SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3if1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_D_DMED999_1
(ACETYLCHOLINESTERASE)		 3if1 IMMUNOGLOBULIN HEAVY
CHAIN (IGG2A)
(Mus
musculus) 		4 / 8 GLY B  88
TYR B  90
GLU B  42
SER B  40
 None
 1.02A 1maaD-3if1B:
undetectable		 1maaD-3if1B:
16.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXT_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-3 GRAFT VHH)		 3if1 IMMUNOGLOBULIN HEAVY
CHAIN (IGG2A)
(Mus
musculus) 		6 / 12 VAL B   2
LEU B   4
ALA B  24
MET B  34
ARG B  71
TYR B 102
 None
 0.67A 3qxtB-3if1B:
20.1		 3qxtB-3if1B:
32.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 3if1 IMMUNOGLOBULIN HEAVY
CHAIN (IGG2A)
(Mus
musculus) 		5 / 12 VAL B   2
ALA B  24
MET B  34
ARG B  71
TYR B 102
 None
 0.74A 3qxvB-3if1B:
19.6		 3qxvB-3if1B:
32.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_D_MTXD2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 3if1 IMMUNOGLOBULIN HEAVY
CHAIN (IGG2A)
(Mus
musculus) 		5 / 12 VAL B   2
ALA B  24
MET B  34
ARG B  71
TYR B 102
 None
 0.70A 3qxvD-3if1B:
19.5		 3qxvD-3if1B:
32.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 3if1 IMMUNOGLOBULIN HEAVY
CHAIN (IGG2A)
(Mus
musculus) 		3 / 3 SER B 203
ALA B 198
VAL B 197
 None
 0.69A 4o2bC-3if1B:
undetectable		 4o2bC-3if1B:
18.96