SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3i3g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QCA_A_FUAA221_1
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3i3g N-ACETYLTRANSFERASE
(Trypanosoma
brucei) 		4 / 7 PHE A 136
SER A 124
PHE A 130
LEU A  69
 None
 0.93A 1qcaA-3i3gA:
undetectable		 1qcaA-3i3gA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_B_HSMB402_1
(NITROPHORIN 1)		 3i3g N-ACETYLTRANSFERASE
(Trypanosoma
brucei) 		4 / 5 ASP A  16
GLU A   8
THR A  52
LEU A  12
 None
 1.12A 1u18B-3i3gA:
undetectable		 1u18B-3i3gA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJ8_C_SPMC500_1
(DIAMINE
ACETYLTRANSFERASE 1)		 3i3g N-ACETYLTRANSFERASE
(Trypanosoma
brucei) 		4 / 6 LEU A 107
ASP A  87
LEU A  24
HIS A  20
 None
 1.18A 3bj8C-3i3gA:
14.5
3bj8D-3i3gA:
14.9		 3bj8C-3i3gA:
22.91
3bj8D-3i3gA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3i3g N-ACETYLTRANSFERASE
(Trypanosoma
brucei) 		3 / 3 SER A  19
ASP A  16
ASP A  91
 None
 0.93A 3iv6C-3i3gA:
undetectable		 3iv6C-3i3gA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_A_HISA302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 3i3g N-ACETYLTRANSFERASE
(Trypanosoma
brucei) 		5 / 10 GLY A  65
THR A  52
VAL A  89
HIS A  20
LEU A  12
 None
 0.99A 4yb6A-3i3gA:
undetectable
4yb6E-3i3gA:
undetectable		 4yb6A-3i3gA:
21.23
4yb6E-3i3gA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_B_HISB302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 3i3g N-ACETYLTRANSFERASE
(Trypanosoma
brucei) 		5 / 10 GLY A  65
THR A  52
VAL A  89
HIS A  20
LEU A  12
 None
 0.99A 4yb6B-3i3gA:
undetectable
4yb6C-3i3gA:
undetectable		 4yb6B-3i3gA:
21.23
4yb6C-3i3gA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_C_HISC302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 3i3g N-ACETYLTRANSFERASE
(Trypanosoma
brucei) 		5 / 10 GLY A  65
THR A  52
VAL A  89
HIS A  20
LEU A  12
 None
 0.98A 4yb6C-3i3gA:
undetectable
4yb6F-3i3gA:
undetectable		 4yb6C-3i3gA:
21.23
4yb6F-3i3gA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_D_HISD302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 3i3g N-ACETYLTRANSFERASE
(Trypanosoma
brucei) 		5 / 10 HIS A  20
LEU A  12
GLY A  65
THR A  52
VAL A  89
 None
 0.99A 4yb6A-3i3gA:
undetectable
4yb6D-3i3gA:
undetectable		 4yb6A-3i3gA:
21.23
4yb6D-3i3gA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_E_HISE302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 3i3g N-ACETYLTRANSFERASE
(Trypanosoma
brucei) 		5 / 10 HIS A  20
LEU A  12
GLY A  65
THR A  52
VAL A  89
 None
 0.98A 4yb6D-3i3gA:
undetectable
4yb6E-3i3gA:
undetectable		 4yb6D-3i3gA:
21.23
4yb6E-3i3gA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_F_HISF302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 3i3g N-ACETYLTRANSFERASE
(Trypanosoma
brucei) 		5 / 10 HIS A  20
LEU A  12
GLY A  65
THR A  52
VAL A  89
 None
 0.98A 4yb6B-3i3gA:
undetectable
4yb6F-3i3gA:
undetectable		 4yb6B-3i3gA:
21.23
4yb6F-3i3gA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11803_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
EL18)		 3i3g N-ACETYLTRANSFERASE
(Trypanosoma
brucei) 		3 / 3 SER A 127
LYS A 126
SER A 124
 None
 0.80A 6az3P-3i3gA:
undetectable		 6az3P-3i3gA:
19.42