SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3i9s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_A_SAMA301_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 3i9s INTEGRON CASSETTE
PROTEIN
(Vibrio
cholerae) 		5 / 12 ILE A  21
ALA A  68
ASP A  87
ALA A  57
LEU A  16
 None
 0.95A 2yqzA-3i9sA:
undetectable		 2yqzA-3i9sA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3i9s INTEGRON CASSETTE
PROTEIN
(Vibrio
cholerae) 		5 / 12 ILE A  56
VAL A  55
GLY A  66
ALA A  68
ILE A  21
 None
 1.03A 3mb5A-3i9sA:
undetectable		 3mb5A-3i9sA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_B_ADNB401_2
(PUTATIVE ADENOSINE
KINASE)		 3i9s INTEGRON CASSETTE
PROTEIN
(Vibrio
cholerae) 		4 / 4 LEU A 103
GLY A 100
MET A  85
PHE A  67
 None
 1.14A 3vaqB-3i9sA:
undetectable		 3vaqB-3i9sA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_2
(SEPIAPTERIN
REDUCTASE)		 3i9s INTEGRON CASSETTE
PROTEIN
(Vibrio
cholerae) 		3 / 3 LEU A 107
MET A  85
ASP A   9
 None
None
SO4  A 163 (-4.8A)
 0.78A 4j7xB-3i9sA:
undetectable		 4j7xB-3i9sA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KSZ_A_CYSA620_0
(LACTOPEROXIDASE)		 3i9s INTEGRON CASSETTE
PROTEIN
(Vibrio
cholerae) 		3 / 3 ARG A  25
GLU A  22
PHE A  89
 None
 0.95A 4kszA-3i9sA:
undetectable		 4kszA-3i9sA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_D_SAMD201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 3i9s INTEGRON CASSETTE
PROTEIN
(Vibrio
cholerae) 		6 / 11 LEU A  38
ASP A  37
LEU A  42
SER A  43
LEU A  14
VAL A  17
 None
 1.26A 5twjD-3i9sA:
undetectable		 5twjD-3i9sA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CK2_C_IPHC101_0
(INSULIN A CHAIN
INSULIN B CHAIN)		 3i9s INTEGRON CASSETTE
PROTEIN
(Vibrio
cholerae) 		4 / 4 ILE A  99
LEU A  88
HIS A 106
ALA A  68
 None
 1.04A 6ck2C-3i9sA:
undetectable
6ck2D-3i9sA:
undetectable		 6ck2C-3i9sA:
10.79
6ck2D-3i9sA:
15.18