SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ief'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UAK_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3ief TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Bartonella
henselae) 		8 / 12 SER A  86
PRO A  87
GLY A 111
SER A 130
ILE A 131
LEU A 136
GLY A 138
GLY A 139
 None
 0.63A 1uakA-3iefA:
21.1		 1uakA-3iefA:
42.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AXZ_A_ADNA401_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3ief TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Bartonella
henselae) 		6 / 12 GLY A 111
SER A 130
ILE A 131
LEU A 136
GLY A 138
GLY A 139
 None
 0.59A 3axzA-3iefA:
21.9		 3axzA-3iefA:
43.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AXZ_A_ADNA401_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3ief TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Bartonella
henselae) 		7 / 12 SER A  86
PRO A  87
SER A 130
ILE A 131
LEU A 136
GLY A 138
GLY A 139
 None
 0.43A 3axzA-3iefA:
21.9		 3axzA-3iefA:
43.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_B_SAMB300_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 3ief TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Bartonella
henselae) 		5 / 12 PHE A  15
LEU A 144
GLY A  20
GLY A  17
ALA A  24
 None
 1.10A 3dh0B-3iefA:
undetectable		 3dh0B-3iefA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_B_TOPB200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 3ief TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Bartonella
henselae) 		5 / 12 ALA A 142
LEU A  92
VAL A 129
ILE A 150
LEU A 100
 None
 1.10A 3fl9B-3iefA:
undetectable		 3fl9B-3iefA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_C_TOPC200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 3ief TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Bartonella
henselae) 		5 / 11 ALA A 142
LEU A  92
VAL A 129
ILE A 150
LEU A 100
 None
 1.12A 3fl9C-3iefA:
undetectable		 3fl9C-3iefA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_H_TOPH200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 3ief TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Bartonella
henselae) 		5 / 9 ALA A 142
LEU A  92
VAL A 129
ILE A 150
LEU A 100
 None
 1.18A 3fl9H-3iefA:
undetectable		 3fl9H-3iefA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_1
(METHYLTRANSFERASE
MPPJ)		 3ief TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Bartonella
henselae) 		3 / 3 ARG A 124
ASP A 117
ASP A  53
 None
 0.88A 4kicB-3iefA:
undetectable		 4kicB-3iefA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_B_ACTB401_0
(UNCHARACTERIZED
PROTEIN)		 3ief TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Bartonella
henselae) 		4 / 5 GLU A 127
VAL A 129
LEU A 100
VAL A 106
 None
 1.01A 4lb0B-3iefA:
undetectable		 4lb0B-3iefA:
23.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YVG_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3ief TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Bartonella
henselae) 		8 / 12 SER A  86
PRO A  87
GLY A 111
SER A 130
ILE A 131
LEU A 136
GLY A 138
GLY A 139
 None
 0.59A 4yvgA-3iefA:
21.4		 4yvgA-3iefA:
43.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_A_SAMA801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 3ief TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Bartonella
henselae) 		5 / 12 ASP A  79
ALA A   5
LEU A  35
GLU A  36
VAL A   7
 None
 1.22A 5hw4A-3iefA:
2.8		 5hw4A-3iefA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_B_SAMB801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 3ief TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Bartonella
henselae) 		5 / 11 ASP A  79
ALA A   5
LEU A  35
GLU A  36
VAL A   7
 None
 1.16A 5hw4B-3iefA:
undetectable		 5hw4B-3iefA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_C_SAMC801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 3ief TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Bartonella
henselae) 		5 / 12 ASP A  79
ALA A   5
LEU A  35
GLU A  36
VAL A   7
 None
 1.20A 5hw4C-3iefA:
2.5		 5hw4C-3iefA:
23.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WYQ_A_SAMA401_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3ief TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Bartonella
henselae) 		7 / 12 PRO A  87
GLY A 111
SER A 130
ILE A 131
LEU A 136
GLY A 138
GLY A 139
 None
 0.58A 5wyqA-3iefA:
21.5		 5wyqA-3iefA:
42.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WYQ_B_SAMB301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3ief TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Bartonella
henselae) 		6 / 12 PRO A  87
GLY A 111
ILE A 131
TYR A 134
LEU A 136
GLY A 139
 None
 1.14A 5wyqB-3iefA:
21.8		 5wyqB-3iefA:
42.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WYQ_B_SAMB301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3ief TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Bartonella
henselae) 		8 / 12 PRO A  87
GLY A 111
SER A 130
ILE A 131
TYR A 134
LEU A 136
GLY A 138
GLY A 139
 None
 0.59A 5wyqB-3iefA:
21.8		 5wyqB-3iefA:
42.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZHM_B_SAMB301_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3ief TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Bartonella
henselae) 		6 / 12 PRO A  87
GLY A 111
GLY A 115
SER A 130
ILE A 131
LEU A 136
 None
 0.74A 5zhmB-3iefA:
22.3		 5zhmB-3iefA:
41.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZHM_B_SAMB301_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3ief TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Bartonella
henselae) 		7 / 12 PRO A  87
GLY A 111
SER A 130
ILE A 131
LEU A 136
GLY A 138
GLY A 139
 None
 0.48A 5zhmB-3iefA:
22.3		 5zhmB-3iefA:
41.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3ief TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Bartonella
henselae) 		5 / 12 VAL A   7
THR A   9
LEU A 100
LEU A  92
VAL A 129
 None
 1.24A 6a93B-3iefA:
undetectable		 6a93B-3iefA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_B_P2EB1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 3ief TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Bartonella
henselae) 		4 / 5 PRO A  81
VAL A 106
GLY A 111
VAL A 129
 None
 1.08A 6ak3B-3iefA:
undetectable		 6ak3B-3iefA:
16.74