SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3icx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 3icx PRE MRNA SPLICING
PROTEIN
(Sulfolobus
solfataricus) 		4 / 5 TYR A 165
TYR A 182
ILE A 176
GLY A 190
 None
 1.34A 1kifA-3icxA:
undetectable		 1kifA-3icxA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 3icx PRE MRNA SPLICING
PROTEIN
(Sulfolobus
solfataricus) 		4 / 5 TYR A 165
TYR A 182
ILE A 176
GLY A 190
 None
 1.34A 1kifB-3icxA:
undetectable		 1kifB-3icxA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 3icx PRE MRNA SPLICING
PROTEIN
(Sulfolobus
solfataricus) 		4 / 5 TYR A 165
TYR A 182
ILE A 176
GLY A 190
 None
 1.34A 1kifC-3icxA:
undetectable		 1kifC-3icxA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 3icx PRE MRNA SPLICING
PROTEIN
(Sulfolobus
solfataricus) 		4 / 5 TYR A 165
TYR A 182
ILE A 176
GLY A 190
 None
 1.34A 1kifD-3icxA:
undetectable		 1kifD-3icxA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 3icx PRE MRNA SPLICING
PROTEIN
(Sulfolobus
solfataricus) 		4 / 5 TYR A 165
TYR A 182
ILE A 176
GLY A 190
 None
 1.34A 1kifE-3icxA:
undetectable		 1kifE-3icxA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 3icx PRE MRNA SPLICING
PROTEIN
(Sulfolobus
solfataricus) 		4 / 5 TYR A 165
TYR A 182
ILE A 176
GLY A 190
 None
 1.34A 1kifF-3icxA:
undetectable		 1kifF-3icxA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 3icx PRE MRNA SPLICING
PROTEIN
(Sulfolobus
solfataricus) 		4 / 5 TYR A 165
TYR A 182
ILE A 176
GLY A 190
 None
 1.34A 1kifG-3icxA:
undetectable		 1kifG-3icxA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 3icx PRE MRNA SPLICING
PROTEIN
(Sulfolobus
solfataricus) 		4 / 5 TYR A 165
TYR A 182
ILE A 176
GLY A 190
 None
 1.34A 1kifH-3icxA:
undetectable		 1kifH-3icxA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 3icx PRE MRNA SPLICING
PROTEIN
(Sulfolobus
solfataricus) 		4 / 5 TYR A 165
TYR A 182
ILE A 176
GLY A 190
 None
 1.36A 1ve9A-3icxA:
undetectable		 1ve9A-3icxA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 3icx PRE MRNA SPLICING
PROTEIN
(Sulfolobus
solfataricus) 		4 / 5 TYR A 165
TYR A 182
ILE A 176
GLY A 190
 None
 1.34A 2du8G-3icxA:
undetectable		 2du8G-3icxA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_A_ADNA1501_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3icx PRE MRNA SPLICING
PROTEIN
(Sulfolobus
solfataricus) 		4 / 7 ARG A 248
GLU A 255
PRO A 271
ALA A 272
 SO4  A 501 (-3.2A)
None
None
None
 1.35A 2ejgA-3icxA:
undetectable		 2ejgA-3icxA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QF1_A_PZEA6951_1
(LACTOPEROXIDASE)		 3icx PRE MRNA SPLICING
PROTEIN
(Sulfolobus
solfataricus) 		3 / 3 HIS A 179
ARG A 162
GLU A 159
 None
 1.16A 3qf1A-3icxA:
undetectable		 3qf1A-3icxA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_B_SALB404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 3icx PRE MRNA SPLICING
PROTEIN
(Sulfolobus
solfataricus) 		4 / 7 ALA A 340
TYR A 323
ARG A 334
ALA A 325
 None
 0.90A 3twpB-3icxA:
undetectable		 3twpB-3icxA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_C_SALC404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 3icx PRE MRNA SPLICING
PROTEIN
(Sulfolobus
solfataricus) 		4 / 7 ALA A 340
TYR A 323
ARG A 334
ALA A 325
 None
 0.96A 3twpC-3icxA:
undetectable		 3twpC-3icxA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7G_A_ACTA514_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3icx PRE MRNA SPLICING
PROTEIN
(Sulfolobus
solfataricus) 		4 / 4 ALA A 348
VAL A 265
ASP A 352
LEU A 278
 None
 1.46A 4e7gA-3icxA:
undetectable		 4e7gA-3icxA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_B_MN9B401_0
(N-ACETYLNEURAMINATE
LYASE)		 3icx PRE MRNA SPLICING
PROTEIN
(Sulfolobus
solfataricus) 		4 / 6 SER A 283
LEU A 284
ASP A 285
LEU A 278
 None
 0.96A 4wozA-3icxA:
undetectable
4wozB-3icxA:
undetectable		 4wozA-3icxA:
23.36
4wozB-3icxA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Z_BEZZ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 3icx PRE MRNA SPLICING
PROTEIN
(Sulfolobus
solfataricus) 		4 / 4 ILE A 280
GLY A 274
ILE A 319
LEU A 278
 None
 0.89A 5dzkl-3icxA:
undetectable
5dzkz-3icxA:
undetectable		 5dzkl-3icxA:
22.90
5dzkz-3icxA:
1.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_C_REAC602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 3icx PRE MRNA SPLICING
PROTEIN
(Sulfolobus
solfataricus) 		5 / 10 GLY A 270
GLN A 362
PHE A 358
ASN A 264
LEU A 278
 None
 1.20A 5fhzC-3icxA:
undetectable		 5fhzC-3icxA:
19.74