SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ibz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_C_DVAC6_0
(GRAMICIDIN A)		 3ibz PUTATIVE TELLURIUM
RESISTANT LIKE
PROTEIN TERD
(Streptomyces
coelicolor) 		3 / 3 ALA A 100
VAL A  98
TRP A 167
 None
 0.88A 1av2C-3ibzA:
undetectable
1av2D-3ibzA:
undetectable		 1av2C-3ibzA:
6.55
1av2D-3ibzA:
6.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_A_VIBA502_1
(THIAMIN
PYROPHOSPHOKINASE)		 3ibz PUTATIVE TELLURIUM
RESISTANT LIKE
PROTEIN TERD
(Streptomyces
coelicolor) 		4 / 8 LEU A 180
SER A  44
ASP A  78
THR A  76
 None
None
CA  A 192 (-3.1A)
None
 1.13A 1ig3A-3ibzA:
undetectable
1ig3B-3ibzA:
undetectable		 1ig3A-3ibzA:
21.07
1ig3B-3ibzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_A_DVAA6_0
(GRAMICIDIN C)		 3ibz PUTATIVE TELLURIUM
RESISTANT LIKE
PROTEIN TERD
(Streptomyces
coelicolor) 		3 / 3 ALA A 100
VAL A  98
TRP A 167
 None
 0.87A 1nt6A-3ibzA:
undetectable		 1nt6A-3ibzA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_B_DVAB6_0
(GRAMICIDIN C)		 3ibz PUTATIVE TELLURIUM
RESISTANT LIKE
PROTEIN TERD
(Streptomyces
coelicolor) 		3 / 3 ALA A 100
VAL A  98
TRP A 167
 None
 0.88A 1nt6B-3ibzA:
undetectable		 1nt6B-3ibzA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_A_RBFA100_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 3ibz PUTATIVE TELLURIUM
RESISTANT LIKE
PROTEIN TERD
(Streptomyces
coelicolor) 		5 / 11 LEU A  95
THR A  21
ILE A  91
ILE A  24
VAL A  25
 None
 1.25A 1pkvA-3ibzA:
undetectable
1pkvB-3ibzA:
undetectable		 1pkvA-3ibzA:
21.47
1pkvB-3ibzA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_B_RBFB101_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 3ibz PUTATIVE TELLURIUM
RESISTANT LIKE
PROTEIN TERD
(Streptomyces
coelicolor) 		5 / 11 ILE A  24
VAL A  25
LEU A  95
THR A  21
ILE A  91
 None
 1.24A 1pkvA-3ibzA:
undetectable
1pkvB-3ibzA:
undetectable		 1pkvA-3ibzA:
21.47
1pkvB-3ibzA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_A_SAMA301_1
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 3ibz PUTATIVE TELLURIUM
RESISTANT LIKE
PROTEIN TERD
(Streptomyces
coelicolor) 		3 / 3 GLY A  28
ASP A  88
ASN A 126
 CA  A 193 ( 4.9A)
CA  A 193 (-2.3A)
None
 0.62A 1vq1A-3ibzA:
undetectable		 1vq1A-3ibzA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_C_DVAC6_0
(GRAMICIDIN D)		 3ibz PUTATIVE TELLURIUM
RESISTANT LIKE
PROTEIN TERD
(Streptomyces
coelicolor) 		3 / 3 ALA A 100
VAL A  98
TRP A 167
 None
 0.85A 1w5uC-3ibzA:
undetectable
1w5uD-3ibzA:
undetectable		 1w5uC-3ibzA:
6.55
1w5uD-3ibzA:
6.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_B_DVAB6_0
(GRAMICIDIN D)		 3ibz PUTATIVE TELLURIUM
RESISTANT LIKE
PROTEIN TERD
(Streptomyces
coelicolor) 		3 / 3 TRP A 167
ALA A 100
VAL A  98
 None
 0.85A 2izqA-3ibzA:
undetectable
2izqB-3ibzA:
undetectable		 2izqA-3ibzA:
6.55
2izqB-3ibzA:
6.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_G_GCSG710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 3ibz PUTATIVE TELLURIUM
RESISTANT LIKE
PROTEIN TERD
(Streptomyces
coelicolor) 		4 / 8 TRP A 167
ARG A 162
ILE A 105
ASP A  70
 None
 1.09A 2xadC-3ibzA:
undetectable		 2xadC-3ibzA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_H_GCSH710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 3ibz PUTATIVE TELLURIUM
