SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3i7m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OT7_B_IU5B1002_1
(BILE ACID RECEPTOR)		 3i7m XAA-PRO DIPEPTIDASE
(Lactobacillus
brevis) 		5 / 12 LEU A 115
PHE A  53
ILE A  86
TYR A  76
TRP A  83
 None
 1.32A 1ot7B-3i7mA:
undetectable		 1ot7B-3i7mA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3i7m XAA-PRO DIPEPTIDASE
(Lactobacillus
brevis) 		4 / 4 ALA A 101
VAL A 100
ALA A  16
HIS A  14
 None
 1.18A 1q23K-3i7mA:
undetectable		 1q23K-3i7mA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA503_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 3i7m XAA-PRO DIPEPTIDASE
(Lactobacillus
brevis) 		4 / 6 LYS A   2
ILE A   7
VAL A  46
LEU A  44
 None
 1.12A 4em2A-3i7mA:
undetectable		 4em2A-3i7mA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3i7m XAA-PRO DIPEPTIDASE
(Lactobacillus
brevis) 		4 / 7 THR A  26
LEU A  30
LEU A  44
THR A  19
 None
 0.79A 4z90A-3i7mA:
undetectable
4z90B-3i7mA:
undetectable
4z90C-3i7mA:
undetectable
4z90D-3i7mA:
undetectable
4z90E-3i7mA:
undetectable		 4z90A-3i7mA:
18.15
4z90B-3i7mA:
18.15
4z90C-3i7mA:
18.15
4z90D-3i7mA:
18.15
4z90E-3i7mA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3i7m XAA-PRO DIPEPTIDASE
(Lactobacillus
brevis) 		4 / 4 GLN A   6
THR A   2
LEU A  44
LEU A  30
 None
 1.20A 5m5kB-3i7mA:
undetectable		 5m5kB-3i7mA:
13.08