SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3icq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
5 / 10 LEU T 671
VAL T 719
ILE T 715
LEU T 658
LEU T 654
None
1.19A 1cqpA-3icqT:
undetectable
1cqpB-3icqT:
undetectable
1cqpA-3icqT:
10.79
1cqpB-3icqT:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
5 / 10 LEU T 758
VAL T 757
ILE T 761
GLU T 831
LEU T 780
None
1.19A 1cqpA-3icqT:
undetectable
1cqpB-3icqT:
undetectable
1cqpA-3icqT:
10.79
1cqpB-3icqT:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E3V_B_DXCB801_0
(STEROID
DELTA-ISOMERASE)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
5 / 11 TYR T 537
LEU T 584
MET T 514
ALA T 555
TRP T 556
None
1.43A 1e3vB-3icqT:
undetectable
1e3vB-3icqT:
9.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FFY_A_MRCA1993_1
(ISOLEUCYL-TRNA
SYNTHETASE)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
5 / 12 PRO T 682
GLY T 724
ASN T 728
SER T 626
PHE T 721
None
1.20A 1ffyA-3icqT:
undetectable
1ffyA-3icqT:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OT7_B_IU5B1002_1
(BILE ACID RECEPTOR)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
5 / 12 LEU T 889
MET T 893
ILE T 970
PHE T 966
TYR T 950
None
1.32A 1ot7B-3icqT:
undetectable
1ot7B-3icqT:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_A_SALA710_1
(PROSTAGLANDIN H2
SYNTHASE-1)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
4 / 7 VAL T 509
VAL T 496
LEU T 495
ALA T 461
None
0.87A 1pthA-3icqT:
undetectable
1pthA-3icqT:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_B_SALB711_1
(PROSTAGLANDIN H2
SYNTHASE-1)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
4 / 7 VAL T 509
VAL T 496
LEU T 495
ALA T 461
None
0.86A 1pthB-3icqT:
undetectable
1pthB-3icqT:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_2
(ANDROGEN RECEPTOR)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
4 / 6 ASN T 258
MET T 233
LEU T 273
ILE T 309
None
0.99A 1z95A-3icqT:
undetectable
1z95A-3icqT:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_B_RBFB301_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
5 / 12 ILE T 643
LEU T 642
ALA T 698
GLY T 675
LEU T 615
None
1.19A 2a58A-3icqT:
undetectable
2a58B-3icqT:
undetectable
2a58A-3icqT:
10.37
2a58B-3icqT:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_C_RBFC302_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
5 / 12 ILE T 643
LEU T 642
ALA T 698
GLY T 675
LEU T 615
None
1.19A 2a58B-3icqT:
undetectable
2a58C-3icqT:
undetectable
2a58B-3icqT:
10.37
2a58C-3icqT:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_E_RBFE304_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
5 / 12 ILE T 643
LEU T 642
ALA T 698
GLY T 675
LEU T 615
None
1.19A 2a58D-3icqT:
undetectable
2a58E-3icqT:
undetectable
2a58D-3icqT:
10.37
2a58E-3icqT:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EFJ_A_37TA502_1
(3,7-DIMETHYLXANTHINE
METHYLTRANSFERASE)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
5 / 12 TYR T 147
PHE T 116
ILE T 222
ILE T 188
TYR T 120
None
1.49A 2efjA-3icqT:
undetectable
2efjA-3icqT:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KUH_A_HLTA150_1
(CALMODULIN)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
4 / 6 LEU T 236
MET T 253
LEU T 273
MET T 233
None
1.11A 2kuhA-3icqT:
undetectable
2kuhA-3icqT:
4.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
5 / 12 LEU T 267
LEU T 270
ASN T 271
LEU T 273
LEU T 328
None
1.37A 3d90A-3icqT:
undetectable
3d90A-3icqT:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_C_ROFC903_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
3 / 3 SER T 141
GLN T 140
PHE T 143
None
0.85A 3g4lC-3icqT:
undetectable
3g4lC-3icqT:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDI_A_SAMA601_0
(METHYLTRANSFERASE)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
5 / 12 ILE T 674
PHE T 677
ALA T 718
THR T 722
ILE T 726