RESISTANT LIKE
PROTEIN TERD
(Streptomyces
coelicolor) 		4 / 8 TRP A 167
ARG A 162
ILE A 105
ASP A  70
 None
 1.08A 2xadD-3ibzA:
undetectable		 2xadD-3ibzA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZI9_A_CL9A401_2
(DEOXYCYTIDINE KINASE)		 3ibz PUTATIVE TELLURIUM
RESISTANT LIKE
PROTEIN TERD
(Streptomyces
coelicolor) 		3 / 3 ASP A  38
PHE A  39
LEU A  41
 None
 0.68A 2zi9A-3ibzA:
undetectable		 2zi9A-3ibzA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_A_DVAA6_0
(GRAMICIDIN D)		 3ibz PUTATIVE TELLURIUM
RESISTANT LIKE
PROTEIN TERD
(Streptomyces
coelicolor) 		3 / 3 ALA A 100
VAL A  98
TRP A 167
 None
 0.83A 3l8lA-3ibzA:
undetectable
3l8lB-3ibzA:
undetectable		 3l8lA-3ibzA:
6.55
3l8lB-3ibzA:
6.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_C_DVAC6_0
(GRAMICIDIN D)		 3ibz PUTATIVE TELLURIUM
RESISTANT LIKE
PROTEIN TERD
(Streptomyces
coelicolor) 		3 / 3 ALA A 100
VAL A  98
TRP A 167
 None
 0.77A 3l8lC-3ibzA:
undetectable
3l8lD-3ibzA:
undetectable		 3l8lC-3ibzA:
6.55
3l8lD-3ibzA:
6.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TI1_A_B49A299_1
(CYCLIN-DEPENDENT
KINASE 2)		 3ibz PUTATIVE TELLURIUM
RESISTANT LIKE
PROTEIN TERD
(Streptomyces
coelicolor) 		5 / 9 ALA A 127
PHE A 128
PHE A 121
ASP A  42
ASP A  88
 None
None
None
CA  A 192 (-3.2A)
CA  A 193 (-2.3A)
 1.34A 3ti1A-3ibzA:
undetectable		 3ti1A-3ibzA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_A_ADNA1002_1
(MYOSIN HEAVY CHAIN
KINASE A)		 3ibz PUTATIVE TELLURIUM
RESISTANT LIKE
PROTEIN TERD
(Streptomyces
coelicolor) 		5 / 11 PHE A 187
GLY A  51
VAL A 106
LYS A 104
GLU A 159
 None
 0.99A 4zmeA-3ibzA:
undetectable		 4zmeA-3ibzA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WY0_A_SAMA800_0
(SMALL RNA
2'-O-METHYLTRANSFERA
SE)		 3ibz PUTATIVE TELLURIUM
RESISTANT LIKE
PROTEIN TERD
(Streptomyces
coelicolor) 		6 / 12 GLY A 122
ILE A 111
SER A 110
VAL A 109
LEU A 145
LEU A  27
 None
 1.28A 5wy0A-3ibzA:
undetectable		 5wy0A-3ibzA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_A_TLFA300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 3ibz PUTATIVE TELLURIUM
RESISTANT LIKE
PROTEIN TERD
(Streptomyces
coelicolor) 		5 / 12 PHE A 157
VAL A 109
ILE A  93
VAL A  23
PHE A 169
 None
 1.18A 6ap6A-3ibzA:
undetectable		 6ap6A-3ibzA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_B_TLFB300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 3ibz PUTATIVE TELLURIUM
RESISTANT LIKE
PROTEIN TERD
(Streptomyces
coelicolor) 		5 / 12 PHE A 157
VAL A 109
ILE A  93
VAL A  23
PHE A 169
 None
 1.16A 6ap6B-3ibzA:
undetectable		 6ap6B-3ibzA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_A_H98A501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 3ibz PUTATIVE TELLURIUM
RESISTANT LIKE
PROTEIN TERD
(Streptomyces
coelicolor) 		5 / 12 VAL A 191
VAL A 189
ASP A 113
PHE A  62
ASN A  64
 None
 1.47A 6iblA-3ibzA:
undetectable		 6iblA-3ibzA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_B_H98B501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 3ibz PUTATIVE TELLURIUM
RESISTANT LIKE
PROTEIN TERD
(Streptomyces
coelicolor) 		5 / 12 VAL A 191
VAL A 189
ASP A 113
PHE A  62
ASN A  64
 None
 1.46A 6iblB-3ibzA:
undetectable		 6iblB-3ibzA:
16.75