SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3if9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_0
(FTSJ)		 3if9 GLYCINE OXIDASE
(Bacillus
subtilis) 		5 / 12 ALA A  18
GLY A 331
GLY A  13
GLY A  16
ARG A  54
 None
FAD  A 371 (-3.1A)
FAD  A 371 (-3.2A)
None
None
 0.99A 1eizA-3if9A:
undetectable		 1eizA-3if9A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_0
(FTSJ)		 3if9 GLYCINE OXIDASE
(Bacillus
subtilis) 		5 / 12 ALA A  18
GLY A 331
GLY A  13
GLY A  16
ARG A  54
 None
FAD  A 371 (-3.1A)
FAD  A 371 (-3.2A)
None
None
 0.99A 1ej0A-3if9A:
undetectable		 1ej0A-3if9A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3if9 GLYCINE OXIDASE
(Bacillus
subtilis) 		5 / 12 ALA A 160
ALA A 161
LEU A  80
ILE A  15
LEU A  32
 None
None
None
FAD  A 371 (-4.1A)
None
 1.01A 1fm6U-3if9A:
undetectable		 1fm6U-3if9A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_A_DVAA6_0
(MINI-GRAMICIDIN A)		 3if9 GLYCINE OXIDASE
(Bacillus
subtilis) 		3 / 3 ALA A 325
VAL A 204
TRP A 205
 None
 0.87A 1kqeA-3if9A:
undetectable
1kqeE-3if9A:
undetectable		 1kqeA-3if9A:
2.56
1kqeE-3if9A:
2.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_B_DVAB6_0
(MINI-GRAMICIDIN A)		 3if9 GLYCINE OXIDASE
(Bacillus
subtilis) 		3 / 3 ALA A 325
VAL A 204
TRP A 205
 None
 0.87A 1kqeB-3if9A:
undetectable
1kqeD-3if9A:
undetectable		 1kqeB-3if9A:
2.56
1kqeD-3if9A:
2.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_D_DVAD6_0
(MINI-GRAMICIDIN A)		 3if9 GLYCINE OXIDASE
(Bacillus
subtilis) 		3 / 3 TRP A 205
ALA A 325
VAL A 204
 None
 0.85A 1kqeB-3if9A:
undetectable
1kqeD-3if9A:
undetectable		 1kqeB-3if9A:
2.56
1kqeD-3if9A:
2.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_E_DVAE6_0
(MINI-GRAMICIDIN A)		 3if9 GLYCINE OXIDASE
(Bacillus
subtilis) 		3 / 3 TRP A 205
ALA A 325
VAL A 204
 None
 0.88A 1kqeA-3if9A:
undetectable
1kqeE-3if9A:
undetectable		 1kqeA-3if9A:
2.56
1kqeE-3if9A:
2.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T46_A_STIA3_2
(HOMO SAPIENS V-KIT
HARDY-ZUCKERMAN 4
FELINE SARCOMA VIRAL
ONCOGENE HOMOLOG)		 3if9 GLYCINE OXIDASE
(Bacillus
subtilis) 		4 / 7 VAL A 294
TYR A 241
CYH A 245
CYH A 226
 None
None
None
FAD  A 371 (-3.1A)
 1.30A 1t46A-3if9A:
undetectable		 1t46A-3if9A:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1301_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 3if9 GLYCINE OXIDASE
(Bacillus
subtilis) 		4 / 6 LEU A 322
PHE A 323
ALA A 324
LEU A 345
 None
 0.88A 1ukbA-3if9A:
undetectable		 1ukbA-3if9A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IJ7_C_TPFC2471_1
(CYTOCHROME P450 121)		 3if9 GLYCINE OXIDASE
(Bacillus
subtilis) 		4 / 8 THR A 239
VAL A 248
VAL A 257
ARG A 329
 None
None
None
GOA  A 370 ( 3.1A)
 1.17A 2ij7C-3if9A:
undetectable		 2ij7C-3if9A:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_B_REAB1445_1
(PUTATIVE CYTOCHROME
P450 120)		 3if9 GLYCINE OXIDASE
(Bacillus
subtilis) 		5 / 12 PHE A 210
ALA A  18
ALA A 337
GLY A 313
PRO A 310
 None
 1.16A 2ve3B-3if9A:
undetectable		 2ve3B-3if9A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_A_ADNA601_1
(METHIONYL-TRNA
SYNTHETASE)		 3if9 GLYCINE OXIDASE
(Bacillus
subtilis) 		5 / 11 ALA A 201
ALA A 324
GLY A 331
HIS A 327
GLY A  13
 None
None
FAD  A 371 (-3.1A)
None
FAD  A 371 (-3.2A)
 1.16A 2x1lA-3if9A:
undetectable		 2x1lA-3if9A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_B_CTCB1385_0
(TETX2 PROTEIN)		 3if9 GLYCINE OXIDASE
(Bacillus
subtilis) 		4 / 8 PHE A 219
GLY A 203
PRO A 310
GLY A 308
 None
FAD  A 371 (-3.5A)
None
None
 0.94A 2y6rB-3if9A:
15.0		 2y6rB-3if9A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_C_SALC1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3if9 GLYCINE OXIDASE
