SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ia0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_A_SAMA3142_0
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)
3ia0 ETHANOLAMINE
UTILIZATION PROTEIN
EUTS

(Escherichia
coli)
5 / 12 PRO A  12
THR A  51
GLY A  49
ASP A  71
SER A  74
None
1.22A 1wg8A-3ia0A:
undetectable
1wg8A-3ia0A:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_3
(PROTEASE)
3ia0 ETHANOLAMINE
UTILIZATION PROTEIN
EUTS

(Escherichia
coli)
5 / 12 GLY A  84
ILE A  22
GLY A  42
ILE A  79
PRO A  36
None
0.97A 2nnkB-3ia0A:
undetectable
2nnkB-3ia0A:
25.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW4_A_TICA600_1
(CYTOCHROME P450 2B4)
3ia0 ETHANOLAMINE
UTILIZATION PROTEIN
EUTS

(Escherichia
coli)
5 / 11 ILE A  33
ALA A  40
ILE A  79
VAL A  78
GLY A  68
None
0.95A 3kw4A-3ia0A:
undetectable
3kw4A-3ia0A:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_1
(PROTEASE)
3ia0 ETHANOLAMINE
UTILIZATION PROTEIN
EUTS

(Escherichia
coli)
5 / 12 GLY A  84
ALA A  85
ASP A  64
ILE A  41
ILE A  79
None
1.12A 3n3iA-3ia0A:
undetectable
3n3iA-3ia0A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_SALB900_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
3ia0 ETHANOLAMINE
UTILIZATION PROTEIN
EUTS

(Escherichia
coli)
4 / 5 LEU A 100
TYR A 103
ILE A  54
ALA A  55
None
0.99A 3n8yB-3ia0A:
undetectable
3n8yB-3ia0A:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_2
(PROTEASE)
3ia0 ETHANOLAMINE
UTILIZATION PROTEIN
EUTS

(Escherichia
coli)
5 / 12 GLY A  84
ILE A  22
GLY A  42
ILE A  79
PRO A  36
None
0.94A 3nduD-3ia0A:
undetectable
3nduD-3ia0A:
25.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_1
(PROTEASE)
3ia0 ETHANOLAMINE
UTILIZATION PROTEIN
EUTS

(Escherichia
coli)
5 / 12 GLY A  84
ILE A  22
GLY A  42
ILE A  79
PRO A  36
None
1.05A 3ndxA-3ia0A:
undetectable
3ndxA-3ia0A:
25.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)
3ia0 ETHANOLAMINE
UTILIZATION PROTEIN
EUTS

(Escherichia
coli)
4 / 6 ALA A  23
GLY A  84
LEU A  21
VAL A  86
None
0.86A 4dubB-3ia0A:
undetectable
4dubB-3ia0A:
14.41