None
1.36A 3ndiA-3icqT:
undetectable
3ndiA-3icqT:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PMZ_E_TUBE220_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
4 / 6 TYR T 668
MET T 709
ILE T 715
SER T 605
None
1.30A 3pmzD-3icqT:
undetectable
3pmzD-3icqT:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
4 / 7 VAL T 307
LEU T 328
TYR T 329
LEU T 381
None
1.05A 3qeoB-3icqT:
undetectable
3qeoB-3icqT:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RC0_A_SAMA484_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
5 / 11 VAL T 150
GLY T 155
ALA T 179
LEU T 131
TYR T 120
None
1.26A 3rc0A-3icqT:
undetectable
3rc0A-3icqT:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
5 / 12 ILE T 920
LEU T 886
GLY T 872
GLY T 871
THR T 883
None
0.93A 3vasA-3icqT:
undetectable
3vasA-3icqT:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZS3_A_ACTA1227_0
(THAUMATIN-LIKE
PROTEIN)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
4 / 4 THR T 782
ARG T 786
ASN T 747
ILE T 749
None
1.01A 3zs3A-3icqT:
undetectable
3zs3A-3icqT:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_A_NCTA501_1
(CYTOCHROME P450 2A6)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
4 / 7 PHE T 116
GLY T 155
ILE T 188
PHE T 128
None
0.84A 4ejjA-3icqT:
undetectable
4ejjA-3icqT:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_D_NCTD501_1
(CYTOCHROME P450 2A6)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
4 / 7 PHE T 116
GLY T 155
ILE T 188
PHE T 128
None
0.85A 4ejjD-3icqT:
undetectable
4ejjD-3icqT:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWR_A_ZMRA513_1
(NEURAMINIDASE)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
5 / 12 ARG T 561
GLU T 619
ALA T 683
ARG T 725
ASN T 728
None
None
None
C  D  56 ( 3.0A)
None
1.36A 4mwrA-3icqT:
undetectable
4mwrA-3icqT:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
4 / 7 ASN T 258
MET T 233
LEU T 273
ILE T 309
None
1.02A 4okwA-3icqT:
undetectable
4okwA-3icqT:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA601_1
(SERUM ALBUMIN)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
5 / 12 LEU T 630
PHE T 681
VAL T 621
GLY T 622
LEU T 578
None
1.45A 4ot2A-3icqT:
2.4
4ot2A-3icqT:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
5 / 11 HIS T 504
SER T 454
SER T 441
ALA T 446
THR T 445
None
1.49A 4qvyV-3icqT:
0.0
4qvyb-3icqT:
0.1
4qvyV-3icqT:
12.09
4qvyb-3icqT:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
5 / 11 HIS T 504
SER T 454
SER T 441
ALA T 446
THR T 445
None
1.49A 4qvyH-3icqT:
0.0
4qvyN-3icqT:
0.3
4qvyH-3icqT:
12.09
4qvyN-3icqT:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_B_RTLB201_0
(RETINOL-BINDING
PROTEIN 2)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
5 / 12 PHE T 836
THR T 776
LEU T 819
LEU T 784
LEU T 839
None
1.46A 4qynB-3icqT:
undetectable
4qynB-3icqT:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4USW_A_ACTA1470_0
(ADENYLATE CYCLASE
TYPE 10)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
4 / 6 LEU T 844
LEU T 862
VAL T 863
PHE T 846
None
1.24A 4uswA-3icqT:
undetectable
4uswA-3icqT:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA902_0
(PROTEIN ARGONAUTE-2)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
4 / 6 LEU T 624
ILE T 625
LEU T 578
GLU T 575
None
0.97A 4w5nA-3icqT:
undetectable
4w5nA-3icqT:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_2
(ESTROGEN RECEPTOR)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
4 / 6 ASP T 399
GLU T 406
ILE T 458
HIS T 504
None
0.91A 4xi3C-3icqT:
undetectable
4xi3C-3icqT:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_E_GFNE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
4 / 7 ALA T 438
ASP T 421
GLY T 469
GLU T 470
None
None
None
G  D  51 ( 4.2A)
0.94A 5btdA-3icqT:
undetectable
5btdB-3icqT:
undetectable
5btdC-3icqT:
undetectable
5btdA-3icqT:
19.18
5btdB-3icqT:
13.38
