SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3i75'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 3i75 ANTIBODY LIGHT CHAIN
(Mus
musculus) 		4 / 4 THR B 128
PRO B 130
THR B 129
PRO B 158
 SO4  B 228 (-3.7A)
None
None
None
 1.35A 1dsdC-3i75B:
undetectable		 1dsdC-3i75B:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 3i75 ANTIBODY LIGHT CHAIN
(Mus
musculus) 		4 / 4 THR B 129
PRO B 158
THR B 128
PRO B 130
 None
None
SO4  B 228 (-3.7A)
None
 1.29A 1dsdC-3i75B:
undetectable		 1dsdC-3i75B:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 3i75 ANTIBODY LIGHT CHAIN
(Mus
musculus) 		4 / 4 THR B 128
PRO B 130
THR B 129
PRO B 158
 SO4  B 228 (-3.7A)
None
None
None
 1.35A 1dsdC-3i75B:
undetectable		 1dsdC-3i75B:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 3i75 ANTIBODY LIGHT CHAIN
(Mus
musculus) 		4 / 4 THR B 129
PRO B 158
THR B 128
PRO B 130
 None
None
SO4  B 228 (-3.7A)
None
 1.29A 1dsdC-3i75B:
undetectable		 1dsdC-3i75B:
9.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 3i75 ANTIBODY LIGHT CHAIN
(Mus
musculus) 		4 / 5 VAL B   2
TYR B  27
ARG B  98
TYR B 114
 None
 0.44A 4m7kH-3i75B:
27.3		 4m7kH-3i75B:
64.91