SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3if2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_D_RITD401_2
(PROTEASE)		 3if2 AMINOTRANSFERASE
(Psychrobacter
arcticus) 		4 / 6 GLY A  37
ILE A 392
PRO A 217
ILE A 155
 None
 0.73A 1n49D-3if2A:
undetectable		 1n49D-3if2A:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_B_P1ZB2001_1
(SERUM ALBUMIN)		 3if2 AMINOTRANSFERASE
(Psychrobacter
arcticus) 		5 / 9 LEU A  91
LEU A 110
ARG A 309
ALA A 313
ALA A  86
 None
 1.28A 2bxcB-3if2A:
undetectable		 2bxcB-3if2A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_D_SALD5006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3if2 AMINOTRANSFERASE
(Psychrobacter
arcticus) 		4 / 5 PHE A  87
THR A 283
LEU A 278
ALA A 313
 None
 1.36A 2e1qD-3if2A:
undetectable		 2e1qD-3if2A:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_C_ADNC903_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 3if2 AMINOTRANSFERASE
(Psychrobacter
arcticus) 		5 / 12 ILE A 285
THR A 308
VAL A 319
PHE A  87
SER A  74
 None
 1.42A 2gl0A-3if2A:
undetectable
2gl0C-3if2A:
undetectable		 2gl0A-3if2A:
16.37
2gl0C-3if2A:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_D_ADND904_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 3if2 AMINOTRANSFERASE
(Psychrobacter
arcticus) 		5 / 12 PHE A  87
SER A  74
ILE A 285
THR A 308
VAL A 319
 None
 1.40A 2gl0D-3if2A:
undetectable
2gl0E-3if2A:
undetectable		 2gl0D-3if2A:
16.37
2gl0E-3if2A:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3if2 AMINOTRANSFERASE
(Psychrobacter
arcticus) 		5 / 12 LEU A  23
LEU A 391
MET A  35
ILE A 155
VAL A 431
 None
 1.33A 2pnjB-3if2A:
undetectable		 2pnjB-3if2A:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO5_A_CHDA131_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 3if2 AMINOTRANSFERASE
(Psychrobacter
arcticus) 		5 / 12 ILE A 255
ILE A 285
ILE A 276
VAL A 319
LEU A 261
 None
 1.15A 2qo5A-3if2A:
undetectable		 2qo5A-3if2A:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3if2 AMINOTRANSFERASE
(Psychrobacter
arcticus) 		5 / 12 SER A 395
TYR A 188
LEU A 356
HIS A 409
TYR A 407
 None
 1.38A 3adxA-3if2A:
undetectable		 3adxA-3if2A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_A_THHA401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 3if2 AMINOTRANSFERASE
(Psychrobacter
arcticus) 		6 / 12 ILE A  16
LEU A  19
LEU A  23
THR A 151
VAL A 393
PRO A 400
 None
 1.42A 3dcjA-3if2A:
undetectable
3dcjB-3if2A:
undetectable		 3dcjA-3if2A:
17.98
3dcjB-3if2A:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTR_A_LQZA90_1
(LACTOTRANSFERRIN)		 3if2 AMINOTRANSFERASE
(Psychrobacter
arcticus) 		3 / 3 PRO A 214
THR A 215
LEU A 222
 None
 0.51A 3ttrA-3if2A:
undetectable		 3ttrA-3if2A:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_A_ADNA901_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3if2 AMINOTRANSFERASE
(Psychrobacter
arcticus) 		5 / 9 ALA A 350
ARG A 437
GLY A 352
LEU A 347
ILE A 358
 None
 1.37A 3wdmA-3if2A:
2.0		 3wdmA-3if2A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3if2 AMINOTRANSFERASE
(Psychrobacter
arcticus) 		4 / 8 SER A 158
ARG A 415
ILE A  16
PHE A 398
 None
 1.21A 4cx7A-3if2A:
undetectable
4cx7B-3if2A:
undetectable		 4cx7A-3if2A:
21.29
4cx7B-3if2A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_C_H4BC600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3if2 AMINOTRANSFERASE
(Psychrobacter
arcticus) 		4 / 8 SER A 158
ARG A 415
ILE A  16
PHE A 398
 None
 1.15A 4cx7C-3if2A:
undetectable
4cx7D-3if2A:
undetectable		 4cx7C-3if2A:
21.29
4cx7D-3if2A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESF_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3if2 AMINOTRANSFERASE
(Psychrobacter
arcticus) 		4 / 8 ILE A 155
TYR A 154
PHE A 366
GLY A  38
 None
PLP  A 500 (-3.8A)
None
None
 0.89A 5esfA-3if2A:
undetectable		 5esfA-3if2A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 3if2 AMINOTRANSFERASE
(Psychrobacter
arcticus) 		4 / 8 LEU A 351
LEU A 439
THR A 378
TRP A 368
 None
 1.09A 5hbsA-3if2A:
undetectable		 5hbsA-3if2A:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IM2_A_BEZA401_0
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL)		 3if2 AMINOTRANSFERASE
(Psychrobacter
arcticus) 		5 / 12 VAL A 190
ILE A 233
LEU A 147
LEU A 198
VAL A 170
 None
 1.27A 5im2A-3if2A:
undetectable		 5im2A-3if2A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JO9_A_SORA302_0
(RIBITOL
2-DEHYDROGENASE)		 3if2 AMINOTRANSFERASE
(Psychrobacter
arcticus) 		5 / 12 TYR A 157
LEU A 150
THR A 215
PRO A 149
LEU A 222
 None
 1.21A 5jo9A-3if2A:
undetectable		 5jo9A-3if2A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_1
(PROTEIN CYP51)		 3if2 AMINOTRANSFERASE
(Psychrobacter
arcticus) 		5 / 12 ALA A 290
PHE A 251
ALA A 315
LEU A 110
THR A 104
 None
 1.25A 5tl8A-3if2A:
undetectable		 5tl8A-3if2A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3if2 AMINOTRANSFERASE
(Psychrobacter
arcticus) 		4 / 8 THR A 151
THR A 218
ARG A 415
TRP A 368
 None
 1.32A 5tzoA-3if2A:
undetectable		 5tzoA-3if2A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3if2 AMINOTRANSFERASE
(Psychrobacter
arcticus) 		4 / 8 THR A 151
THR A 218
ARG A 415
TRP A 368
 None
 1.20A 5tzoB-3if2A:
undetectable		 5tzoB-3if2A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3if2 AMINOTRANSFERASE
(Psychrobacter
arcticus) 		4 / 8 THR A 151
THR A 218
ARG A 415
TRP A 368
 None
 1.28A 5tzoC-3if2A:
undetectable		 5tzoC-3if2A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_1
(CYTOCHROME P450 3A4)		 3if2 AMINOTRANSFERASE
(Psychrobacter
arcticus) 		5 / 12 SER A 328
LEU A 278
PHE A 118
ILE A 365
ALA A 364
 None
None
PLP  A 500 (-4.9A)
None
None
 1.13A 5vc0A-3if2A:
undetectable		 5vc0A-3if2A:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 3if2 AMINOTRANSFERASE
(Psychrobacter
arcticus) 		4 / 5 ALA A 340
TYR A 256
GLN A 339
ILE A 365
 None
 1.37A 6f6sA-3if2A:
undetectable
6f6sB-3if2A:
undetectable		 6f6sA-3if2A:
9.71
6f6sB-3if2A:
12.22