SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ial'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3009_0
(BETA-CARBONIC
ANHYDRASE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		4 / 5 GLY A 482
LEU A 483
THR A 465
VAL A 253
 None
 1.11A 1ekjF-3ialA:
undetectable
1ekjG-3ialA:
undetectable		 1ekjF-3ialA:
19.01
1ekjG-3ialA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_A_NIOA221_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		4 / 6 SER A 247
PHE A 241
PHE A 272
GLY A 243
 GOL  A 602 ( 4.3A)
PR8  A 601 ( 4.1A)
None
None
 1.15A 1icuA-3ialA:
1.8
1icuB-3ialA:
1.8		 1icuA-3ialA:
17.53
1icuB-3ialA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_D_NIOD223_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		4 / 5 PHE A 272
GLY A 243
SER A 247
PHE A 241
 None
None
GOL  A 602 ( 4.3A)
PR8  A 601 ( 4.1A)
 1.17A 1icuC-3ialA:
1.8
1icuD-3ialA:
2.1		 1icuC-3ialA:
17.53
1icuD-3ialA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_B_NIOB702_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		4 / 5 PHE A 272
GLY A 243
SER A 247
PHE A 241
 None
None
GOL  A 602 ( 4.3A)
PR8  A 601 ( 4.1A)
 1.24A 1icvA-3ialA:
2.1
1icvB-3ialA:
undetectable		 1icvA-3ialA:
17.53
1icvB-3ialA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IEP_B_STIB202_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		4 / 7 VAL A 326
VAL A 392
ILE A 366
LEU A 397
 None
 0.84A 1iepB-3ialA:
undetectable		 1iepB-3ialA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWI_A_CAMA418_0
(CYTOCHROME P450-CAM)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		4 / 8 VAL A 464
VAL A 259
ASP A 251
VAL A 253
 None
 0.89A 1iwiA-3ialA:
undetectable		 1iwiA-3ialA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		4 / 7 PHE A  52
PHE A  48
MET A 254
VAL A 253
 None
 1.04A 1wrlA-3ialA:
undetectable
1wrlB-3ialA:
undetectable		 1wrlA-3ialA:
10.81
1wrlB-3ialA:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		4 / 6 TYR A 291
GLY A 269
ASP A 245
ASN A 267
 None
 1.28A 2g72A-3ialA:
undetectable		 2g72A-3ialA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IJ7_A_TPFA2472_1
(CYTOCHROME P450 121)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		5 / 11 VAL A 189
THR A 299
ALA A 303
SER A 307
PHE A  48
 PR8  A 601 (-4.2A)
None
None
None
None
 1.42A 2ij7A-3ialA:
undetectable		 2ij7A-3ialA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IJ7_D_TPFD2473_1
(CYTOCHROME P450 121)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		5 / 10 VAL A 189
THR A 299
ALA A 303
SER A 307
PHE A  48
 PR8  A 601 (-4.2A)
None
None
None
None
 1.38A 2ij7D-3ialA:
undetectable		 2ij7D-3ialA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA801_1
(TRANSPORTER)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		5 / 11 LEU A 383
ARG A 407
ILE A  55
PHE A  39
ASP A 311
 None
 0.99A 2q6hA-3ialA:
undetectable		 2q6hA-3ialA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		5 / 12 LEU A 383
ARG A 407
ILE A  55
PHE A  39
ASP A 311
 None
 1.02A 2qb4A-3ialA:
undetectable		 2qb4A-3ialA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA801_1
(TRANSPORTER)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		5 / 11 LEU A 383
ARG A 407
ILE A  55
PHE A  39
ASP A 311
 None
 1.00A 2qeiA-3ialA:
