SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3i9w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AQB_A_RTLA185_0
(RETINOL-BINDING
PROTEIN)		 3i9w SENSOR PROTEIN TORS
(Escherichia
coli) 		5 / 10 LEU A 144
VAL A 249
TYR A 189
LEU A 196
GLN A 148
 None
 1.38A 1aqbA-3i9wA:
undetectable		 1aqbA-3i9wA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HBP_A_RTLA184_0
(RETINOL BINDING
PROTEIN)		 3i9w SENSOR PROTEIN TORS
(Escherichia
coli) 		5 / 11 LEU A 144
VAL A 249
TYR A 189
LEU A 196
GLN A 148
 None
 1.31A 1hbpA-3i9wA:
undetectable		 1hbpA-3i9wA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3004_1
(SERUM ALBUMIN)		 3i9w SENSOR PROTEIN TORS
(Escherichia
coli) 		4 / 7 ALA A 229
LEU A 226
VAL A 207
MET A 206
 None
 0.94A 1hk2A-3i9wA:
undetectable		 1hk2A-3i9wA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 3i9w SENSOR PROTEIN TORS
(Escherichia
coli) 		5 / 11 LEU A 144
VAL A 249
TYR A 189
LEU A 196
GLN A 148
 None
 1.35A 1kt6A-3i9wA:
undetectable		 1kt6A-3i9wA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT7_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 3i9w SENSOR PROTEIN TORS
(Escherichia
coli) 		5 / 11 LEU A 144
VAL A 249
TYR A 189
LEU A 196
GLN A 148
 None
 1.31A 1kt7A-3i9wA:
undetectable		 1kt7A-3i9wA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA140_0
(LYSOZYME C)		 3i9w SENSOR PROTEIN TORS
(Escherichia
coli) 		3 / 3 ASN A  58
ALA A  62
ASN A  64
 None
 0.81A 1n4fA-3i9wA:
undetectable		 1n4fA-3i9wA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_B_DESB128_1
(TRANSTHYRETIN)		 3i9w SENSOR PROTEIN TORS
(Escherichia
coli) 		5 / 11 LEU A  59
LEU A 110
SER A 109
LEU A 276
LEU A 279
 None
 1.31A 1tz8A-3i9wA:
undetectable
1tz8B-3i9wA:
undetectable		 1tz8A-3i9wA:
18.06
1tz8B-3i9wA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_B_DESB128_1
(TRANSTHYRETIN)		 3i9w SENSOR PROTEIN TORS
(Escherichia
coli) 		5 / 11 LEU A 276
LEU A 279
LEU A  59
LEU A 110
SER A 109
 None
 1.31A 1tz8A-3i9wA:
undetectable
1tz8B-3i9wA:
undetectable		 1tz8A-3i9wA:
18.06
1tz8B-3i9wA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FJ1_A_CTCA222_0
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 3i9w SENSOR PROTEIN TORS
(Escherichia
coli) 		5 / 12 SER A 292
ARG A  43
VAL A 298
LEU A  85
SER A  49
 None
 1.42A 2fj1A-3i9wA:
4.5		 2fj1A-3i9wA:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_B_IMNB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3i9w SENSOR PROTEIN TORS
(Escherichia
coli) 		5 / 11 SER A  49
ALA A  48
ILE A  82
LEU A  86
LEU A  89
 None
 1.15A 4xumB-3i9wA:
undetectable		 4xumB-3i9wA:
25.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_2
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 3i9w SENSOR PROTEIN TORS
(Escherichia
coli) 		4 / 6 ARG A 111
LEU A 110
ALA A  55
GLN A 112
 None
 1.09A 6b89B-3i9wA:
undetectable		 6b89B-3i9wA:
17.41