SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3i7d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3i7d SUGAR PHOSPHATE
ISOMERASE
(Ruegeria
pomeroyi) 		4 / 5 TYR A 128
MET A 133
THR A 145
LEU A 152
 CAC  A 164 (-4.3A)
None
None
None
 1.37A 2eimJ-3i7dA:
undetectable		 2eimJ-3i7dA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3i7d SUGAR PHOSPHATE
ISOMERASE
(Ruegeria
pomeroyi) 		4 / 5 TYR A 128
MET A 133
THR A 145
LEU A 152
 CAC  A 164 (-4.3A)
None
None
None
 1.39A 2eimW-3i7dA:
undetectable		 2eimW-3i7dA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 3i7d SUGAR PHOSPHATE
ISOMERASE
(Ruegeria
pomeroyi) 		4 / 5 TYR A 128
MET A 133
THR A 145
LEU A 152
 CAC  A 164 (-4.3A)
None
None
None
 1.34A 3ag1J-3i7dA:
undetectable		 3ag1J-3i7dA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 3i7d SUGAR PHOSPHATE
ISOMERASE
(Ruegeria
pomeroyi) 		4 / 5 TYR A 128
MET A 133
THR A 145
LEU A 152
 CAC  A 164 (-4.3A)
None
None
None
 1.41A 3ag2J-3i7dA:
undetectable		 3ag2J-3i7dA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 3i7d SUGAR PHOSPHATE
ISOMERASE
(Ruegeria
pomeroyi) 		4 / 5 TYR A 128
MET A 133
THR A 145
LEU A 152
 CAC  A 164 (-4.3A)
None
None
None
 1.40A 3ag4J-3i7dA:
undetectable		 3ag4J-3i7dA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3i7d SUGAR PHOSPHATE
ISOMERASE
(Ruegeria
pomeroyi) 		3 / 3 GLY A 158
PRO A  18
LEU A 152
 None
 0.57A 3hcpB-3i7dA:
undetectable		 3hcpB-3i7dA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAH_A_LNRA600_1
(PHENYLALANINE
HYDROXYLASE)		 3i7d SUGAR PHOSPHATE
ISOMERASE
(Ruegeria
pomeroyi) 		4 / 6 LEU A  49
HIS A  59
HIS A 102
GLU A  66
 None
CAC  A 164 (-3.5A)
ACT  A 165 (-3.7A)
ACT  A 165 (-3.8A)
 1.09A 4pahA-3i7dA:
undetectable		 4pahA-3i7dA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3i7d SUGAR PHOSPHATE
ISOMERASE
(Ruegeria
pomeroyi) 		4 / 5 TYR A 128
MET A 133
THR A 145
LEU A 152
 CAC  A 164 (-4.3A)
None
None
None
 1.38A 5w97J-3i7dA:
undetectable		 5w97J-3i7dA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3i7d SUGAR PHOSPHATE
ISOMERASE
(Ruegeria
pomeroyi) 		4 / 5 TYR A 128
MET A 133
THR A 145
LEU A 152
 CAC  A 164 (-4.3A)
None
None
None
 1.36A 5wauJ-3i7dA:
undetectable		 5wauJ-3i7dA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3i7d SUGAR PHOSPHATE
ISOMERASE
(Ruegeria
pomeroyi) 		4 / 5 TYR A 128
MET A 133
THR A 145
LEU A 152
 CAC  A 164 (-4.3A)
None
None
None
 1.37A 5x19J-3i7dA:
undetectable		 5x19J-3i7dA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3i7d SUGAR PHOSPHATE
ISOMERASE
(Ruegeria
pomeroyi) 		4 / 5 TYR A 128
MET A 133
THR A 145
LEU A 152
 CAC  A 164 (-4.3A)
None
None
None
 1.40A 5x1bJ-3i7dA:
undetectable		 5x1bJ-3i7dA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3i7d SUGAR PHOSPHATE
ISOMERASE
(Ruegeria
pomeroyi) 		4 / 5 TYR A 128
MET A 133
THR A 145
LEU A 152
 CAC  A 164 (-4.3A)
None
None
None
 1.34A 5x1bW-3i7dA:
undetectable		 5x1bW-3i7dA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3i7d SUGAR PHOSPHATE
ISOMERASE
(Ruegeria
pomeroyi) 		4 / 5 TYR A 128
MET A 133
THR A 145
LEU A 152
 CAC  A 164 (-4.3A)
None
None
None
 1.40A 5z86J-3i7dA:
undetectable		 5z86J-3i7dA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA607_0
(TYROSINASE)		 3i7d SUGAR PHOSPHATE
ISOMERASE
(Ruegeria
pomeroyi) 		3 / 3 HIS A  59
HIS A 102
HIS A  61
 CAC  A 164 (-3.5A)
ACT  A 165 (-3.7A)
CAC  A 164 (-4.4A)
 0.55A 5zrdA-3i7dA:
undetectable		 5zrdA-3i7dA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3i7d SUGAR PHOSPHATE
ISOMERASE
(Ruegeria
pomeroyi) 		4 / 5 TYR A 128
MET A 133
THR A 145
LEU A 152
 CAC  A 164 (-4.3A)
None
None
None
 1.39A 6nknJ-3i7dA:
undetectable		 6nknJ-3i7dA:
16.78