SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3i5q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3004_1
(SERUM ALBUMIN)		 3i5q NUCLEOPORIN NUP170
(Saccharomyces
cerevisiae) 		4 / 6 PHE B1416
PHE B1391
GLU B1447
LEU B1451
 None
 1.00A 1hk1A-3i5qB:
3.7		 1hk1A-3i5qB:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_B_ERYB1399_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 3i5q NUCLEOPORIN NUP170
(Saccharomyces
cerevisiae) 		5 / 12 ASN B1441
ILE B1412
TYR B1399
LEU B1451
SER B1409
 None
 1.29A 2iyfB-3i5qB:
undetectable		 2iyfB-3i5qB:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		 3i5q NUCLEOPORIN NUP170
(Saccharomyces
cerevisiae) 		4 / 6 GLU B1447
MET B1426
PHE B1416
ILE B1417
 None
 1.14A 2w98B-3i5qB:
undetectable		 2w98B-3i5qB:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M83_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 3i5q NUCLEOPORIN NUP170
(Saccharomyces
cerevisiae) 		5 / 11 ASN B1441
ILE B1412
TYR B1399
LEU B1451
SER B1409
 None
 1.28A 4m83A-3i5qB:
undetectable		 4m83A-3i5qB:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EVY_X_SALX502_1
(SALICYLATE
HYDROXYLASE)		 3i5q NUCLEOPORIN NUP170
(Saccharomyces
cerevisiae) 		4 / 5 SER B1437
MET B1448
LEU B1430
PHE B1444
 None
 1.28A 5evyX-3i5qB:
undetectable		 5evyX-3i5qB:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_H_FK5H201_1
(FK506-BINDING
PROTEIN 1)		 3i5q NUCLEOPORIN NUP170
(Saccharomyces
cerevisiae) 		4 / 8 PHE B1308
VAL B1335
ILE B1336
ILE B1374
 None
 0.79A 5hw8H-3i5qB:
undetectable		 5hw8H-3i5qB:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_A_Z80A401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3i5q NUCLEOPORIN NUP170
(Saccharomyces
cerevisiae) 		5 / 11 ILE B1271
ILE B1275
PHE B1311
VAL B1268
ASP B1298
 None
 1.15A 5lg3A-3i5qB:
undetectable		 5lg3A-3i5qB:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_F_Z80F401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3i5q NUCLEOPORIN NUP170
(Saccharomyces
cerevisiae) 		5 / 10 ILE B1271
ILE B1275
PHE B1311
VAL B1268
ASP B1298
 None
 1.12A 5lg3F-3i5qB:
undetectable		 5lg3F-3i5qB:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_G_Z80G401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3i5q NUCLEOPORIN NUP170
(Saccharomyces
cerevisiae) 		5 / 10 ILE B1271
ILE B1275
PHE B1311
VAL B1268
ASP B1298
 None
 1.10A 5lg3G-3i5qB:
undetectable		 5lg3G-3i5qB:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_H_Z80H401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3i5q NUCLEOPORIN NUP170
(Saccharomyces
cerevisiae) 		5 / 10 ILE B1271
ILE B1275
PHE B1311
VAL B1268
ASP B1298
 None
 1.13A 5lg3H-3i5qB:
undetectable		 5lg3H-3i5qB:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_J_Z80J401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3i5q NUCLEOPORIN NUP170
(Saccharomyces
cerevisiae) 		5 / 12 ILE B1271
ILE B1275
PHE B1311
VAL B1268
ASP B1298
 None
 1.15A 5lg3J-3i5qB:
undetectable		 5lg3J-3i5qB:
22.29