SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3i86'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P7L_C_SAMC685_0 (S-ADENOSYLMETHIONINE SYNTHETASE)	3i86	PUTATIVE UNCHARACTERIZED PROTEIN (Mycobacterium avium)	4 / 8	PRO A 171 THR A 235 PHE A 196 ASP A 176	None	1.12A	1p7lC-3i86A: undetectable	1p7lC-3i86A: 18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P7L_C_SAMC885_1 (S-ADENOSYLMETHIONINE SYNTHETASE)	3i86	PUTATIVE UNCHARACTERIZED PROTEIN (Mycobacterium avium)	4 / 8	PRO A 171 THR A 235 PHE A 196 ASP A 176	None	1.11A	1p7lD-3i86A: undetectable	1p7lD-3i86A: 18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RG9_A_SAMA385_0 (S-ADENOSYLMETHIONINE SYNTHETASE)	3i86	PUTATIVE UNCHARACTERIZED PROTEIN (Mycobacterium avium)	4 / 8	PRO A 171 THR A 235 PHE A 196 ASP A 176	None	1.11A	1rg9A-3i86A: undetectable	1rg9A-3i86A: 18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RG9_B_SAMB485_1 (S-ADENOSYLMETHIONINE SYNTHETASE)	3i86	PUTATIVE UNCHARACTERIZED PROTEIN (Mycobacterium avium)	4 / 8	PRO A 171 THR A 235 PHE A 196 ASP A 176	None	1.08A	1rg9B-3i86A: undetectable	1rg9B-3i86A: 18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RG9_C_SAMC585_0 (S-ADENOSYLMETHIONINE SYNTHETASE)	3i86	PUTATIVE UNCHARACTERIZED PROTEIN (Mycobacterium avium)	4 / 8	PRO A 171 THR A 235 PHE A 196 ASP A 176	None	1.11A	1rg9C-3i86A: undetectable	1rg9C-3i86A: 18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RG9_C_SAMC685_1 (S-ADENOSYLMETHIONINE SYNTHETASE)	3i86	PUTATIVE UNCHARACTERIZED PROTEIN (Mycobacterium avium)	4 / 8	PRO A 171 THR A 235 PHE A 196 ASP A 176	None	1.10A	1rg9D-3i86A: undetectable	1rg9D-3i86A: 18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WA2_A_SAMA1248_0 (NON-STRUCTURAL PROTEIN 5)	3i86	PUTATIVE UNCHARACTERIZED PROTEIN (Mycobacterium avium)	5 / 12	GLY A 145 GLY A 152 GLY A 134 LEU A 158 VAL A 128	None	1.17A	2wa2A-3i86A: undetectable	2wa2A-3i86A: 18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_D_DHID32_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	3i86	PUTATIVE UNCHARACTERIZED PROTEIN (Mycobacterium avium)	5 / 6	GLY A 134 GLY A 143 GLY A 147 GLY A 133 GLY A 145	None	0.82A	3bogB-3i86A: 0.0 3bogD-3i86A: 0.0	3bogB-3i86A: undetectable 3bogD-3i86A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5T8S_B_SAMB402_1 (S-ADENOSYLMETHIONINE SYNTHASE)	3i86	PUTATIVE UNCHARACTERIZED PROTEIN (Mycobacterium avium)	4 / 8	PRO A 171 THR A 235 PHE A 196 ASP A 176	None	1.21A	5t8sB-3i86A: undetectable	5t8sB-3i86A: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AG0_A_ACRA606_0 (ALPHA-AMYLASE)	3i86	PUTATIVE UNCHARACTERIZED PROTEIN (Mycobacterium avium)	5 / 7	GLY A 233 GLY A 198 PRO A 199 GLY A 200 GLY A 201	None	0.98A	6ag0A-3i86A: undetectable	6ag0A-3i86A: 17.27

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1P7L_C_SAMC685_0","S-ADENOSYLMETHIONINE SYNTHETASE","3i86","PUTATIVE UNCHARACTERIZED PROTEIN","Mycobacterium avium",4,"PRO A 171;THR A 235;PHE A 196;ASP A 176","None","1.12A","1p7lC-3i86A:undetectable","1p7lC-3i86A:18.89"],["1P7L_C_SAMC885_1","S-ADENOSYLMETHIONINE SYNTHETASE","3i86","PUTATIVE UNCHARACTERIZED PROTEIN","Mycobacterium avium",4,"PRO A 171;THR A 235;PHE A 196;ASP A 176","None","1.11A","1p7lD-3i86A:undetectable","1p7lD-3i86A:18.89"],["1RG9_A_SAMA385_0","S-ADENOSYLMETHIONINE SYNTHETASE","3i86","PUTATIVE UNCHARACTERIZED PROTEIN","Mycobacterium avium",4,"PRO A 171;THR A 235;PHE A 196;ASP A 176","None","1.11A","1rg9A-3i86A:undetectable","1rg9A-3i86A:18.89"],["1RG9_B_SAMB485_1","S-ADENOSYLMETHIONINE SYNTHETASE","3i86","PUTATIVE UNCHARACTERIZED PROTEIN","Mycobacterium avium",4,"PRO A 171;THR A 235;PHE A 196;ASP A 176","None","1.08A","1rg9B-3i86A:undetectable","1rg9B-3i86A:18.89"],["1RG9_C_SAMC585_0","S-ADENOSYLMETHIONINE SYNTHETASE","3i86","PUTATIVE UNCHARACTERIZED PROTEIN","Mycobacterium avium",4,"PRO A 171;THR A 235;PHE A 196;ASP A 176","None","1.11A","1rg9C-3i86A:undetectable","1rg9C-3i86A:18.89"],["1RG9_C_SAMC685_1","S-ADENOSYLMETHIONINE SYNTHETASE","3i86","PUTATIVE UNCHARACTERIZED PROTEIN","Mycobacterium avium",4,"PRO A 171;THR A 235;PHE A 196;ASP A 176","None","1.10A","1rg9D-3i86A:undetectable","1rg9D-3i86A:18.89"],["2WA2_A_SAMA1248_0","NON-STRUCTURAL PROTEIN 5","3i86","PUTATIVE UNCHARACTERIZED PROTEIN","Mycobacterium avium",5,"GLY A 145;GLY A 152;GLY A 134;LEU A 158;VAL A 128","None","1.17A","2wa2A-3i86A:undetectable","2wa2A-3i86A:18.84"],["3BOG_D_DHID32_0","6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN","3i86","PUTATIVE UNCHARACTERIZED PROTEIN","Mycobacterium avium",5,"GLY A 134;GLY A 143;GLY A 147;GLY A 133;GLY A 145","None","0.82A","3bogB-3i86A:0.0;3bogD-3i86A:0.0","3bogB-3i86A:undetectable;3bogD-3i86A:undetectable"],["5T8S_B_SAMB402_1","S-ADENOSYLMETHIONINE SYNTHASE","3i86","PUTATIVE UNCHARACTERIZED PROTEIN","Mycobacterium avium",4,"PRO A 171;THR A 235;PHE A 196;ASP A 176","None","1.21A","5t8sB-3i86A:undetectable","5t8sB-3i86A:16.67"],["6AG0_A_ACRA606_0","ALPHA-AMYLASE","3i86","PUTATIVE UNCHARACTERIZED PROTEIN","Mycobacterium avium",5,"GLY A 233;GLY A 198;PRO A 199;GLY A 200;GLY A 201","None","0.98A","6ag0A-3i86A:undetectable","6ag0A-3i86A:17.27"]]