undetectable		 2qeiA-3ialA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QJU_A_DSMA801_1
(TRANSPORTER)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		5 / 11 LEU A 383
ARG A 407
ILE A  55
PHE A  39
ASP A 311
 None
 1.10A 2qjuA-3ialA:
undetectable		 2qjuA-3ialA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_D_SAMD603_0
(HYPOTHETICAL PROTEIN)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		5 / 12 GLY A 257
GLY A 481
ALA A 484
LEU A 483
PHE A  48
 None
 1.14A 2yvlD-3ialA:
undetectable		 2yvlD-3ialA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		5 / 12 GLY A 481
ALA A 539
LEU A 483
PRO A 255
PHE A 459
 None
None
None
GOL  A 604 (-4.3A)
GOL  A 604 ( 4.2A)
 1.04A 2zulA-3ialA:
undetectable		 2zulA-3ialA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWW_A_SFXA801_1
(TRANSPORTER)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		6 / 12 GLY A 385
LEU A 383
ARG A 407
ILE A  55
PHE A  39
ASP A 311
 None
 1.21A 3gwwA-3ialA:
undetectable		 3gwwA-3ialA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		4 / 7 VAL A 404
LEU A 356
ASN A 439
ILE A 352
 None
 0.95A 3rfmA-3ialA:
undetectable		 3rfmA-3ialA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TPX_E_ACTE204_0
(E3 UBIQUITIN-PROTEIN
LIGASE MDM2)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		3 / 3 LYS A 184
PRO A 185
LEU A 186
 None
 0.74A 3tpxE-3ialA:
undetectable		 3tpxE-3ialA:
9.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AWU_A_4CHA502_0
(OXIDOREDUCTASE,
FMN-BINDING)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		4 / 7 THR A 146
TYR A 152
LEU A 268
PHE A 122
 PR8  A 601 (-4.0A)
None
None
None
 1.23A 4awuA-3ialA:
undetectable		 4awuA-3ialA:
21.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4HVC_A_HFGA1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		6 / 12 GLU A 125
PRO A 145
TRP A 194
GLU A 196
HIS A 198
GLY A 296
 None
None
None
PR8  A 601 (-4.5A)
PR8  A 601 ( 4.5A)
PR8  A 601 (-3.4A)
 0.41A 4hvcA-3ialA:
43.1		 4hvcA-3ialA:
32.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4HVC_A_HFGA1602_1
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		4 / 4 THR A 146
GLU A 148
ARG A 177
HIS A 266
 PR8  A 601 (-4.0A)
PR8  A 601 (-3.0A)
PR8  A 601 ( 4.3A)
PR8  A 601 ( 3.9A)
 0.30A 4hvcA-3ialA:
43.1		 4hvcA-3ialA:
32.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4HVC_B_HFGB1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		7 / 12 LEU A 112
GLU A 125
PRO A 145
TRP A 194
GLU A 196
HIS A 198
GLY A 296
 None
None
None
None
PR8  A 601 (-4.5A)
PR8  A 601 ( 4.5A)
PR8  A 601 (-3.4A)
 0.42A 4hvcB-3ialA:
43.4		 4hvcB-3ialA:
32.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4HVC_B_HFGB1602_1
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		4 / 5 THR A 146
GLU A 148
ARG A 177
HIS A 266
 PR8  A 601 (-4.0A)
PR8  A 601 (-3.0A)
PR8  A 601 ( 4.3A)
PR8  A 601 ( 3.9A)
 0.28A 4hvcB-3ialA:
43.4		 4hvcB-3ialA:
32.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K88_A_HFGA602_0
(PROLINE--TRNA LIGASE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		7 / 12 PRO A 145
THR A 146
GLU A 148
ARG A 177
TRP A 194
GLU A 196
HIS A 266
 None
PR8  A 601 (-4.0A)
PR8  A 601 (-3.0A)
PR8  A 601 ( 4.3A)
None
PR8  A 601 (-4.5A)
PR8  A 601 ( 3.9A)
 0.47A 4k88A-3ialA:
42.3		 4k88A-3ialA:
32.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_2
