SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ibx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_B_SAMB2401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 3ibx PUTATIVE THIAMINASE
II
(Helicobacter
pylori) 		5 / 12 TYR A 165
GLY A  26
GLY A  28
ILE A 142
LEU A  48
 None
 1.11A 1p91B-3ibxA:
undetectable		 1p91B-3ibxA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_A_HSMA401_1
(NITROPHORIN 1)		 3ibx PUTATIVE THIAMINASE
II
(Helicobacter
pylori) 		4 / 4 ASP A  44
LEU A  49
LEU A  46
LEU A  48
 None
 1.36A 1u18A-3ibxA:
undetectable		 1u18A-3ibxA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOS_A_VIAA1_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 3ibx PUTATIVE THIAMINASE
II
(Helicobacter
pylori) 		5 / 12 TYR A 139
ASP A  44
LEU A  48
PHE A 170
ILE A  78
 None
 1.43A 1xosA-3ibxA:
undetectable		 1xosA-3ibxA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_A_SCKA901_1
(ACETYLCHOLINESTERASE)		 3ibx PUTATIVE THIAMINASE
II
(Helicobacter
pylori) 		4 / 8 TYR A  47
ASP A  44
TYR A 139
HIS A  21
 None
 1.38A 2ha2A-3ibxA:
undetectable		 2ha2A-3ibxA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_B_SCKB951_1
(ACETYLCHOLINESTERASE)		 3ibx PUTATIVE THIAMINASE
II
(Helicobacter
pylori) 		4 / 8 TYR A  47
ASP A  44
TYR A 139
HIS A  21
 None
 1.39A 2ha2B-3ibxA:
undetectable		 2ha2B-3ibxA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_A_H3PA552_1
(GLUTAMATE
DEHYDROGENASE)		 3ibx PUTATIVE THIAMINASE
II
(Helicobacter
pylori) 		4 / 6 ILE A  14
TYR A   8
ILE A  19
HIS A  21
 None
 0.87A 3eteA-3ibxA:
undetectable
3eteE-3ibxA:
undetectable		 3eteA-3ibxA:
18.04
3eteE-3ibxA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC554_1
(GLUTAMATE
DEHYDROGENASE)		 3ibx PUTATIVE THIAMINASE
II
(Helicobacter
pylori) 		4 / 5 ILE A  14
TYR A   8
ILE A  19
HIS A  21
 None
 0.89A 3eteB-3ibxA:
undetectable
3eteC-3ibxA:
undetectable		 3eteB-3ibxA:
18.04
3eteC-3ibxA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_F_H3PF552_1
(GLUTAMATE
DEHYDROGENASE)		 3ibx PUTATIVE THIAMINASE
II
(Helicobacter
pylori) 		4 / 7 ILE A  19
HIS A  21
ILE A  14
TYR A   8
 None
 0.87A 3eteD-3ibxA:
undetectable
3eteF-3ibxA:
undetectable		 3eteD-3ibxA:
18.04
3eteF-3ibxA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UZZ_A_TESA501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 3ibx PUTATIVE THIAMINASE
II
(Helicobacter
pylori) 		4 / 7 TYR A 165
HIS A  86
TYR A  47
TRP A 211
 None
 1.47A 3uzzA-3ibxA:
0.0		 3uzzA-3ibxA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_A_377A401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3ibx PUTATIVE THIAMINASE
II
(Helicobacter
pylori) 		4 / 5 GLU A 207
TYR A 112
PHE A 210
TYR A  51
 None
 1.26A 4twdA-3ibxA:
2.5
4twdE-3ibxA:
2.3		 4twdA-3ibxA:
20.50
4twdE-3ibxA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_E_377E401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3ibx PUTATIVE THIAMINASE
II
(Helicobacter
pylori) 		4 / 6 TYR A  51
GLU A 207
TYR A 112
PHE A 210
 None
 1.30A 4twdD-3ibxA:
2.7
4twdE-3ibxA:
2.3		 4twdD-3ibxA:
20.50
4twdE-3ibxA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_G_377G401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3ibx PUTATIVE THIAMINASE
II
(Helicobacter
pylori) 		4 / 6 TYR A  51
GLU A 207
TYR A 112
PHE A 210
 None
 1.27A 4twdF-3ibxA:
undetectable
4twdG-3ibxA:
undetectable		 4twdF-3ibxA:
20.50
4twdG-3ibxA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_A_PAUA602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3ibx PUTATIVE THIAMINASE
II
(Helicobacter
pylori) 		4 / 7 GLY A  58
GLY A 120
TYR A  51
ALA A  56
 None
 0.85A 5e26A-3ibxA:
undetectable
5e26B-3ibxA:
undetectable		 5e26A-3ibxA:
21.02
5e26B-3ibxA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_B_PAUB601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3ibx PUTATIVE THIAMINASE
II
(Helicobacter
pylori) 		4 / 7 TYR A  51
ALA A  56
GLY A  58
GLY A 120
 None
 0.87A 5e26A-3ibxA:
undetectable
5e26B-3ibxA:
undetectable		 5e26A-3ibxA:
21.02
5e26B-3ibxA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3ibx PUTATIVE THIAMINASE
II
(Helicobacter
pylori) 		4 / 7 GLY A  58
GLY A 120
TYR A  51
ALA A  56
 None
 0.87A 5e26C-3ibxA:
undetectable
5e26D-3ibxA:
undetectable		 5e26C-3ibxA:
21.02
5e26D-3ibxA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_D_PAUD601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3ibx PUTATIVE THIAMINASE
II
(Helicobacter
pylori) 		4 / 8 TYR A  51
ALA A  56
GLY A  58
GLY A 120
 None
 0.85A 5e26C-3ibxA:
undetectable
5e26D-3ibxA:
undetectable		 5e26C-3ibxA:
21.02
5e26D-3ibxA:
21.02