SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3idv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZW9_A_SAMA801_1 (LEUCINE CARBOXYL METHYLTRANSFERASE 2)	3idv	PROTEIN DISULFIDE-ISOMERASE A4 (Homo sapiens)	4 / 8	THR A 81 LEU A 108 ASP A 112 GLU A 166	None	1.03A	2zw9A-3idvA: undetectable	2zw9A-3idvA: 16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P73_A_ACTA275_0 (MHC RFP-Y CLASS I ALPHA CHAIN)	3idv	PROTEIN DISULFIDE-ISOMERASE A4 (Homo sapiens)	3 / 3	ILE A 107 VAL A 161 ARG A 165	None	0.45A	3p73A-3idvA: undetectable	3p73A-3idvA: 21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SMT_A_ACTA1001_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SETD3)	3idv	PROTEIN DISULFIDE-ISOMERASE A4 (Homo sapiens)	4 / 5	GLY A 261 PHE A 258 PHE A 247 ARG A 246	None	1.18A	3smtA-3idvA: undetectable	3smtA-3idvA: 19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5W7B_B_PA1B204_1 (ACYLOXYACYL HYDROLASE SMALL SUBUNIT ACYLOXYACYL HYDROLASE LARGE SUBUNIT)	3idv	PROTEIN DISULFIDE-ISOMERASE A4 (Homo sapiens)	3 / 3	GLY A 261 ASN A 192 ARG A 246	None	0.76A	5w7bD-3idvA: undetectable	5w7bD-3idvA: 17.03

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2ZW9_A_SAMA801_1","LEUCINE CARBOXYL METHYLTRANSFERASE 2","3idv","PROTEIN DISULFIDE-ISOMERASE A4","Homo sapiens",4,"THR A  81;LEU A 108;ASP A 112;GLU A 166","None","1.03A","2zw9A-3idvA:undetectable","2zw9A-3idvA:16.29"],["3P73_A_ACTA275_0","MHC RFP-Y CLASS I ALPHA CHAIN","3idv","PROTEIN DISULFIDE-ISOMERASE A4","Homo sapiens",3,"ILE A 107;VAL A 161;ARG A 165","None","0.45A","3p73A-3idvA:undetectable","3p73A-3idvA:21.32"],["3SMT_A_ACTA1001_0","HISTONE-LYSINE N-METHYLTRANSFERASE SETD3","3idv","PROTEIN DISULFIDE-ISOMERASE A4","Homo sapiens",4,"GLY A 261;PHE A 258;PHE A 247;ARG A 246","None","1.18A","3smtA-3idvA:undetectable","3smtA-3idvA:19.56"],["5W7B_B_PA1B204_1","ACYLOXYACYL HYDROLASE SMALL SUBUNIT;ACYLOXYACYL HYDROLASE LARGE SUBUNIT","3idv","PROTEIN DISULFIDE-ISOMERASE A4","Homo sapiens",3,"GLY A 261;ASN A 192;ARG A 246","None","0.76A","5w7bD-3idvA:undetectable","5w7bD-3idvA:17.03"]]