SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3i3a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_RALB600_1
(ESTROGEN RECEPTOR)		 3i3a ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Leptospira
interrogans) 		5 / 12 ALA A 134
LEU A 136
LEU A 169
LEU A 142
LEU A 124
 None
 0.98A 1errB-3i3aA:
undetectable		 1errB-3i3aA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_RALB600_1
(ESTROGEN RECEPTOR)		 3i3a ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Leptospira
interrogans) 		5 / 12 THR A 131
ALA A 134
LEU A 136
LEU A 142
LEU A 124
 None
 1.06A 1errB-3i3aA:
undetectable		 1errB-3i3aA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_2
(HIV-II PROTEASE)		 3i3a ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Leptospira
interrogans) 		5 / 9 ALA A  61
ILE A  94
ILE A  87
ILE A  51
ILE A  63
 None
 0.91A 1hshB-3i3aA:
undetectable		 1hshB-3i3aA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1499_1
(CYTOCHROME P450 3A4)		 3i3a ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Leptospira
interrogans) 		4 / 7 SER A  49
PHE A  88
ILE A  45
GLY A 119
 None
None
None
S2N  A 260 ( 3.8A)
 1.02A 2v0mC-3i3aA:
undetectable		 2v0mC-3i3aA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEY_B_EV1B1771_1
(CAMP AND
CAMP-INHIBITED CGMP
3', 5'-CYCLIC
PHOSPHODIESTERASE)		 3i3a ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Leptospira
interrogans) 		4 / 8 VAL A 118
ILE A  63
PHE A  57
PHE A 112
 None
 0.96A 2weyB-3i3aA:
undetectable		 2weyB-3i3aA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_B_ACTB1463_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 3i3a ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Leptospira
interrogans) 		4 / 7 VAL A  19
ILE A  33
GLY A  36
THR A  37
 None
 0.55A 2xrzB-3i3aA:
undetectable		 2xrzB-3i3aA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDI_A_SAMA601_0
(METHYLTRANSFERASE)		 3i3a ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Leptospira
interrogans) 		5 / 12 PHE A  57
GLU A  28
ILE A  27
ALA A  47
ILE A  33
 None
 1.07A 3ndiA-3i3aA:
undetectable		 3ndiA-3i3aA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_1
(ADENOSINE KINASE,
PUTATIVE)		 3i3a ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Leptospira
interrogans) 		5 / 12 ILE A 106
GLY A 138
GLY A 119
LEU A 130
GLY A  97
 None
S2N  A 260 (-3.8A)
S2N  A 260 ( 3.8A)
None
None
 1.01A 3uq6A-3i3aA:
undetectable		 3uq6A-3i3aA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 3i3a ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Leptospira
interrogans) 		5 / 12 ILE A 106
GLY A 138
GLY A 119
LEU A 130
GLY A  97
 None
S2N  A 260 (-3.8A)
S2N  A 260 ( 3.8A)
None
None
 1.01A 3vasA-3i3aA:
undetectable		 3vasA-3i3aA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3i3a ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Leptospira
interrogans) 		4 / 7 THR A 256
VAL A 216
SER A 180
ASP A 229
 None
 1.37A 4iarA-3i3aA:
undetectable		 4iarA-3i3aA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB307_1
(CHITOSANASE)		 3i3a ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Leptospira
interrogans) 		4 / 7 THR A 104
GLY A  97
THR A  80
HIS A 117
 None
None
None
S2N  A 260 (-3.9A)
 0.92A 4qwpB-3i3aA:
undetectable		 4qwpB-3i3aA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_A_Z80A401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3i3a ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Leptospira
interrogans) 		5 / 11 ILE A  39
ILE A  45
VAL A  21
ILE A   9
ALA A  13
 None
 1.01A 5lg3A-3i3aA:
undetectable		 5lg3A-3i3aA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_E_Z80E401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3i3a ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Leptospira
interrogans) 		5 / 12 ILE A  39
ILE A  45
VAL A  21
ILE A   9
ALA A  13
 None
 1.02A 5lg3E-3i3aA:
undetectable		 5lg3E-3i3aA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 3i3a ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Leptospira
interrogans) 		5 / 12 ILE A 106
THR A  37
VAL A  19
SER A  32
VAL A  31
 None
 1.20A 6bzoC-3i3aA:
undetectable		 6bzoC-3i3aA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F8C_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 3i3a ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Leptospira
interrogans) 		4 / 6 SER A 102
GLY A  97
ILE A  94
PHE A  88
 None
 0.81A 6f8cA-3i3aA:
undetectable		 6f8cA-3i3aA:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_F_FFOF403_0
(THYMIDYLATE SYNTHASE)		 3i3a ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Leptospira
interrogans) 		5 / 11 PHE A 147
ASN A  86
LEU A 142
GLY A 143
ASN A 144
 None
 1.25A 6r2eF-3i3aA:
undetectable		 6r2eF-3i3aA:
20.91