SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3i91'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETA_1_T441128_1
(TRANSTHYRETIN)		 3i91 CHROMOBOX PROTEIN
HOMOLOG 8
(Homo
sapiens) 		4 / 5 LEU A  53
GLU A  14
ALA A  56
LEU A  54
 None
 1.05A 1eta1-3i91A:
undetectable		 1eta1-3i91A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETA_2_T442129_1
(TRANSTHYRETIN)		 3i91 CHROMOBOX PROTEIN
HOMOLOG 8
(Homo
sapiens) 		4 / 5 LEU A  53
GLU A  14
ALA A  56
LEU A  54
 None
 1.04A 1eta2-3i91A:
undetectable		 1eta2-3i91A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_1_T441128_1
(TRANSTHYRETIN)		 3i91 CHROMOBOX PROTEIN
HOMOLOG 8
(Homo
sapiens) 		4 / 6 LEU A  53
GLU A  14
ALA A  56
LEU A  54
 None
 1.07A 1etb1-3i91A:
undetectable		 1etb1-3i91A:
18.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X3U_B_SVRB101_1
(CHROMOBOX PROTEIN
HOMOLOG 7)		 3i91 CHROMOBOX PROTEIN
HOMOLOG 8
(Homo
sapiens) 		8 / 9 ARG A  20
LEU A  29
TRP A  32
TRP A  35
TYR A  39
THR A  41
TRP A  42
LEU A  49
 None
 0.75A 4x3uA-3i91A:
8.5		 4x3uA-3i91A:
68.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X3U_B_SVRB101_2
(CHROMOBOX PROTEIN
HOMOLOG 7)		 3i91 CHROMOBOX PROTEIN
HOMOLOG 8
(Homo
sapiens) 		6 / 10 ARG A  20
ARG A  22
LEU A  29
THR A  41
TRP A  42
LEU A  49
 None
 0.69A 4x3uB-3i91A:
9.7		 4x3uB-3i91A:
68.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X3U_B_SVRB101_2
(CHROMOBOX PROTEIN
HOMOLOG 7)		 3i91 CHROMOBOX PROTEIN
HOMOLOG 8
(Homo
sapiens) 		7 / 10 ARG A  20
ARG A  22
LEU A  29
TRP A  32
TRP A  35
THR A  41
TRP A  42
 None
 0.75A 4x3uB-3i91A:
9.7		 4x3uB-3i91A:
68.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X3U_B_SVRB101_2
(CHROMOBOX PROTEIN
HOMOLOG 7)		 3i91 CHROMOBOX PROTEIN
HOMOLOG 8
(Homo
sapiens) 		7 / 10 ARG A  20
LEU A  29
TRP A  32
TRP A  35
TYR A  39
THR A  41
TRP A  42
 None
 0.75A 4x3uB-3i91A:
9.7		 4x3uB-3i91A:
68.52