SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3i4q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3i4q APC40078
(Oleispira
antarctica) 		5 / 12 ALA A 108
PRO A  90
VAL A 109
GLN A 129
ASP A 123
 None
 1.29A 2v95A-3i4qA:
undetectable		 2v95A-3i4qA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3i4q APC40078
(Oleispira
antarctica) 		4 / 8 ILE A 166
PRO A  13
VAL A  93
GLY A  92
 None
 0.83A 3em0B-3i4qA:
undetectable		 3em0B-3i4qA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA201_1
(PROTEIN S100-A4)		 3i4q APC40078
(Oleispira
antarctica) 		5 / 9 GLY A  83
ILE A  29
PHE A  51
PHE A 138
GLY A  57
 None
 1.11A 3ko0A-3i4qA:
undetectable
3ko0C-3i4qA:
undetectable		 3ko0A-3i4qA:
21.99
3ko0C-3i4qA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_N_TFPN201_1
(PROTEIN S100-A4)		 3i4q APC40078
(Oleispira
antarctica) 		5 / 10 GLY A  57
GLY A  83
ILE A  29
PHE A  51
PHE A 138
 None
 1.19A 3ko0L-3i4qA:
undetectable
3ko0N-3i4qA:
undetectable		 3ko0L-3i4qA:
21.99
3ko0N-3i4qA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_R_TFPR201_1
(PROTEIN S100-A4)		 3i4q APC40078
(Oleispira
antarctica) 		5 / 10 GLY A  83
ILE A  29
PHE A  51
PHE A 138
GLY A  57
 None
 1.17A 3ko0R-3i4qA:
undetectable
3ko0T-3i4qA:
undetectable		 3ko0R-3i4qA:
21.99
3ko0T-3i4qA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2U_A_ELVA397_1
(INTEGRASE)		 3i4q APC40078
(Oleispira
antarctica) 		4 / 5 ASP A 103
ASP A  71
TYR A  58
GLU A 104
 NA  A 176 (-2.8A)
NA  A 176 (-3.0A)
None
None
 1.28A 3l2uA-3i4qA:
undetectable		 3l2uA-3i4qA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2V_A_RLTA397_1
(INTEGRASE)		 3i4q APC40078
(Oleispira
antarctica) 		4 / 7 ASP A 103
ASP A  71
TYR A  58
GLU A 104
 NA  A 176 (-2.8A)
NA  A 176 (-3.0A)
None
None
 1.25A 3l2vA-3i4qA:
undetectable		 3l2vA-3i4qA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2W_A_ELVA397_1
(INTEGRASE)		 3i4q APC40078
(Oleispira
antarctica) 		4 / 5 ASP A 103
ASP A  71
TYR A  58
GLU A 104
 NA  A 176 (-2.8A)
NA  A 176 (-3.0A)
None
None
 1.23A 3l2wA-3i4qA:
undetectable		 3l2wA-3i4qA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 3i4q APC40078
(Oleispira
antarctica) 		3 / 3 LYS A 143
ARG A  44
ASP A  66
 None
None
NA  A 176 (-2.9A)
 1.36A 3o7wA-3i4qA:
undetectable		 3o7wA-3i4qA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_B_ACTB403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 3i4q APC40078
(Oleispira
antarctica) 		3 / 3 ARG A  89
ASP A  15
ARG A  87
 None
 0.62A 4wq4B-3i4qA:
undetectable		 4wq4B-3i4qA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ5_B_ACTB404_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 3i4q APC40078
(Oleispira
antarctica) 		3 / 3 TYR A 142
ARG A  44
LYS A 143
 None
 1.30A 4wq5B-3i4qA:
undetectable		 4wq5B-3i4qA:
21.34