SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3i4f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3i4f 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Bacillus
thuringiensis) 		4 / 7 VAL A 161
GLY A 170
THR A 272
ILE A 172
 None
 0.86A 1gtnC-3i4fA:
undetectable
1gtnD-3i4fA:
undetectable		 1gtnC-3i4fA:
13.41
1gtnD-3i4fA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_B_ANWB99_0
(PROTEIN S100-A13)		 3i4f 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Bacillus
thuringiensis) 		4 / 8 MET A 111
ALA A 110
VAL A  93
THR A  44
 None
 1.23A 2kotB-3i4fA:
undetectable		 2kotB-3i4fA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_B_FOLB703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3i4f 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Bacillus
thuringiensis) 		5 / 10 VAL A 220
PHE A 262
SER A 261
VAL A 278
THR A 274
 None
 1.46A 4eilB-3i4fA:
undetectable		 4eilB-3i4fA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_F_CAMF502_0
(CAMPHOR
5-MONOOXYGENASE)		 3i4f 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Bacillus
thuringiensis) 		4 / 4 TYR A 175
THR A  44
VAL A 153
ILE A 173
 None
 1.42A 4jx1F-3i4fA:
undetectable		 4jx1F-3i4fA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_1
(ADENOSINE KINASE)		 3i4f 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Bacillus
thuringiensis) 		5 / 12 ASP A 255
LEU A 240
GLY A 253
ALA A 237
GLY A 223
 None
 1.13A 4n09A-3i4fA:
7.8		 4n09A-3i4fA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3i4f 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Bacillus
thuringiensis) 		4 / 6 ASP A 269
ALA A 211
THR A 216
THR A 272
 None
 1.24A 4z4iA-3i4fA:
3.6		 4z4iA-3i4fA:
14.85