SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3iee'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3iee PUTATIVE EXPORTED
PROTEIN
(Bacteroides
fragilis) 		4 / 5 LEU A 145
VAL A 148
LEU A 152
GLN A 155
 None
 0.59A 1fbmE-3ieeA:
undetectable		 1fbmE-3ieeA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_1
(DIPEPTIDYL PEPTIDASE
4)		 3iee PUTATIVE EXPORTED
PROTEIN
(Bacteroides
fragilis) 		5 / 12 ARG A 264
SER A 153
VAL A  57
ASN A  63
VAL A  62
 None
EDO  A 302 (-2.8A)
None
EDO  A 302 (-3.5A)
EDO  A 302 (-4.3A)
 1.37A 4ffwA-3ieeA:
undetectable		 4ffwA-3ieeA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_F_BEZF201_0
(NS3 PROTEASE)		 3iee PUTATIVE EXPORTED
PROTEIN
(Bacteroides
fragilis) 		4 / 5 ALA A 272
SER A 270
TYR A 269
TYR A 205
 None
 1.26A 5yodF-3ieeA:
undetectable		 5yodF-3ieeA:
20.15