SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3i70'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DTL_A_BEPA206_1 (CARDIAC TROPONIN C)	3i70	AGRIN (Gallus gallus)	4 / 8	MET A 110 GLU A 119 GLU A 11 ARG A 5	None	1.23A	1dtlA-3i70A: undetectable	1dtlA-3i70A: 21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VJ1_A_BEZA1303_0 (SARS CORONAVIRUS MAIN PROTEINASE)	3i70	AGRIN (Gallus gallus)	3 / 3	HIS A 99 MET A 104 MET A 95	None	1.21A	2vj1A-3i70A: undetectable	2vj1A-3i70A: 18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FXF_A_BEZA601_0 (EUGENOL OXIDASE)	3i70	AGRIN (Gallus gallus)	5 / 9	TYR A 44 VAL A 88 ILE A 65 VAL A 63 LEU A 57	None	1.20A	5fxfA-3i70A: undetectable	5fxfA-3i70A: 14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FXF_B_BEZB601_0 (EUGENOL OXIDASE)	3i70	AGRIN (Gallus gallus)	5 / 10	TYR A 44 VAL A 88 ILE A 65 VAL A 63 LEU A 57	None	1.24A	5fxfB-3i70A: undetectable	5fxfB-3i70A: 14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M45_A_ACTA802_0 (ACETONE CARBOXYLASE ALPHA SUBUNIT)	3i70	AGRIN (Gallus gallus)	4 / 6	HIS A 99 ASP A 29 HIS A 32 MET A 95	None	1.22A	5m45A-3i70A: undetectable	5m45A-3i70A: 11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M45_D_ACTD802_0 (ACETONE CARBOXYLASE ALPHA SUBUNIT)	3i70	AGRIN (Gallus gallus)	4 / 6	HIS A 99 ASP A 29 HIS A 32 MET A 95	None	1.22A	5m45D-3i70A: undetectable	5m45D-3i70A: 11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M45_G_ACTG802_0 (ACETONE CARBOXYLASE ALPHA SUBUNIT)	3i70	AGRIN (Gallus gallus)	4 / 6	HIS A 99 ASP A 29 HIS A 32 MET A 95	None	1.21A	5m45G-3i70A: undetectable	5m45G-3i70A: 11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M45_J_ACTJ802_0 (ACETONE CARBOXYLASE ALPHA SUBUNIT)	3i70	AGRIN (Gallus gallus)	4 / 6	HIS A 99 ASP A 29 HIS A 32 MET A 95	None	1.22A	5m45J-3i70A: undetectable	5m45J-3i70A: 11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X7Z_A_BHAA201_0 (UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR RV2887)	3i70	AGRIN (Gallus gallus)	4 / 6	LEU A 103 VAL A 63 LEU A 57 VAL A 41	None	0.98A	5x7zA-3i70A: undetectable	5x7zA-3i70A: 17.86

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DTL_A_BEPA206_1","CARDIAC TROPONIN C","3i70","AGRIN","Gallus gallus",4,"MET A 110;GLU A 119;GLU A  11;ARG A   5","None","1.23A","1dtlA-3i70A:undetectable","1dtlA-3i70A:21.21"],["2VJ1_A_BEZA1303_0","SARS CORONAVIRUS MAIN PROTEINASE","3i70","AGRIN","Gallus gallus",3,"HIS A  99;MET A 104;MET A  95","None","1.21A","2vj1A-3i70A:undetectable","2vj1A-3i70A:18.75"],["5FXF_A_BEZA601_0","EUGENOL OXIDASE","3i70","AGRIN","Gallus gallus",5,"TYR A  44;VAL A  88;ILE A  65;VAL A  63;LEU A  57","None","1.20A","5fxfA-3i70A:undetectable","5fxfA-3i70A:14.86"],["5FXF_B_BEZB601_0","EUGENOL OXIDASE","3i70","AGRIN","Gallus gallus",5,"TYR A  44;VAL A  88;ILE A  65;VAL A  63;LEU A  57","None","1.24A","5fxfB-3i70A:undetectable","5fxfB-3i70A:14.86"],["5M45_A_ACTA802_0","ACETONE CARBOXYLASE ALPHA SUBUNIT","3i70","AGRIN","Gallus gallus",4,"HIS A  99;ASP A  29;HIS A  32;MET A  95","None","1.22A","5m45A-3i70A:undetectable","5m45A-3i70A:11.24"],["5M45_D_ACTD802_0","ACETONE CARBOXYLASE ALPHA SUBUNIT","3i70","AGRIN","Gallus gallus",4,"HIS A  99;ASP A  29;HIS A  32;MET A  95","None","1.22A","5m45D-3i70A:undetectable","5m45D-3i70A:11.24"],["5M45_G_ACTG802_0","ACETONE CARBOXYLASE ALPHA SUBUNIT","3i70","AGRIN","Gallus gallus",4,"HIS A  99;ASP A  29;HIS A  32;MET A  95","None","1.21A","5m45G-3i70A:undetectable","5m45G-3i70A:11.24"],["5M45_J_ACTJ802_0","ACETONE CARBOXYLASE ALPHA SUBUNIT","3i70","AGRIN","Gallus gallus",4,"HIS A  99;ASP A  29;HIS A  32;MET A  95","None","1.22A","5m45J-3i70A:undetectable","5m45J-3i70A:11.24"],["5X7Z_A_BHAA201_0","UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR RV2887","3i70","AGRIN","Gallus gallus",4,"LEU A 103;VAL A  63;LEU A  57;VAL A  41","None","0.98A","5x7zA-3i70A:undetectable","5x7zA-3i70A:17.86"]]