(BLUE-LIGHT
PHOTORECEPTOR)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		5 / 9 MET A  56
ILE A 321
LEU A 317
ILE A  85
GLY A  78
 None
 1.03A 4kukA-3ialA:
undetectable		 4kukA-3ialA:
13.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OLF_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		6 / 12 GLU A 125
PRO A 145
TRP A 194
GLU A 196
HIS A 198
GLY A 296
 None
None
None
PR8  A 601 (-4.5A)
PR8  A 601 ( 4.5A)
PR8  A 601 (-3.4A)
 0.45A 4olfA-3ialA:
43.8		 4olfA-3ialA:
33.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OLF_A_HFGA802_1
(PROLINE--TRNA LIGASE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		4 / 4 THR A 146
GLU A 148
ARG A 177
HIS A 266
 PR8  A 601 (-4.0A)
PR8  A 601 (-3.0A)
PR8  A 601 ( 4.3A)
PR8  A 601 ( 3.9A)
 0.35A 4olfA-3ialA:
43.8		 4olfA-3ialA:
33.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Q15_A_HFGA803_0
(PROLINE--TRNA LIGASE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		5 / 12 LEU A 112
GLU A 125
PRO A 145
ARG A 177
GLY A 264
 None
None
None
PR8  A 601 ( 4.3A)
PR8  A 601 (-3.5A)
 1.05A 4q15A-3ialA:
43.2		 4q15A-3ialA:
33.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Q15_A_HFGA803_0
(PROLINE--TRNA LIGASE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		8 / 12 LEU A 112
GLU A 125
PRO A 145
THR A 146
ARG A 177
TRP A 194
HIS A 198
GLY A 296
 None
None
None
PR8  A 601 (-4.0A)
PR8  A 601 ( 4.3A)
None
PR8  A 601 ( 4.5A)
PR8  A 601 (-3.4A)
 0.47A 4q15A-3ialA:
43.2		 4q15A-3ialA:
33.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Q15_B_HFGB803_0
(PROLINE--TRNA LIGASE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		5 / 12 LEU A 112
GLU A 125
PRO A 145
ARG A 177
GLY A 264
 None
None
None
PR8  A 601 ( 4.3A)
PR8  A 601 (-3.5A)
 1.09A 4q15B-3ialA:
43.1		 4q15B-3ialA:
33.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Q15_B_HFGB803_0
(PROLINE--TRNA LIGASE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		8 / 12 LEU A 112
GLU A 125
PRO A 145
THR A 146
ARG A 177
TRP A 194
GLU A 196
GLY A 296
 None
None
None
PR8  A 601 (-4.0A)
PR8  A 601 ( 4.3A)
None
PR8  A 601 (-4.5A)
PR8  A 601 (-3.4A)
 0.47A 4q15B-3ialA:
43.1		 4q15B-3ialA:
33.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_C_CHDC102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		4 / 7 GLU A  60
LEU A 315
ARG A 407
LEU A 317
 None
 0.78A 4wg0B-3ialA:
undetectable
4wg0C-3ialA:
undetectable		 4wg0B-3ialA:
2.49
4wg0C-3ialA:
2.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YDQ_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		7 / 12 LEU A 112
GLU A 125
PRO A 145
ARG A 177
GLU A 196
HIS A 198
GLY A 296
 None
None
None
PR8  A 601 ( 4.3A)
PR8  A 601 (-4.5A)
PR8  A 601 ( 4.5A)
PR8  A 601 (-3.4A)
 0.54A 4ydqA-3ialA:
43.3		 4ydqA-3ialA:
32.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YDQ_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		5 / 12 LEU A 112
GLU A 125
PRO A 145
ARG A 177
GLY A 264
 None
None
None
PR8  A 601 ( 4.3A)
PR8  A 601 (-3.5A)
 1.15A 4ydqA-3ialA:
43.3		 4ydqA-3ialA:
32.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YDQ_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		5 / 12 LEU A 112
GLU A 196
HIS A 198
PHE A 241
GLY A 296
 None
PR8  A 601 (-4.5A)
PR8  A 601 ( 4.5A)
PR8  A 601 ( 4.1A)
PR8  A 601 (-3.4A)
