SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3iac'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_C_PPFC413_1
(PHOSPHONOACETATE
HYDROLASE)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		4 / 8 THR A 158
ASP A 239
HIS A 299
HIS A  33
 None
 0.99A 1ei6C-3iacA:
undetectable		 1ei6C-3iacA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_D_PPFD412_1
(PHOSPHONOACETATE
HYDROLASE)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		4 / 8 THR A 158
ASP A 239
HIS A 299
HIS A  33
 None
 0.94A 1ei6D-3iacA:
undetectable		 1ei6D-3iacA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UHO_A_VDNA1000_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		5 / 10 TYR A 351
HIS A 299
LEU A 332
MET A 364
GLY A 366
 None
 1.43A 1uhoA-3iacA:
undetectable		 1uhoA-3iacA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_B_URFB999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		4 / 7 MET A 147
ILE A 179
ILE A  41
ASP A  44
 None
 0.87A 1upfB-3iacA:
undetectable		 1upfB-3iacA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		3 / 3 LYS A 192
ASP A 317
ASP A  58
 None
 1.15A 2br4A-3iacA:
undetectable		 2br4A-3iacA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_A_SCKA901_1
(ACETYLCHOLINESTERASE)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		4 / 8 ASP A 387
TRP A 384
TYR A  60
HIS A  59
 None
 1.00A 2ha2A-3iacA:
undetectable		 2ha2A-3iacA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_B_SCKB951_1
(ACETYLCHOLINESTERASE)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		4 / 8 ASP A 387
TRP A 384
TYR A  60
HIS A  59
 None
 1.00A 2ha2B-3iacA:
undetectable		 2ha2B-3iacA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		3 / 3 SER A  67
HIS A  59
ASP A 414
 None
 0.74A 2oxtA-3iacA:
undetectable		 2oxtA-3iacA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		5 / 12 HIS A  35
ASP A 321
GLY A 241
HIS A  33
ASP A 414
 None
 0.94A 2pgrA-3iacA:
5.2		 2pgrA-3iacA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0J_A_BEZA500_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		5 / 10 ASP A 239
ASP A 414
LEU A 412
PHE A  32
HIS A 299
 None
 1.49A 2q0jA-3iacA:
undetectable		 2q0jA-3iacA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_C_X2NC1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		5 / 12 MET A 296
VAL A 377
THR A 279
LEU A 335
MET A 339
 None
 1.30A 2x2nC-3iacA:
undetectable		 2x2nC-3iacA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		5 / 12 THR A 278
HIS A 240
LEU A 245
LEU A 285
TYR A 289
 None
 1.31A 3gwxB-3iacA:
undetectable		 3gwxB-3iacA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_A_486A3_1
(GLUCOCORTICOID
RECEPTOR)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		5 / 12 MET A 339
LEU A 345
GLN A 369
MET A 364
LEU A 332
 None
 1.36A 3h52A-3iacA:
undetectable		 3h52A-3iacA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_B_ACRB820_1
(ALPHA-AMYLASE, SUSG)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		4 / 7 TYR A  86
GLU A 126
TRP A 129
ASN A  49
 None
 1.41A 3k8mB-3iacA:
6.1		 3k8mB-3iacA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_1
(CYTOCHROME P450 3A4)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		5 / 12 LEU A 399
PHE A 408
ILE A 349
PHE A 379
GLY A 391
 None
 1.06A 3nxuA-3iacA:
undetectable		 3nxuA-3iacA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T01_A_PPFA503_1
(PHOSPHONOACETATE
HYDROLASE)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		4 / 7 THR A 158
ASP A 239
HIS A 299
HIS A  33
 None
 0.95A 3t01A-3iacA:
undetectable		 3t01A-3iacA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_1
(PUTATIVE REGULATORY
PROTEIN)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		3 / 3 TYR A 466
