SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3i9x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H9Z_A_RWFA3001_1
(SERUM ALBUMIN)		 3i9x MUTT/NUDIX FAMILY
PROTEIN
(Listeria
innocua) 		5 / 11 PHE A 145
ALA A 150
LEU A 163
LEU A  48
ALA A 156
 None
 1.12A 1h9zA-3i9xA:
undetectable		 1h9zA-3i9xA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDN_A_LEUA487_0
(L-AMINO ACID OXIDASE)		 3i9x MUTT/NUDIX FAMILY
PROTEIN
(Listeria
innocua) 		4 / 7 ARG A 113
HIS A 159
PHE A 157
ILE A  49
 None
GOL  A 186 (-4.1A)
GOL  A 186 ( 4.2A)
None
 1.12A 1tdnA-3i9xA:
undetectable		 1tdnA-3i9xA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3i9x MUTT/NUDIX FAMILY
PROTEIN
(Listeria
innocua) 		5 / 12 ILE A  49
GLY A 136
ALA A 135
GLY A 143
LEU A 144
 None
 0.96A 4e1gA-3i9xA:
undetectable		 4e1gA-3i9xA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_B_LNLB701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3i9x MUTT/NUDIX FAMILY
PROTEIN
(Listeria
innocua) 		5 / 12 ILE A  49
GLY A 136
ALA A 135
GLY A 143
LEU A 144
 None
 0.96A 4e1gB-3i9xA:
undetectable		 4e1gB-3i9xA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_A_SAMA1546_0
(CYSTATHIONINE
BETA-SYNTHASE)		 3i9x MUTT/NUDIX FAMILY
PROTEIN
(Listeria
innocua) 		5 / 11 ALA A 129
HIS A  45
VAL A 125
THR A  33
ILE A  31
 None
 1.29A 4uuuA-3i9xA:
undetectable
4uuuB-3i9xA:
undetectable		 4uuuA-3i9xA:
20.63
4uuuB-3i9xA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_C_08JC602_1
(CYTOCHROME P450 3A4)		 3i9x MUTT/NUDIX FAMILY
PROTEIN
(Listeria
innocua) 		4 / 7 ARG A 110
ALA A  68
ILE A  31
LEU A 163
 GOL  A 186 (-2.8A)
None
None
None
 0.93A 5te8C-3i9xA:
undetectable		 5te8C-3i9xA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 3i9x MUTT/NUDIX FAMILY
PROTEIN
(Listeria
innocua) 		3 / 3 ARG A  51
PHE A  73
ARG A 113
 None
 0.93A 5y9yA-3i9xA:
undetectable		 5y9yA-3i9xA:
22.57