SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ibm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_A_NCTA1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3ibm CUPIN 2, CONSERVED
BARREL DOMAIN
PROTEIN
(Halorhodospira
halophila) 		4 / 8 TYR A  17
TRP A  19
LEU A 124
MET A  79
 None
 1.28A 1uw6A-3ibmA:
undetectable
1uw6B-3ibmA:
undetectable		 1uw6A-3ibmA:
16.90
1uw6B-3ibmA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_D_NCTD1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3ibm CUPIN 2, CONSERVED
BARREL DOMAIN
PROTEIN
(Halorhodospira
halophila) 		4 / 8 TYR A  17
TRP A  19
LEU A 124
MET A  79
 None
 1.31A 1uw6D-3ibmA:
undetectable
1uw6E-3ibmA:
undetectable		 1uw6D-3ibmA:
16.90
1uw6E-3ibmA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_G_NCTG1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3ibm CUPIN 2, CONSERVED
BARREL DOMAIN
PROTEIN
(Halorhodospira
halophila) 		4 / 8 TYR A  17
TRP A  19
LEU A 124
MET A  79
 None
 1.33A 1uw6G-3ibmA:
undetectable
1uw6H-3ibmA:
undetectable		 1uw6G-3ibmA:
16.90
1uw6H-3ibmA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_T_NCTT1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3ibm CUPIN 2, CONSERVED
BARREL DOMAIN
PROTEIN
(Halorhodospira
halophila) 		4 / 8 TRP A  19
LEU A 124
MET A  79
TYR A  17
 None
 1.26A 1uw6P-3ibmA:
undetectable
1uw6T-3ibmA:
undetectable		 1uw6P-3ibmA:
16.90
1uw6T-3ibmA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_A_H4BA1003_1
(HYPOTHETICAL PROTEIN
PH0634)		 3ibm CUPIN 2, CONSERVED
BARREL DOMAIN
PROTEIN
(Halorhodospira
halophila) 		5 / 10 HIS A 110
HIS A  72
HIS A  76
THR A  68
THR A  67
 ZN  A 200 (-3.3A)
ZN  A 200 (-3.3A)
ZN  A 200 (-3.3A)
None
None
 1.38A 2dttA-3ibmA:
undetectable
2dttC-3ibmA:
undetectable		 2dttA-3ibmA:
20.96
2dttC-3ibmA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ibm CUPIN 2, CONSERVED
BARREL DOMAIN
PROTEIN
(Halorhodospira
halophila) 		3 / 3 HIS A  76
HIS A  72
HIS A  74
 ZN  A 200 (-3.3A)
ZN  A 200 (-3.3A)
None
 0.75A 2dysN-3ibmA:
undetectable		 2dysN-3ibmA:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YS6_A_GLYA431_0
(PHOSPHORIBOSYLGLYCIN
AMIDE SYNTHETASE)		 3ibm CUPIN 2, CONSERVED
BARREL DOMAIN
PROTEIN
(Halorhodospira
halophila) 		4 / 8 TYR A  58
GLY A 122
PRO A 120
GLU A  60
 None
 0.91A 2ys6A-3ibmA:
undetectable		 2ys6A-3ibmA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA602_0
(LACCASE-1)		 3ibm CUPIN 2, CONSERVED
BARREL DOMAIN
PROTEIN
(Halorhodospira
halophila) 		3 / 3 HIS A  72
HIS A 110
HIS A  76
 ZN  A 200 (-3.3A)
ZN  A 200 (-3.3A)
ZN  A 200 (-3.3A)
 0.45A 3qpkA-3ibmA:
undetectable		 3qpkA-3ibmA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)		 3ibm CUPIN 2, CONSERVED
BARREL DOMAIN
PROTEIN
(Halorhodospira
halophila) 		3 / 3 HIS A  72
HIS A 110
HIS A  76
 ZN  A 200 (-3.3A)
ZN  A 200 (-3.3A)
ZN  A 200 (-3.3A)
 0.43A 3qpkB-3ibmA:
undetectable		 3qpkB-3ibmA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 3ibm CUPIN 2, CONSERVED
BARREL DOMAIN
PROTEIN
(Halorhodospira
halophila) 		5 / 12 GLU A  50
SER A 129
VAL A 127
CYH A 125
LEU A 124
 None
 1.36A 4k36A-3ibmA:
undetectable		 4k36A-3ibmA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 3ibm CUPIN 2, CONSERVED
BARREL DOMAIN
PROTEIN
(Halorhodospira
halophila) 		5 / 12 SER A 129
ARG A 131
VAL A 127
CYH A 125
LEU A 124
 None
 1.21A 4k36A-3ibmA:
undetectable		 4k36A-3ibmA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_A_3CJA607_1
(LACTOPEROXIDASE)		 3ibm CUPIN 2, CONSERVED
BARREL DOMAIN
PROTEIN
(Halorhodospira
halophila) 		3 / 3 GLN A 111
HIS A 113
ARG A 154
 None
 1.04A 4qyqA-3ibmA:
undetectable		 4qyqA-3ibmA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_B_3CJB607_1
(LACTOPEROXIDASE)		 3ibm CUPIN 2, CONSERVED
BARREL DOMAIN
PROTEIN
(Halorhodospira
halophila) 		3 / 3 GLN A 111
HIS A 113
ARG A 154
 None
 0.99A 4qyqB-3ibmA:
undetectable		 4qyqB-3ibmA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0S_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3ibm CUPIN 2, CONSERVED
BARREL DOMAIN
PROTEIN
(Halorhodospira
halophila) 		5 / 12 ILE A 104
VAL A  78
VAL A  80
LEU A 121
PHE A 123
 None
 0.83A 4y0sA-3ibmA:
undetectable		 4y0sA-3ibmA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ibm CUPIN 2, CONSERVED
BARREL DOMAIN
PROTEIN
(Halorhodospira
halophila) 		5 / 12 HIS A  72
HIS A  76
VAL A  78
LEU A  89
ALA A 108
 ZN  A 200 (-3.3A)
ZN  A 200 (-3.3A)
None
None
None
 1.38A 4ygfG-3ibmA:
undetectable		 4ygfG-3ibmA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 3ibm CUPIN 2, CONSERVED
BARREL DOMAIN
PROTEIN
(Halorhodospira
halophila) 		5 / 10 HIS A 110
GLU A  70
HIS A  76
VAL A  78
THR A  67
 ZN  A 200 (-3.3A)
ZN  A 200 (-3.3A)
ZN  A 200 (-3.3A)
None
None
 1.33A 5jn8D-3ibmA:
undetectable		 5jn8D-3ibmA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA601_0
(LACCASE 2)		 3ibm CUPIN 2, CONSERVED
BARREL DOMAIN
PROTEIN
(Halorhodospira
halophila) 		3 / 3 HIS A  72
HIS A 110
HIS A  76
 ZN  A 200 (-3.3A)
ZN  A 200 (-3.3A)
ZN  A 200 (-3.3A)
 0.44A 5migA-3ibmA:
undetectable		 5migA-3ibmA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N1T_W_CUW201_0
(COPC)		 3ibm CUPIN 2, CONSERVED
BARREL DOMAIN
PROTEIN
(Halorhodospira
halophila) 		3 / 3 HIS A  72
ASP A 132
HIS A  74
 ZN  A 200 (-3.3A)
None
None
 0.83A 5n1tW-3ibmA:
undetectable		 5n1tW-3ibmA:
19.67