SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3idu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SN0_B_T44B602_1 (TRANSTHYRETIN)	3idu	UNCHARACTERIZED PROTEIN (Pyrococcus furiosus)	4 / 7	LYS A 463 LEU A 465 GLU A 496 LYS A 427	None	0.98A	1sn0B-3iduA: undetectable 1sn0D-3iduA: 4.0	1sn0B-3iduA: 24.65 1sn0D-3iduA: 24.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SN5_C_T3C601_1 (TRANSTHYRETIN)	3idu	UNCHARACTERIZED PROTEIN (Pyrococcus furiosus)	4 / 6	LYS A 463 LEU A 465 GLU A 496 VAL A 517	None	1.16A	1sn5A-3iduA: 4.0	1sn5A-3iduA: 24.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_G_TRPG1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	3idu	UNCHARACTERIZED PROTEIN (Pyrococcus furiosus)	4 / 8	GLY A 446 ILE A 513 VAL A 537 VAL A 450	None	0.69A	3fi0G-3iduA: undetectable	3fi0G-3iduA: 17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_I_TRPI1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	3idu	UNCHARACTERIZED PROTEIN (Pyrococcus furiosus)	4 / 8	GLY A 446 ILE A 513 VAL A 537 VAL A 450	None	0.77A	3fi0I-3iduA: undetectable	3fi0I-3iduA: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1SN0_B_T44B602_1","TRANSTHYRETIN;TRANSTHYRETIN","3idu","UNCHARACTERIZED PROTEIN","Pyrococcus furiosus",4,"LYS A 463;LEU A 465;GLU A 496;LYS A 427","None","0.98A","1sn0B-3iduA:undetectable;1sn0D-3iduA:4.0","1sn0B-3iduA:24.65;1sn0D-3iduA:24.65"],["1SN5_C_T3C601_1","TRANSTHYRETIN;TRANSTHYRETIN","3idu","UNCHARACTERIZED PROTEIN","Pyrococcus furiosus",4,"LYS A 463;LEU A 465;GLU A 496;VAL A 517","None","1.16A","1sn5A-3iduA:4.0","1sn5A-3iduA:24.65"],["3FI0_G_TRPG1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","3idu","UNCHARACTERIZED PROTEIN","Pyrococcus furiosus",4,"GLY A 446;ILE A 513;VAL A 537;VAL A 450","None","0.69A","3fi0G-3iduA:undetectable","3fi0G-3iduA:17.79"],["3FI0_I_TRPI1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","3idu","UNCHARACTERIZED PROTEIN","Pyrococcus furiosus",4,"GLY A 446;ILE A 513;VAL A 537;VAL A 450","None","0.77A","3fi0I-3iduA:undetectable","3fi0I-3iduA:undetectable"]]