 0.85A 4ydqA-3ialA:
43.3		 4ydqA-3ialA:
32.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YDQ_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		5 / 12 LEU A 112
PRO A 145
ARG A 177
TRP A 194
GLY A 296
 None
None
PR8  A 601 ( 4.3A)
None
PR8  A 601 (-3.4A)
 0.79A 4ydqA-3ialA:
43.3		 4ydqA-3ialA:
32.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YDQ_B_HFGB802_0
(PROLINE--TRNA LIGASE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		7 / 12 GLU A 125
PRO A 145
THR A 146
ARG A 177
GLU A 196
HIS A 198
GLY A 296
 None
None
PR8  A 601 (-4.0A)
PR8  A 601 ( 4.3A)
PR8  A 601 (-4.5A)
PR8  A 601 ( 4.5A)
PR8  A 601 (-3.4A)
 0.62A 4ydqB-3ialA:
43.3		 4ydqB-3ialA:
32.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YDQ_B_HFGB802_0
(PROLINE--TRNA LIGASE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		6 / 12 PRO A 145
THR A 146
ARG A 177
TRP A 194
HIS A 198
GLY A 296
 None
PR8  A 601 (-4.0A)
PR8  A 601 ( 4.3A)
None
PR8  A 601 ( 4.5A)
PR8  A 601 (-3.4A)
 0.83A 4ydqB-3ialA:
43.3		 4ydqB-3ialA:
32.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YDQ_B_HFGB802_0
(PROLINE--TRNA LIGASE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		5 / 12 PRO A 145
THR A 146
GLU A 196
HIS A 198
PHE A 272
 None
PR8  A 601 (-4.0A)
PR8  A 601 (-4.5A)
PR8  A 601 ( 4.5A)
None
 1.37A 4ydqB-3ialA:
43.3		 4ydqB-3ialA:
32.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		5 / 11 SER A 147
THR A 146
ALA A 295
GLY A 296
CYH A 173
 None
PR8  A 601 (-4.0A)
None
PR8  A 601 (-3.4A)
None
 1.07A 5bxnV-3ialA:
undetectable
5bxnW-3ialA:
undetectable		 5bxnV-3ialA:
20.04
5bxnW-3ialA:
19.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5F9Z_A_HFGA702_0
(AMINOACYL-TRNA
SYNTHETASE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		5 / 12 GLY A 121
GLU A 125
ARG A 177
SER A 247
GLY A 264
 None
None
PR8  A 601 ( 4.3A)
GOL  A 602 ( 4.3A)
PR8  A 601 (-3.5A)
 1.30A 5f9zA-3ialA:
42.2		 5f9zA-3ialA:
34.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5F9Z_A_HFGA702_0
(AMINOACYL-TRNA
SYNTHETASE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		5 / 12 LEU A 112
GLY A 121
GLU A 125
ARG A 177
PHE A 241
 None
None
None
PR8  A 601 ( 4.3A)
PR8  A 601 ( 4.1A)
 1.20A 5f9zA-3ialA:
42.2		 5f9zA-3ialA:
34.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5F9Z_A_HFGA702_0
(AMINOACYL-TRNA
SYNTHETASE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		6 / 12 LEU A 112
GLY A 121
GLU A 125
PRO A 145
ARG A 177
GLY A 264
 None
None
None
None
PR8  A 601 ( 4.3A)
PR8  A 601 (-3.5A)
 1.19A 5f9zA-3ialA:
42.2		 5f9zA-3ialA:
34.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5F9Z_A_HFGA702_0
(AMINOACYL-TRNA
SYNTHETASE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		8 / 12 LEU A 112
GLY A 121
GLU A 125
PRO A 145
ARG A 177
TRP A 194
GLU A 196
GLY A 296
 None
None
None
None
PR8  A 601 ( 4.3A)
None
PR8  A 601 (-4.5A)
PR8  A 601 (-3.4A)
 0.71A 5f9zA-3ialA:
42.2		 5f9zA-3ialA:
34.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5F9Z_B_HFGB703_0
(AMINOACYL-TRNA
SYNTHETASE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		5 / 12 LEU A 112
GLU A 125
ARG A 177
GLU A 196
PHE A 241
 None
None
PR8  A 601 ( 4.3A)
PR8  A 601 (-4.5A)
PR8  A 601 ( 4.1A)
 0.90A 5f9zB-3ialA:
42.6		 5f9zB-3ialA:
34.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5F9Z_B_HFGB703_0
