SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3i93'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S8P_B_SAMB500_1 (HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1)	3i93	DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE (Mycobacterium tuberculosis)	3 / 3	HIS A 62 SER A 74 ASN A 77	None TRS A 202 (-3.0A) DUP A 201 (-3.2A)	0.82A	3s8pB-3i93A: undetectable	3s8pB-3i93A: 20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CPR_B_SAMB402_1 (HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1)	3i93	DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE (Mycobacterium tuberculosis)	3 / 3	HIS A 62 SER A 74 ASN A 77	None TRS A 202 (-3.0A) DUP A 201 (-3.2A)	0.89A	5cprB-3i93A: undetectable	5cprB-3i93A: 21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5I71_A_68PA701_1 (SODIUM-DEPENDENT SEROTONIN TRANSPORTER)	3i93	DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE (Mycobacterium tuberculosis)	5 / 12	ILE A 90 ALA A 50 GLY A 48 GLY A 80 VAL A 61	DUP A 201 (-4.7A) None None DUP A 201 (-3.4A) DUP A 201 ( 4.8A)	1.30A	5i71A-3i93A: undetectable	5i71A-3i93A: 14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5I75_A_68PA701_1 (SODIUM-DEPENDENT SEROTONIN TRANSPORTER)	3i93	DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE (Mycobacterium tuberculosis)	5 / 12	ILE A 90 ALA A 50 GLY A 48 GLY A 80 VAL A 61	DUP A 201 (-4.7A) None None DUP A 201 (-3.4A) DUP A 201 ( 4.8A)	1.24A	5i75A-3i93A: undetectable	5i75A-3i93A: 14.90

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3S8P_B_SAMB500_1","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","3i93","DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE","Mycobacterium tuberculosis",3,"HIS A  62;SER A  74;ASN A  77","None;TRS A 202 (-3.0A);DUP A 201 (-3.2A)","0.82A","3s8pB-3i93A:undetectable","3s8pB-3i93A:20.94"],["5CPR_B_SAMB402_1","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","3i93","DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE","Mycobacterium tuberculosis",3,"HIS A  62;SER A  74;ASN A  77","None;TRS A 202 (-3.0A);DUP A 201 (-3.2A)","0.89A","5cprB-3i93A:undetectable","5cprB-3i93A:21.45"],["5I71_A_68PA701_1","SODIUM-DEPENDENT SEROTONIN TRANSPORTER","3i93","DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE","Mycobacterium tuberculosis",5,"ILE A  90;ALA A  50;GLY A  48;GLY A  80;VAL A  61","DUP A 201 (-4.7A);None;None;DUP A 201 (-3.4A);DUP A 201 ( 4.8A)","1.30A","5i71A-3i93A:undetectable","5i71A-3i93A:14.90"],["5I75_A_68PA701_1","SODIUM-DEPENDENT SEROTONIN TRANSPORTER","3i93","DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE","Mycobacterium tuberculosis",5,"ILE A  90;ALA A  50;GLY A  48;GLY A  80;VAL A  61","DUP A 201 (-4.7A);None;None;DUP A 201 (-3.4A);DUP A 201 ( 4.8A)","1.24A","5i75A-3i93A:undetectable","5i75A-3i93A:14.90"]]