SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3i9y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3004_1
(SERUM ALBUMIN)		 3i9y SENSOR PROTEIN
(Vibrio
parahaemolyticus) 		4 / 7 ALA A 216
GLU A 158
LEU A 212
MET A 249
 None
 0.91A 1hk2A-3i9yA:
undetectable		 1hk2A-3i9yA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KB9_A_PCFA514_0
(CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN
UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
CORE PROTEIN I
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 3i9y SENSOR PROTEIN
(Vibrio
parahaemolyticus) 		4 / 8 ILE A 238
VAL A 147
MET A 150
SER A 154
 None
 0.92A 1kb9A-3i9yA:
undetectable
1kb9C-3i9yA:
4.4
1kb9D-3i9yA:
undetectable
1kb9E-3i9yA:
undetectable		 1kb9A-3i9yA:
21.36
1kb9C-3i9yA:
21.86
1kb9D-3i9yA:
19.64
1kb9E-3i9yA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_A_LEIA16_0
(COIL SER L16D-PEN)		 3i9y SENSOR PROTEIN
(Vibrio
parahaemolyticus) 		4 / 6 GLN A 159
LEU A 157
GLU A 156
LEU A 268
 None
 0.90A 3h5gA-3i9yA:
undetectable
3h5gC-3i9yA:
undetectable		 3h5gA-3i9yA:
10.09
3h5gC-3i9yA:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 3i9y SENSOR PROTEIN
(Vibrio
parahaemolyticus) 		5 / 12 LEU A 126
GLU A 128
LEU A 295
ILE A  65
LEU A  72
 None
 1.28A 3olsB-3i9yA:
undetectable		 3olsB-3i9yA:
25.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V02_R_657R201_0
(CALMODULIN-1
SMALL CONDUCTANCE
CALCIUM-ACTIVATED
POTASSIUM CHANNEL
PROTEIN 2)		 3i9y SENSOR PROTEIN
(Vibrio
parahaemolyticus) 		5 / 10 LEU A 313
VAL A 314
LEU A 115
VAL A  58
ILE A  99
 None
 1.07A 5v02B-3i9yA:
4.2
5v02R-3i9yA:
undetectable		 5v02B-3i9yA:
18.84
5v02R-3i9yA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6M_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3i9y SENSOR PROTEIN
(Vibrio
parahaemolyticus) 		5 / 11 ILE A  66
LEU A 306
PHE A 303
LEU A 126
ILE A  65
 None
 1.04A 5z6mA-3i9yA:
undetectable		 5z6mA-3i9yA:
18.51