5btdC-3icqT:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
5 / 12 ILE T 715
GLY T 717
GLU T 662
SER T 605
ILE T 606
None
1.02A 5igyA-3icqT:
undetectable
5igyA-3icqT:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
5 / 12 ILE T 715
GLY T 717
GLU T 662
SER T 605
ILE T 606
None
1.02A 5ih0A-3icqT:
undetectable
5ih0A-3icqT:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
3 / 3 SER T 825
LEU T 862
MET T 866
None
0.77A 5ikrB-3icqT:
1.6
5ikrB-3icqT:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
5 / 11 HIS T 504
SER T 454
SER T 441
ALA T 446
THR T 445
None
1.48A 5l5fV-3icqT:
undetectable
5l5fb-3icqT:
undetectable
5l5fV-3icqT:
12.09
5l5fb-3icqT:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
5 / 11 HIS T 504
SER T 454
SER T 441
ALA T 446
THR T 445
None
1.48A 5l5fH-3icqT:
undetectable
5l5fN-3icqT:
undetectable
5l5fH-3icqT:
12.09
5l5fN-3icqT:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_2
(WTFP-TAG,GP41)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
3 / 3 LEU T  62
LEU T  65
TRP T  40
None
0.88A 5nwuA-3icqT:
undetectable
5nwuA-3icqT:
3.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
3 / 3 HIS T 506
GLU T 459
TRP T 397
None
1.06A 5odiD-3icqT:
undetectable
5odiD-3icqT:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
3 / 3 HIS T 506
GLU T 459
TRP T 397
None
1.03A 5odqD-3icqT:
undetectable
5odqD-3icqT:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODR_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
3 / 3 HIS T 506
GLU T 459
TRP T 397
None
1.02A 5odrD-3icqT:
undetectable
5odrD-3icqT:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QSA615_1
(SERUM ALBUMIN)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
4 / 8 LEU T 236
VAL T 228
LEU T 275
ILE T 272
None
0.90A 5v0vA-3icqT:
1.6
5v0vA-3icqT:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_1
(REGULATORY PROTEIN
TETR)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
4 / 8 GLN T 132
TYR T 147
TRP T 218
ASP T 184
None
0.90A 5vlmB-3icqT:
2.1
5vlmB-3icqT:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_1
(REGULATORY PROTEIN
TETR)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
4 / 7 GLN T 132
TYR T 147
TRP T 218
ASP T 184
None
0.95A 5vlmE-3icqT:
2.2
5vlmE-3icqT:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_1
(REGULATORY PROTEIN
TETR)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
4 / 7 GLN T 132
TYR T 147
TRP T 218
ASP T 184
None
1.03A 5vlmG-3icqT:
3.0
5vlmG-3icqT:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW2_A_ACTA511_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
3 / 3 ARG T 362
ILE T 426
SER T 425
U  D  68 ( 3.7A)
None
None
0.78A 5zw2A-3icqT:
undetectable
5zw2A-3icqT:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_1
(SERUM ALBUMIN)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
4 / 5 ASN T 229
VAL T 214
LEU T 151
SER T 190
None
1.29A 6a7pA-3icqT:
2.2
6a7pA-3icqT:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
5 / 10 SER T 340
LEU T 358
LEU T 335
ILE T 423
SER T 380
None
1.48A 6dlzB-3icqT:
2.4
6dlzC-3icqT:
3.1
6dlzB-3icqT:
6.07
6dlzC-3icqT:
6.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
5 / 10 SER T 340
LEU T 358
LEU T 335
ILE T 423
SER T 380
None
1.48A 6dm1B-3icqT:
2.4
6dm1C-3icqT:
3.0
6dm1B-3icqT:
6.07
6dm1C-3icqT:
6.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
5 / 10 SER T 340
LEU T 358
LEU T 335
ILE T 423
SER T 380
None
1.50A 6dm2B-3icqT:
2.2
6dm2C-3icqT:
3.3
6dm2B-3icqT:
6.07
6dm2C-3icqT:
6.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
5 / 10 ILE T 423
SER T 380
SER T 340
LEU T 358
LEU T 335
None
1.49A 6dm2A-3icqT:
2.2
6dm2D-3icqT:
2.2
6dm2A-3icqT:
6.07
6dm2D-3icqT:
6.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3icq EXPORTIN-T
(Schizosaccharomy
ces
pombe)
3 / 3 ARG T  70
LEU T 114
PHE T 116
None
0.77A 6nknP-3icqT:
2.2
6nknP-3icqT:
13.85