SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ib5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OPJ_A_STIA3_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3ib5 SEX PHEROMONE
PRECURSOR
(Lactobacillus
salivarius) 		4 / 5 TYR A 240
VAL A 246
ILE A  91
MET A 174
 None
EDO  A   3 ( 4.0A)
None
None
 1.37A 1opjA-3ib5A:
undetectable		 1opjA-3ib5A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_1
(HIV-1 PROTEASE)		 3ib5 SEX PHEROMONE
PRECURSOR
(Lactobacillus
salivarius) 		5 / 12 ALA A 206
ILE A 170
ILE A 150
GLY A 173
ILE A 225
 None
 1.02A 2hs1A-3ib5A:
undetectable		 2hs1A-3ib5A:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA803_0
(FERROCHELATASE)		 3ib5 SEX PHEROMONE
PRECURSOR
(Lactobacillus
salivarius) 		4 / 5 LEU A 343
PRO A 344
LEU A 314
ILE A 316
 None
 0.70A 2qd4A-3ib5A:
undetectable		 2qd4A-3ib5A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAX_A_CAMA422_0
(CYTOCHROME P450-CAM)		 3ib5 SEX PHEROMONE
PRECURSOR
(Lactobacillus
salivarius) 		4 / 7 PHE A 322
VAL A 335
THR A 375
VAL A 377
 None
 1.04A 2zaxA-3ib5A:
undetectable		 2zaxA-3ib5A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM9_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3ib5 SEX PHEROMONE
PRECURSOR
(Lactobacillus
salivarius) 		5 / 8 MET A 227
ALA A 226
TRP A 256
GLY A 171
ILE A 172
 None
 1.49A 2zm9A-3ib5A:
undetectable		 2zm9A-3ib5A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_1
(UNCHARACTERIZED
PROTEIN MJ1557)		 3ib5 SEX PHEROMONE
PRECURSOR
(Lactobacillus
salivarius) 		3 / 3 MET A 156
GLU A 152
ASN A 110
 None
 1.02A 3a27A-3ib5A:
undetectable		 3a27A-3ib5A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 3ib5 SEX PHEROMONE
PRECURSOR
(Lactobacillus
salivarius) 		4 / 7 PHE A 322
VAL A 335
THR A 375
VAL A 377
 None
 1.01A 3fwgB-3ib5A:
undetectable		 3fwgB-3ib5A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_A_MTXA164_2
(DIHYDROFOLATE
REDUCTASE)		 3ib5 SEX PHEROMONE
PRECURSOR
(Lactobacillus
salivarius) 		4 / 4 ILE A 353
PHE A 331
ILE A 318
THR A 375
 None
 0.96A 3ia4A-3ib5A:
undetectable		 3ia4A-3ib5A:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3ib5 SEX PHEROMONE
PRECURSOR
(Lactobacillus
salivarius) 		4 / 8 TYR A 146
VAL A 147
MET A 227
ILE A 172
 None
 0.85A 4a97C-3ib5A:
undetectable		 4a97C-3ib5A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_E_ZPCE1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3ib5 SEX PHEROMONE
PRECURSOR
(Lactobacillus
salivarius) 		4 / 8 TYR A 146
VAL A 147
MET A 227
ILE A 172
 None
 0.84A 4a97D-3ib5A:
undetectable		 4a97D-3ib5A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3ib5 SEX PHEROMONE
PRECURSOR
(Lactobacillus
salivarius) 		4 / 8 TYR A 146
VAL A 147
MET A 227
ILE A 172
 None
 0.80A 4a97G-3ib5A:
undetectable		 4a97G-3ib5A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_J_ZPCJ1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3ib5 SEX PHEROMONE
PRECURSOR
(Lactobacillus
salivarius) 		4 / 8 TYR A 146
VAL A 147
MET A 227
ILE A 172
 None
 0.81A 4a97I-3ib5A:
undetectable		 4a97I-3ib5A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 3ib5 SEX PHEROMONE
PRECURSOR
(Lactobacillus
salivarius) 		4 / 7 TYR A 101
THR A 169
VAL A 246
VAL A 224
 None
None
EDO  A   3 ( 4.0A)
None
 1.00A 4cp4A-3ib5A:
undetectable		 4cp4A-3ib5A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ib5 SEX PHEROMONE