(AMINOACYL-TRNA
SYNTHETASE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		5 / 12 LEU A 112
GLU A 125
PRO A 145
ARG A 177
GLY A 264
 None
None
None
PR8  A 601 ( 4.3A)
PR8  A 601 (-3.5A)
 1.01A 5f9zB-3ialA:
42.6		 5f9zB-3ialA:
34.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5F9Z_B_HFGB703_0
(AMINOACYL-TRNA
SYNTHETASE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		7 / 12 LEU A 112
GLU A 125
PRO A 145
ARG A 177
TRP A 194
GLU A 196
GLY A 296
 None
None
None
PR8  A 601 ( 4.3A)
None
PR8  A 601 (-4.5A)
PR8  A 601 (-3.4A)
 0.38A 5f9zB-3ialA:
42.6		 5f9zB-3ialA:
34.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		5 / 12 LEU A 383
GLY A 314
GLY A 313
LEU A  61
MET A  81
 None
 1.10A 5uc1A-3ialA:
undetectable		 5uc1A-3ialA:
9.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_2
(GLUCOCORTICOID
RECEPTOR)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		5 / 12 LEU A 383
GLY A 314
GLY A 313
LEU A  61
MET A  81
 None
 1.09A 5uc1B-3ialA:
undetectable		 5uc1B-3ialA:
9.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIO_A_HFGA801_0
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		6 / 12 PRO A 145
ARG A 177
TRP A 194
GLU A 196
HIS A 198
GLY A 296
 None
PR8  A 601 ( 4.3A)
None
PR8  A 601 (-4.5A)
PR8  A 601 ( 4.5A)
PR8  A 601 (-3.4A)
 0.28A 5xioA-3ialA:
42.2		 5xioA-3ialA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIO_A_HFGA801_1
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		3 / 3 THR A 146
GLU A 148
HIS A 266
 PR8  A 601 (-4.0A)
PR8  A 601 (-3.0A)
PR8  A 601 ( 3.9A)
 0.31A 5xioA-3ialA:
42.2		 5xioA-3ialA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIO_B_HFGB802_0
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		7 / 12 PRO A 145
THR A 146
ARG A 177
TRP A 194
GLU A 196
HIS A 198
HIS A 266
 None
PR8  A 601 (-4.0A)
PR8  A 601 ( 4.3A)
None
PR8  A 601 (-4.5A)
PR8  A 601 ( 4.5A)
PR8  A 601 ( 3.9A)
 0.34A 5xioB-3ialA:
42.3		 5xioB-3ialA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIP_A_HFGA1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		6 / 12 LEU A 112
GLU A 125
ARG A 177
HIS A 198
PHE A 241
GLY A 296
 None
None
PR8  A 601 ( 4.3A)
PR8  A 601 ( 4.5A)
PR8  A 601 ( 4.1A)
PR8  A 601 (-3.4A)
 0.94A 5xipA-3ialA:
42.8		 5xipA-3ialA:
32.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIP_A_HFGA1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		5 / 12 LEU A 112
GLU A 125
PRO A 145
ARG A 177
GLY A 264
 None
None
None
PR8  A 601 ( 4.3A)
PR8  A 601 (-3.5A)
 1.08A 5xipA-3ialA:
42.8		 5xipA-3ialA:
32.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIP_A_HFGA1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		7 / 12 LEU A 112
GLU A 125
PRO A 145
THR A 146
ARG A 177
HIS A 198
GLY A 296
 None
None
None
PR8  A 601 (-4.0A)
PR8  A 601 ( 4.3A)
PR8  A 601 ( 4.5A)
PR8  A 601 (-3.4A)
 0.55A 5xipA-3ialA:
42.8		 5xipA-3ialA:
32.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIP_A_HFGA1003_1
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		3 / 3 GLU A 148
TRP A 194
HIS A 266
 PR8  A 601 (-3.0A)
None
PR8  A 601 ( 3.9A)
 0.35A 5xipA-3ialA:
42.8		 5xipA-3ialA:
32.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIP_B_HFGB1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		8 / 12 GLU A 125
PRO A 145
