SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ibh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBS_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE II)		 3ibh SACCHAROMYCES
CEREVISIAE GTT2
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 125
ILE A 189
ALA A 190
THR A  24
LEU A 139
 None
 1.04A 1cbsA-3ibhA:
undetectable		 1cbsA-3ibhA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G78_A_REAA200_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 3ibh SACCHAROMYCES
CEREVISIAE GTT2
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 125
ILE A 189
ALA A 190
THR A  24
LEU A 139
 None
 1.06A 2g78A-3ibhA:
undetectable		 2g78A-3ibhA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A163_1
(BETA-LACTOGLOBULIN)		 3ibh SACCHAROMYCES
CEREVISIAE GTT2
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  83
GLU A 121
ILE A  89
ILE A  93
ALA A  36
 None
GSH  A 234 (-4.4A)
None
None
None
 1.23A 2gj5A-3ibhA:
undetectable		 2gj5A-3ibhA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_D_DVAD6_0
(GRAMICIDIN D)		 3ibh SACCHAROMYCES
CEREVISIAE GTT2
(Saccharomyces
cerevisiae) 		3 / 3 TRP A 151
ALA A 135
VAL A 130
 None
 0.96A 2izqC-3ibhA:
undetectable
2izqD-3ibhA:
undetectable		 2izqC-3ibhA:
6.58
2izqD-3ibhA:
6.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA508_0
(CHORISMATE SYNTHASE)		 3ibh SACCHAROMYCES
CEREVISIAE GTT2
(Saccharomyces
cerevisiae) 		4 / 5 LEU A  37
ARG A  34
ALA A  36
ILE A  21
 None
 1.18A 2qhfA-3ibhA:
undetectable		 2qhfA-3ibhA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_A_EPAA1_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 3ibh SACCHAROMYCES
CEREVISIAE GTT2
(Saccharomyces
cerevisiae) 		5 / 12 HIS A 133
LEU A 125
ILE A 197
ILE A 193
LEU A  53
 GSH  A 234 (-3.4A)
None
None
None
GSH  A 234 ( 4.6A)
 1.33A 3gwxA-3ibhA:
undetectable		 3gwxA-3ibhA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA502_1
(CHITINASE)		 3ibh SACCHAROMYCES
CEREVISIAE GTT2
(Saccharomyces
cerevisiae) 		4 / 5 TRP A 212
GLY A 191
ALA A 120
PHE A 181
 None
 1.37A 3wqwA-3ibhA:
undetectable		 3wqwA-3ibhA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7G_A_ACTA514_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3ibh SACCHAROMYCES
CEREVISIAE GTT2
(Saccharomyces
cerevisiae) 		4 / 4 ALA A 184
VAL A 188
ASP A 185
LEU A 170
 None
 0.86A 4e7gA-3ibhA:
undetectable		 4e7gA-3ibhA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)		 3ibh SACCHAROMYCES
CEREVISIAE GTT2
(Saccharomyces
cerevisiae) 		3 / 3 MET A 163
MET A 116
TYR A 213
 None
 1.28A 4p6xI-3ibhA:
undetectable		 4p6xI-3ibhA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB203_0
(HYDROXYNITRILE LYASE)		 3ibh SACCHAROMYCES
CEREVISIAE GTT2
(Saccharomyces
cerevisiae) 		4 / 4 VAL A 176
ALA A 120
ILE A 186
THR A 187
 None
 1.19A 5e4dB-3ibhA:
undetectable		 5e4dB-3ibhA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3ibh SACCHAROMYCES
CEREVISIAE GTT2
(Saccharomyces
cerevisiae) 		4 / 4 GLN A 147
THR A 136
LEU A  53
LEU A 139
 None
None
GSH  A 234 ( 4.6A)
None
 1.11A 5m5kB-3ibhA:
undetectable		 5m5kB-3ibhA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA511_1
(PROTON-GATED ION
CHANNEL)		 3ibh SACCHAROMYCES
CEREVISIAE GTT2
(Saccharomyces
cerevisiae) 		4 / 8 ALA A  26
ILE A 193
ALA A 196
ILE A 197
 None
 0.75A 5mvmA-3ibhA:
3.0
5mvmB-3ibhA:
2.2		 5mvmA-3ibhA:
18.53
5mvmB-3ibhA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_A_BEZA301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 3ibh SACCHAROMYCES
CEREVISIAE GTT2
(Saccharomyces
cerevisiae) 		4 / 7 ILE A  89
LEU A  75
MET A  19
LEU A  77
 None
 0.99A 5u4sA-3ibhA:
undetectable		 5u4sA-3ibhA:
22.05