PRECURSOR
(Lactobacillus
salivarius) 		5 / 12 ASN A  74
PHE A 228
GLY A  87
ALA A  86
SER A  83
 None
 0.96A 4e1gA-3ib5A:
undetectable		 4e1gA-3ib5A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3ib5 SEX PHEROMONE
PRECURSOR
(Lactobacillus
salivarius) 		4 / 4 LEU A 343
PRO A 344
LEU A 314
ILE A 316
 None
 0.77A 4f4dB-3ib5A:
undetectable		 4f4dB-3ib5A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_0
(METHYLTRANSFERASE
NSUN4)		 3ib5 SEX PHEROMONE
PRECURSOR
(Lactobacillus
salivarius) 		5 / 12 GLY A 372
GLY A 371
GLY A 313
PRO A 344
LEU A 311
 None
 0.97A 4fp9A-3ib5A:
undetectable		 4fp9A-3ib5A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_0
(METHYLTRANSFERASE
NSUN4)		 3ib5 SEX PHEROMONE
PRECURSOR
(Lactobacillus
salivarius) 		5 / 12 GLY A 372
GLY A 371
GLY A 313
PRO A 344
LEU A 311
 None
 0.97A 4fp9C-3ib5A:
undetectable		 4fp9C-3ib5A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_0
(METHYLTRANSFERASE
NSUN4)		 3ib5 SEX PHEROMONE
PRECURSOR
(Lactobacillus
salivarius) 		5 / 12 GLY A 372
GLY A 371
GLY A 313
PRO A 344
LEU A 311
 None
 0.97A 4fp9D-3ib5A:
undetectable		 4fp9D-3ib5A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_0
(METHYLTRANSFERASE
NSUN4)		 3ib5 SEX PHEROMONE
PRECURSOR
(Lactobacillus
salivarius) 		5 / 12 GLY A 372
GLY A 371
GLY A 313
PRO A 344
LEU A 311
 None
 0.96A 4fp9F-3ib5A:
undetectable		 4fp9F-3ib5A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_0
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 3ib5 SEX PHEROMONE
PRECURSOR
(Lactobacillus
salivarius) 		5 / 12 GLY A 372
GLY A 371
GLY A 313
PRO A 344
LEU A 311
 None
 0.98A 4fzvA-3ib5A:
undetectable		 4fzvA-3ib5A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H1N_A_CGEA505_1
(CYTOCHROME P450 2B4)		 3ib5 SEX PHEROMONE
PRECURSOR
(Lactobacillus
salivarius) 		5 / 11 ILE A 172
ILE A 170
LEU A 109
ALA A 211
ILE A 253
 None
 0.80A 4h1nA-3ib5A:
undetectable		 4h1nA-3ib5A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3ib5 SEX PHEROMONE
PRECURSOR
(Lactobacillus
salivarius) 		4 / 5 LEU A 343
PRO A 344
LEU A 314
ILE A 316
 None
 0.75A 4klrA-3ib5A:
undetectable		 4klrA-3ib5A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_2
(ASPARTYL PROTEASE)		 3ib5 SEX PHEROMONE
PRECURSOR
(Lactobacillus
salivarius) 		5 / 12 ALA A 206
ILE A 170
ILE A 150
GLY A 173
ILE A 225
 None
 1.04A 4q1yB-3ib5A:
undetectable		 4q1yB-3ib5A:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRY_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 3ib5 SEX PHEROMONE
PRECURSOR
(Lactobacillus
salivarius) 		4 / 8 GLY A 167
TYR A  52
PHE A  96
SER A  92
 None
None
EDO  A   4 (-4.4A)
None
 0.99A 4wryA-3ib5A:
undetectable		 4wryA-3ib5A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRZ_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 3ib5 SEX PHEROMONE
PRECURSOR
(Lactobacillus
salivarius) 		4 / 8 GLY A 167
TYR A  52
PHE A  96
SER A  92
 None
None
EDO  A   4 (-4.4A)
None
 1.02A 4wrzA-3ib5A:
undetectable		 4wrzA-3ib5A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS1_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 3ib5 SEX PHEROMONE
PRECURSOR
(Lactobacillus
salivarius) 		4 / 8 GLY A 167
TYR A  52
PHE A  96
SER A  92
 None
None
EDO  A   4 (-4.4A)
None
 0.97A 4ws1A-3ib5A:
undetectable		 4ws1A-3ib5A:
17.45