THR A 146
GLU A 148
ARG A 177
TRP A 194
HIS A 198
HIS A 266
 None
None
PR8  A 601 (-4.0A)
PR8  A 601 (-3.0A)
PR8  A 601 ( 4.3A)
None
PR8  A 601 ( 4.5A)
PR8  A 601 ( 3.9A)
 0.55A 5xipB-3ialA:
42.6		 5xipB-3ialA:
32.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIP_B_HFGB1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		5 / 12 GLU A 148
ARG A 177
HIS A 198
PHE A 241
HIS A 266
 PR8  A 601 (-3.0A)
PR8  A 601 ( 4.3A)
PR8  A 601 ( 4.5A)
PR8  A 601 ( 4.1A)
PR8  A 601 ( 3.9A)
 0.86A 5xipB-3ialA:
42.6		 5xipB-3ialA:
32.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIP_C_HFGC1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		7 / 12 LEU A 112
GLU A 125
GLU A 148
GLU A 196
HIS A 198
PHE A 241
GLY A 296
 None
None
PR8  A 601 (-3.0A)
PR8  A 601 (-4.5A)
PR8  A 601 ( 4.5A)
PR8  A 601 ( 4.1A)
PR8  A 601 (-3.4A)
 0.81A 5xipC-3ialA:
42.3		 5xipC-3ialA:
32.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIP_C_HFGC1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		5 / 12 LEU A 112
GLU A 125
PRO A 145
GLU A 148
GLY A 264
 None
None
None
PR8  A 601 (-3.0A)
PR8  A 601 (-3.5A)
 1.22A 5xipC-3ialA:
42.3		 5xipC-3ialA:
32.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIP_C_HFGC1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		9 / 12 LEU A 112
GLU A 125
PRO A 145
THR A 146
GLU A 148
TRP A 194
GLU A 196
HIS A 198
GLY A 296
 None
None
None
PR8  A 601 (-4.0A)
PR8  A 601 (-3.0A)
None
PR8  A 601 (-4.5A)
PR8  A 601 ( 4.5A)
PR8  A 601 (-3.4A)
 0.39A 5xipC-3ialA:
42.3		 5xipC-3ialA:
32.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIP_D_HFGD1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		6 / 12 LEU A 112
GLU A 125
GLU A 148
ARG A 177
GLU A 196
PHE A 241
 None
None
PR8  A 601 (-3.0A)
PR8  A 601 ( 4.3A)
PR8  A 601 (-4.5A)
PR8  A 601 ( 4.1A)
 0.92A 5xipD-3ialA:
42.4		 5xipD-3ialA:
32.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIP_D_HFGD1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		8 / 12 LEU A 112
GLU A 125
PRO A 145
THR A 146
GLU A 148
ARG A 177
TRP A 194
GLU A 196
 None
None
None
PR8  A 601 (-4.0A)
PR8  A 601 (-3.0A)
PR8  A 601 ( 4.3A)
None
PR8  A 601 (-4.5A)
 0.56A 5xipD-3ialA:
42.4		 5xipD-3ialA:
32.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIQ_A_HFGA1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		7 / 12 LEU A 112
GLU A 125
PRO A 145
TRP A 194
GLU A 196
HIS A 198
GLY A 296
 None
None
None
None
PR8  A 601 (-4.5A)
PR8  A 601 ( 4.5A)
PR8  A 601 (-3.4A)
 0.45A 5xiqA-3ialA:
43.5		 5xiqA-3ialA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIQ_A_HFGA1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		4 / 4 THR A 146
GLU A 148
ARG A 177
HIS A 266
 PR8  A 601 (-4.0A)
PR8  A 601 (-3.0A)
PR8  A 601 ( 4.3A)
PR8  A 601 ( 3.9A)
 0.31A 5xiqA-3ialA:
43.5		 5xiqA-3ialA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIQ_B_HFGB1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		7 / 12 LEU A 112
GLU A 125
PRO A 145
ARG A 177
TRP A 194
GLU A 196
HIS A 198
 None
None
None
PR8  A 601 ( 4.3A)
None
PR8  A 601 (-4.5A)
PR8  A 601 ( 4.5A)
 0.50A 5xiqB-3ialA:
19.1		 5xiqB-3ialA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIQ_B_HFGB1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		3 / 3 THR A 146
GLU A 148
HIS A 266
 PR8  A 601 (-4.0A)
