SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3i9k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ISM_A_NCAA303_0
(BONE MARROW STROMAL
CELL ANTIGEN 1)		 3i9k ADP-RIBOSYL CYCLASE
(Aplysia
californica) 		5 / 9 TRP A  77
LEU A  97
TRP A 140
SER A 144
PHE A 174
 None
 0.40A 1ismA-3i9kA:
28.4		 1ismA-3i9kA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ISM_B_NCAB305_0
(BONE MARROW STROMAL
CELL ANTIGEN 1)		 3i9k ADP-RIBOSYL CYCLASE
(Aplysia
californica) 		4 / 7 TRP A  77
LEU A  97
TRP A 140
PHE A 174
 None
 0.31A 1ismB-3i9kA:
28.5		 1ismB-3i9kA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1R15_A_NCAA319_0
(ADP-RIBOSYL CYCLASE)		 3i9k ADP-RIBOSYL CYCLASE
(Aplysia
californica) 		4 / 4 TRP A  77
GLU A  98
ASN A 107
TRP A 140
 None
 0.34A 1r15A-3i9kA:
39.6		 1r15A-3i9kA:
99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1R15_A_NCAA419_0
(ADP-RIBOSYL CYCLASE)		 3i9k ADP-RIBOSYL CYCLASE
(Aplysia
californica) 		4 / 4 VAL A 110
TRP A 111
PHE A 139
TRP A 140
 None
 0.14A 1r15A-3i9kA:
39.6		 1r15A-3i9kA:
99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1R15_B_NCAB329_0
(ADP-RIBOSYL CYCLASE)		 3i9k ADP-RIBOSYL CYCLASE
(Aplysia
californica) 		4 / 4 TRP A  77
GLU A  98
ASN A 107
TRP A 140
 None
 0.41A 1r15B-3i9kA:
39.4		 1r15B-3i9kA:
99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1R15_B_NCAB429_0
(ADP-RIBOSYL CYCLASE)		 3i9k ADP-RIBOSYL CYCLASE
(Aplysia
californica) 		4 / 4 VAL A 110
TRP A 111
PHE A 139
TRP A 140
 None
 0.14A 1r15B-3i9kA:
39.4		 1r15B-3i9kA:
99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 3i9k ADP-RIBOSYL CYCLASE
(Aplysia
californica) 		3 / 3 GLU A  98
ASN A 107
TRP A 140
 None
 0.33A 1r15C-3i9kA:
39.6		 1r15C-3i9kA:
99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1R15_C_NCAC439_0
(ADP-RIBOSYL CYCLASE)		 3i9k ADP-RIBOSYL CYCLASE
(Aplysia
californica) 		3 / 3 TRP A 111
PHE A 139
TRP A 140
 None
 0.14A 1r15C-3i9kA:
39.6		 1r15C-3i9kA:
99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1R15_D_NCAD349_0
(ADP-RIBOSYL CYCLASE)		 3i9k ADP-RIBOSYL CYCLASE
(Aplysia
californica) 		3 / 3 GLU A  98
ASN A 107
TRP A 140
 None
 0.27A 1r15D-3i9kA:
39.5		 1r15D-3i9kA:
99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1R15_D_NCAD449_0
(ADP-RIBOSYL CYCLASE)		 3i9k ADP-RIBOSYL CYCLASE
(Aplysia
californica) 		4 / 4 VAL A 110
TRP A 111
PHE A 139
TRP A 140
 None
 0.15A 1r15D-3i9kA:
39.5		 1r15D-3i9kA:
99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 3i9k ADP-RIBOSYL CYCLASE
(Aplysia
californica) 		3 / 3 GLU A  98
ASN A 107
TRP A 140
 None
 0.30A 1r15E-3i9kA:
39.6		 1r15E-3i9kA:
99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1R15_E_NCAE459_0
(ADP-RIBOSYL CYCLASE)		 3i9k ADP-RIBOSYL CYCLASE
(Aplysia
californica) 		4 / 4 VAL A 110
TRP A 111
PHE A 139
TRP A 140
 None
 0.14A 1r15E-3i9kA:
39.6		 1r15E-3i9kA:
99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 3i9k ADP-RIBOSYL CYCLASE
(Aplysia
californica) 		3 / 3 GLU A  98
ASN A 107
TRP A 140
 None
 0.20A 1r15F-3i9kA:
39.4		 1r15F-3i9kA:
99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1R15_F_NCAF469_0
(ADP-RIBOSYL CYCLASE)		 3i9k ADP-RIBOSYL CYCLASE
(Aplysia
californica) 		3 / 3 TRP A 111
PHE A 139
TRP A 140
 None
 0.14A 1r15F-3i9kA:
39.4		 1r15F-3i9kA:
99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1R15_G_NCAG379_0
(ADP-RIBOSYL CYCLASE)		 3i9k ADP-RIBOSYL CYCLASE
(Aplysia
californica) 		4 / 4 TRP A  77
GLU A  98
ASN A 107
TRP A 140
 None
 0.41A 1r15G-3i9kA:
39.3		 1r15G-3i9kA:
99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1R15_G_NCAG479_0
(ADP-RIBOSYL CYCLASE)		 3i9k ADP-RIBOSYL CYCLASE
(Aplysia
californica) 		3 / 3 TRP A 111
PHE A 139
