202_1
(PROTEIN S100-A4)		 3i2w SYNDAPIN
(Drosophila
melanogaster) 		5 / 12 LEU A 103
ASP A 106
LEU A 253
SER A 251
ILE A  99
 None
 1.23A 3ko0M-3i2wA:
undetectable
3ko0N-3i2wA:
undetectable
3ko0O-3i2wA:
undetectable
3ko0P-3i2wA:
undetectable		 3ko0M-3i2wA:
15.99
3ko0N-3i2wA:
15.99
3ko0O-3i2wA:
15.99
3ko0P-3i2wA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_C_CGEC501_1
(CYTOCHROME P450 2B4)		 3i2w SYNDAPIN
(Drosophila
melanogaster) 		5 / 9 PHE A 241
ILE A 111
PHE A 242
VAL A 249
VAL A 107
 None
 1.25A 3me6C-3i2wA:
undetectable		 3me6C-3i2wA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_H_SAMH301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3i2w SYNDAPIN
(Drosophila
melanogaster) 		5 / 12 ASP A 223
ALA A 139
ASP A 131
LYS A 127
SER A 226
 None
 1.39A 5hfjH-3i2wA:
undetectable		 5hfjH-3i2wA:
23.12