SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3i3n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA802_1
(TRANSPORTER)		 3i3n KELCH-LIKE PROTEIN
11
(Homo
sapiens) 		4 / 7 ARG A 229
PHE A 232
ILE A 228
PHE A 241
 None
 1.04A 2qb4A-3i3nA:
undetectable		 2qb4A-3i3nA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA802_1
(TRANSPORTER)		 3i3n KELCH-LIKE PROTEIN
11
(Homo
sapiens) 		4 / 6 ARG A 229
PHE A 232
ILE A 228
PHE A 241
 None
 1.03A 2qeiA-3i3nA:
undetectable		 2qeiA-3i3nA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_B_DX2B271_1
(PTERIDINE REDUCTASE
1)		 3i3n KELCH-LIKE PROTEIN
11
(Homo
sapiens) 		4 / 8 SER A 144
TYR A 215
LEU A 244
PRO A 245
 None
 1.20A 3jq7B-3i3nA:
undetectable		 3jq7B-3i3nA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_2
(PROTEASE)		 3i3n KELCH-LIKE PROTEIN
11
(Homo
sapiens) 		4 / 6 ILE A  96
PRO A 124
ASP A 181
VAL A 154
 None
 0.98A 3n3iA-3i3nA:
undetectable		 3n3iA-3i3nA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 3i3n KELCH-LIKE PROTEIN
11
(Homo
sapiens) 		5 / 10 LEU A 248
ILE A 249
LEU A 244
LEU A 266
PHE A 241
 None
 1.05A 4odoA-3i3nA:
undetectable		 4odoA-3i3nA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 3i3n KELCH-LIKE PROTEIN
11
(Homo
sapiens) 		5 / 10 LEU A 248
ILE A 249
LEU A 244
LEU A 266
PHE A 241
 None
 1.07A 4odoB-3i3nA:
undetectable		 4odoB-3i3nA:
17.82