PR8  A 601 (-3.0A)
PR8  A 601 ( 3.9A)
 0.31A 5xiqB-3ialA:
19.1		 5xiqB-3ialA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIQ_C_HFGC1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		7 / 12 GLU A 125
PRO A 145
THR A 146
ARG A 177
TRP A 194
GLU A 196
HIS A 198
 None
None
PR8  A 601 (-4.0A)
PR8  A 601 ( 4.3A)
None
PR8  A 601 (-4.5A)
PR8  A 601 ( 4.5A)
 0.43A 5xiqC-3ialA:
43.5		 5xiqC-3ialA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIQ_C_HFGC1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		5 / 12 PRO A 145
THR A 146
GLU A 196
HIS A 198
PHE A 272
 None
PR8  A 601 (-4.0A)
PR8  A 601 (-4.5A)
PR8  A 601 ( 4.5A)
None
 1.34A 5xiqC-3ialA:
43.5		 5xiqC-3ialA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIQ_D_HFGD1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		5 / 12 LEU A 112
GLU A 125
PRO A 145
ARG A 177
GLY A 264
 None
None
None
PR8  A 601 ( 4.3A)
PR8  A 601 (-3.5A)
 1.06A 5xiqD-3ialA:
43.2		 5xiqD-3ialA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIQ_D_HFGD1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		8 / 12 LEU A 112
GLU A 125
PRO A 145
ARG A 177
TRP A 194
GLU A 196
HIS A 198
GLY A 296
 None
None
None
PR8  A 601 ( 4.3A)
None
PR8  A 601 (-4.5A)
PR8  A 601 ( 4.5A)
PR8  A 601 (-3.4A)
 0.48A 5xiqD-3ialA:
43.2		 5xiqD-3ialA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIQ_D_HFGD1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		5 / 12 LEU A 112
GLU A 196
HIS A 198
PHE A 241
GLY A 296
 None
PR8  A 601 (-4.5A)
PR8  A 601 ( 4.5A)
PR8  A 601 ( 4.1A)
PR8  A 601 (-3.4A)
 0.89A 5xiqD-3ialA:
43.2		 5xiqD-3ialA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIQ_D_HFGD1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		3 / 3 THR A 146
GLU A 148
HIS A 266
 PR8  A 601 (-4.0A)
PR8  A 601 (-3.0A)
PR8  A 601 ( 3.9A)
 0.32A 5xiqD-3ialA:
43.2		 5xiqD-3ialA:
32.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		4 / 7 HIS A 513
ASN A 514
GLU A 517
ARG A 485
 None
 1.27A 6b8kA-3ialA:
undetectable		 6b8kA-3ialA:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNK_A_NCTA405_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		4 / 6 THR A 149
CYH A 294
TYR A 152
THR A 146
 None
PR8  A 601 ( 3.8A)
None
PR8  A 601 (-4.0A)
 1.45A 6cnkA-3ialA:
0.0
6cnkB-3ialA:
0.0		 6cnkA-3ialA:
12.05
6cnkB-3ialA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		4 / 8 VAL A 464
VAL A 259
ASP A 251
VAL A 253
 None
 0.90A 6cp4A-3ialA:
undetectable		 6cp4A-3ialA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		5 / 10 LEU A 356
THR A 355
ILE A 419
ILE A 390
ILE A 328
 None
 1.10A 6ebpD-3ialA:
undetectable		 6ebpD-3ialA:
9.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MN8_A_HFGA603_0
(UNCHARACTERIZED
PROTEIN)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		7 / 12 LEU A 112
GLU A 125
PRO A 145
TRP A 194
GLU A 196
HIS A 198
GLY A 296
 None
None
None
None
PR8  A 601 (-4.5A)
PR8  A 601 ( 4.5A)
PR8  A 601 (-3.4A)
 0.44A 6mn8A-3ialA:
25.1		 6mn8A-3ialA:
33.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MN8_A_HFGA603_1
(UNCHARACTERIZED
PROTEIN)		 3ial PROLYL-TRNA
SYNTHETASE
(Giardia
intestinalis) 		4 / 4 THR A 146
GLU A 148
ARG A 177
HIS A 266
 PR8  A 601 (-4.0A)
PR8  A 601 (-3.0A)
PR8  A 601 ( 4.3A)
PR8  A 601 ( 3.9A)
 0.44A 6mn8A-3ialA:
25.1		 6mn8A-3ialA:
33.70