TRP A 140
 None
 0.15A 1r15G-3i9kA:
39.3		 1r15G-3i9kA:
99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1R15_H_NCAH389_0
(ADP-RIBOSYL CYCLASE)		 3i9k ADP-RIBOSYL CYCLASE
(Aplysia
californica) 		4 / 4 TRP A  77
GLU A  98
ASN A 107
TRP A 140
 None
 0.41A 1r15H-3i9kA:
39.5		 1r15H-3i9kA:
99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1R15_H_NCAH489_0
(ADP-RIBOSYL CYCLASE)		 3i9k ADP-RIBOSYL CYCLASE
(Aplysia
californica) 		3 / 3 TRP A 111
PHE A 139
TRP A 140
 None
 0.15A 1r15H-3i9kA:
39.5		 1r15H-3i9kA:
99.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_ACTH611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3i9k ADP-RIBOSYL CYCLASE
(Aplysia
californica) 		4 / 6 LEU A 106
LEU A   7
TRP A 111
PHE A  45
 None
 1.14A 1ru9H-3i9kA:
undetectable
1ru9L-3i9kA:
undetectable		 1ru9H-3i9kA:
19.08
1ru9L-3i9kA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_L_ACTL611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3i9k ADP-RIBOSYL CYCLASE
(Aplysia
californica) 		4 / 6 LEU A 106
LEU A   7
TRP A 111
PHE A  45
 None
 1.16A 1rukH-3i9kA:
undetectable
1rukL-3i9kA:
undetectable		 1rukH-3i9kA:
19.08
1rukL-3i9kA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X9G_A_LYAA1270_2
(PTERIDINE REDUCTASE)		 3i9k ADP-RIBOSYL CYCLASE
(Aplysia
californica) 		3 / 3 MET A 158
VAL A 218
GLU A 154
 None
 0.90A 2x9gA-3i9kA:
3.3		 2x9gA-3i9kA:
19.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZG_A_NCAA302_0
(ADP-RIBOSYL CYCLASE
1)		 3i9k ADP-RIBOSYL CYCLASE
(Aplysia
californica) 		5 / 7 TRP A  77
LEU A  97
GLU A  98
TRP A 140
SER A 144
 None
 0.45A 3dzgA-3i9kA:
25.3		 3dzgA-3i9kA:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZG_B_NCAB302_0
(ADP-RIBOSYL CYCLASE
1)		 3i9k ADP-RIBOSYL CYCLASE
(Aplysia
californica) 		5 / 7 TRP A  77
LEU A  97
GLU A  98
TRP A 140
SER A 144
 None
 0.40A 3dzgB-3i9kA:
25.1		 3dzgB-3i9kA:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3I9J_B_NCAB302_0
(ADP-RIBOSYL CYCLASE)		 3i9k ADP-RIBOSYL CYCLASE
(Aplysia
californica) 		6 / 6 LEU A  97
GLU A  98
ASN A 107
TRP A 140
SER A 144
PHE A 174
 None
 0.28A 3i9jB-3i9kA:
38.2		 3i9jB-3i9kA:
99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ROP_A_NCAA302_0
(ADP-RIBOSYL CYCLASE
1)		 3i9k ADP-RIBOSYL CYCLASE
(Aplysia
californica) 		5 / 6 TRP A  77
LEU A  97
GLU A  98
TRP A 140
SER A 144
 None
 0.36A 3ropA-3i9kA:
25.3		 3ropA-3i9kA:
32.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3i9k ADP-RIBOSYL CYCLASE
(Aplysia
californica) 		4 / 8 SER A 162
ARG A 246
ILE A 202
GLU A 200
 None
 1.11A 4cx7A-3i9kA:
undetectable
4cx7B-3i9kA:
undetectable		 4cx7A-3i9kA:
19.91
4cx7B-3i9kA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_C_H4BC600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3i9k ADP-RIBOSYL CYCLASE
(Aplysia
californica) 		4 / 8 SER A 162
ARG A 246
ILE A 202
GLU A 200
 None
 1.15A 4cx7C-3i9kA:
undetectable
4cx7D-3i9kA:
undetectable		 4cx7C-3i9kA:
19.91
4cx7D-3i9kA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_3
(HIV-1 PROTEASE)		 3i9k ADP-RIBOSYL CYCLASE
(Aplysia
californica) 		3 / 3 ASP A  82
LEU A 195
VAL A 166
 None
 0.60A 4jecB-3i9kA:
undetectable		 4jecB-3i9kA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_A_CVIA608_0
(ACETYLCHOLINESTERASE)		 3i9k ADP-RIBOSYL CYCLASE
(Aplysia
californica) 		4 / 7 TYR A  23
ASP A  99
THR A  90
THR A  96
 None
 1.11A 5ov9A-3i9kA:
undetectable		 5ov9A-3i9kA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PBE_A_TYLA2001_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 3i9k ADP-RIBOSYL CYCLASE
(Aplysia
californica) 		4 / 6 PRO A 167
VAL A 159
VAL A 192
TYR A 157
 None
 0.81A 5pbeA-3i9kA:
undetectable		 5pbeA-3i9kA:
17.69