MET A 364
LEU A 336
 None
 1.01A 3vw1D-3iacA:
undetectable		 3vw1D-3iacA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD392_1
(TETX2 PROTEIN)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		4 / 5 HIS A  33
SER A 184
GLN A 297
SER A 238
 None
 1.15A 4a99D-3iacA:
undetectable		 4a99D-3iacA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		4 / 7 ASP A 387
ASP A  58
ASP A  31
GLU A 108
 None
 1.18A 4feuB-3iacA:
undetectable		 4feuB-3iacA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		4 / 8 ASP A 387
ASP A  58
ASP A  31
GLU A 108
 None
 1.12A 4feuF-3iacA:
undetectable		 4feuF-3iacA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		4 / 7 ASP A 387
ASP A  58
ASP A  31
GLU A 108
 None
 1.16A 4fevD-3iacA:
undetectable		 4fevD-3iacA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		4 / 7 ASP A 387
ASP A  58
ASP A  31
GLU A 108
 None
 1.15A 4fevF-3iacA:
undetectable		 4fevF-3iacA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		4 / 8 ASP A 387
ASP A  58
ASP A  31
GLU A 108
 None
 1.16A 4fewD-3iacA:
undetectable		 4fewD-3iacA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		4 / 8 ASP A 387
ASP A  58
ASP A  31
GLU A 108
 None
 1.14A 4fewF-3iacA:
undetectable		 4fewF-3iacA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEX_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		4 / 7 ASP A 387
ASP A  58
ASP A  31
GLU A 108
 None
 1.13A 4fexB-3iacA:
undetectable		 4fexB-3iacA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		4 / 8 ASP A 387
ASP A  58
ASP A  31
GLU A 108
 None
 1.05A 4gkhB-3iacA:
undetectable		 4gkhB-3iacA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		4 / 8 ASP A 387
ASP A  58
ASP A  31
GLU A 108
 None
 1.14A 4gkhF-3iacA:
undetectable		 4gkhF-3iacA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		4 / 7 ASP A 387
ASP A  58
ASP A  31
GLU A 108
 None
 1.15A 4gkhG-3iacA:
undetectable		 4gkhG-3iacA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		4 / 8 ASP A 387
ASP A  58
ASP A  31
GLU A 108
 None
 1.13A 4gkhC-3iacA:
undetectable
4gkhK-3iacA:
undetectable		 4gkhC-3iacA:
22.27
4gkhK-3iacA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		4 / 8 ASP A 387
ASP A  58
ASP A  31
GLU A 108
 None
 1.12A 4gkiA-3iacA:
undetectable		 4gkiA-3iacA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		4 / 8 ASP A 387
ASP A  58
ASP A  31
GLU A 108
 None
 1.00A 4gkiC-3iacA:
undetectable		 4gkiC-3iacA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		4 / 8 ASP A 387
ASP A  58
ASP A  31
GLU A 108
 None
 1.12A 4gkiE-3iacA:
undetectable
4gkiG-3iacA:
undetectable		 4gkiE-3iacA:
22.27
4gkiG-3iacA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HOJ_A_ACTA303_0
(REGF PROTEIN)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		4 / 5 VAL A 283
ARG A 287
MET A 339
GLU A 344
 None
 1.43A 4hojA-3iacA:
undetectable		 4hojA-3iacA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC3_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		4 / 5 LEU A 393
LEU A 434
MET A 411
GLN A 388
 None
 1.42A 5uc3A-3iacA:
undetectable		 5uc3A-3iacA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_B_9SCB601_1
(SERUM ALBUMIN)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		4 / 6 CYH A 459
PHE A 427
LEU A 435
SER A 400
 None
 1.20A 6a7pB-3iacA:
undetectable		 6a7pB-3iacA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		3 / 3 LEU A 396
GLY A 382
PHE A  32
 None
 0.52A 6exiC-3iacA:
undetectable		 6exiC-3iacA:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA204_0
(N-ACETYLTRANSFERASE)		 3iac GLUCURONATE
ISOMERASE
(Salmonella
enterica) 		4 / 5 LEU A  74
THR A  80
THR A  76
GLY A  77
 None
 1.16A 6gtqA-3iacA:
undetectable		 6gtqA-3iacA:
15.82