SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3id3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NBQ_B_URFB400_1 (URIDINE PHOSPHORYLASE 1)	3id3	REGULATOR OF SIGMA E PROTEASE (Escherichia coli)	4 / 8	GLY A 239 ARG A 278 LEU A 285 ILE A 276	None	0.83A	3nbqB-3id3A: undetectable	3nbqB-3id3A: 14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NBQ_C_URFC400_1 (URIDINE PHOSPHORYLASE 1)	3id3	REGULATOR OF SIGMA E PROTEASE (Escherichia coli)	4 / 8	GLY A 239 ARG A 278 LEU A 285 ILE A 276	None	0.83A	3nbqC-3id3A: undetectable	3nbqC-3id3A: 14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M93_B_ACTB303_0 (S25-26 FAB (IGG1K) HEAVY CHAIN S25-26 FAB (IGG1K) LIGHT CHAIN)	3id3	REGULATOR OF SIGMA E PROTEASE (Escherichia coli)	5 / 5	GLY A 303 SER A 233 ALA A 234 PHE A 301 GLU A 290	None	1.33A	4m93B-3id3A: undetectable 4m93C-3id3A: undetectable	4m93B-3id3A: 18.06 4m93C-3id3A: 17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XDR_A_ADNA402_1 (FAD:PROTEIN FMN TRANSFERASE)	3id3	REGULATOR OF SIGMA E PROTEASE (Escherichia coli)	5 / 12	LEU A 226 VAL A 229 GLY A 239 ALA A 238 VAL A 264	None	1.02A	4xdrA-3id3A: undetectable	4xdrA-3id3A: 15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5T2Z_B_017B201_1 (PROTEASE)	3id3	REGULATOR OF SIGMA E PROTEASE (Escherichia coli)	5 / 12	ASP A 244 GLY A 243 VAL A 247 GLY A 280 ILE A 276	None	1.04A	5t2zA-3id3A: undetectable	5t2zA-3id3A: 22.77

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3NBQ_B_URFB400_1","URIDINE PHOSPHORYLASE 1","3id3","REGULATOR OF SIGMA E PROTEASE","Escherichia coli",4,"GLY A 239;ARG A 278;LEU A 285;ILE A 276","None","0.83A","3nbqB-3id3A:undetectable","3nbqB-3id3A:14.11"],["3NBQ_C_URFC400_1","URIDINE PHOSPHORYLASE 1","3id3","REGULATOR OF SIGMA E PROTEASE","Escherichia coli",4,"GLY A 239;ARG A 278;LEU A 285;ILE A 276","None","0.83A","3nbqC-3id3A:undetectable","3nbqC-3id3A:14.11"],["4M93_B_ACTB303_0","S25-26 FAB (IGG1K) HEAVY CHAIN;S25-26 FAB (IGG1K) LIGHT CHAIN","3id3","REGULATOR OF SIGMA E PROTEASE","Escherichia coli",5,"GLY A 303;SER A 233;ALA A 234;PHE A 301;GLU A 290","None","1.33A","4m93B-3id3A:undetectable;4m93C-3id3A:undetectable","4m93B-3id3A:18.06;4m93C-3id3A:17.67"],["4XDR_A_ADNA402_1","FAD:PROTEIN FMN TRANSFERASE","3id3","REGULATOR OF SIGMA E PROTEASE","Escherichia coli",5,"LEU A 226;VAL A 229;GLY A 239;ALA A 238;VAL A 264","None","1.02A","4xdrA-3id3A:undetectable","4xdrA-3id3A:15.15"],["5T2Z_B_017B201_1","PROTEASE;PROTEASE","3id3","REGULATOR OF SIGMA E PROTEASE","Escherichia coli",5,"ASP A 244;GLY A 243;VAL A 247;GLY A 280;ILE A 276","None","1.04A","5t2zA-3id3A:undetectable","5t2zA-3id3A:22.77"]]