(Bacillus
subtilis) 		5 / 12 ILE A 312
GLY A 313
PHE A 210
HIS A 327
PRO A 310
 None
 1.34A 2y7kC-3if9A:
undetectable		 2y7kC-3if9A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF0_A_PAUA314_0
(PANTOTHENATE KINASE)		 3if9 GLYCINE OXIDASE
(Bacillus
subtilis) 		4 / 8 ASP A 104
LEU A 108
HIS A 242
TYR A 241
 None
 1.00A 3af0A-3if9A:
undetectable		 3af0A-3if9A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 3if9 GLYCINE OXIDASE
(Bacillus
subtilis) 		3 / 3 ARG A 254
ASP A 232
ASP A 295
 None
 0.89A 3jb2A-3if9A:
2.1		 3jb2A-3if9A:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 3if9 GLYCINE OXIDASE
(Bacillus
subtilis) 		3 / 3 ARG A 254
ASP A 232
ASP A 295
 None
 0.84A 3jb3A-3if9A:
undetectable		 3jb3A-3if9A:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK201_1
(PROTEIN S100-A4)		 3if9 GLYCINE OXIDASE
(Bacillus
subtilis) 		4 / 8 GLY A 308
ILE A 361
PHE A 209
PHE A 219
 None
None
FAD  A 371 (-4.7A)
None
 0.93A 3ko0K-3if9A:
undetectable
3ko0S-3if9A:
undetectable		 3ko0K-3if9A:
13.23
3ko0S-3if9A:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3if9 GLYCINE OXIDASE
(Bacillus
subtilis) 		5 / 12 LEU A 220
GLU A 225
GLY A 264
LEU A 301
ALA A 259
 None
None
None
None
GOA  A 370 ( 4.0A)
 1.20A 3ou6C-3if9A:
2.9		 3ou6C-3if9A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_B_DM2B1104_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3if9 GLYCINE OXIDASE
(Bacillus
subtilis) 		4 / 8 GLN A 212
PHE A 209
ILE A 321
VAL A 198
 None
FAD  A 371 (-4.7A)
None
None
 0.92A 4dx7B-3if9A:
undetectable		 4dx7B-3if9A:
16.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YSH_B_GLYB402_0
(GLYCINE OXIDASE)		 3if9 GLYCINE OXIDASE
(Bacillus
subtilis) 		4 / 5 MET A  49
TYR A 246
ARG A 302
ARG A 329
 FAD  A 371 (-4.4A)
GOA  A 370 ( 4.5A)
GOA  A 370 ( 4.0A)
GOA  A 370 ( 3.1A)
 0.51A 4yshB-3if9A:
52.7		 4yshB-3if9A:
38.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_H_TR6H101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 3if9 GLYCINE OXIDASE
(Bacillus
subtilis) 		3 / 5 GLY A  40
GLY A  36
GLU A 170
 None
 0.38A 4z2eA-3if9A:
undetectable
4z2eD-3if9A:
undetectable		 4z2eA-3if9A:
22.85
4z2eD-3if9A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_A_BEZA507_0
(BETA-LACTAMASE VIM-2)		 3if9 GLYCINE OXIDASE
(Bacillus
subtilis) 		3 / 3 THR A 237
HIS A  91
ASN A  92
 None
 0.86A 5n4tA-3if9A:
undetectable		 5n4tA-3if9A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3if9 GLYCINE OXIDASE
(Bacillus
subtilis) 		3 / 3 TYR A 157
ALA A 340
TYR A  22
 None
 0.75A 5uunB-3if9A:
undetectable		 5uunB-3if9A:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6J_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3if9 GLYCINE OXIDASE
(Bacillus
subtilis) 		3 / 3 MET A 111
ASP A 145
ARG A 329
 None
None
GOA  A 370 ( 3.1A)
 0.93A 5z6jA-3if9A:
undetectable		 5z6jA-3if9A:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6K_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3if9 GLYCINE OXIDASE
(Bacillus
subtilis) 		3 / 3 MET A 111
ASP A 145
ARG A 329
 None
None
GOA  A 370 ( 3.1A)
 1.16A 5z6kA-3if9A:
undetectable		 5z6kA-3if9A:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		 3if9 GLYCINE OXIDASE
(Bacillus
subtilis) 		5 / 12 LEU A 213
VAL A 200
LEU A 345
THR A 338
LEU A 341
 None
 1.13A 6b54A-3if9A:
undetectable		 6b54A-3if9A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		 3if9 GLYCINE OXIDASE
(Bacillus
subtilis) 		5 / 9 VAL A 200
ALA A 201
SER A 202
VAL A 198
GLY A  16
 None
None
FAD  A 371 (-3.5A)
None
None
 1.20A 6bklA-3if9A:
undetectable
6bklB-3if9A:
undetectable
6bklC-3if9A:
undetectable
6bklD-3if9A:
undetectable		 6bklA-3if9A:
4.86
6bklB-3if9A:
4.86
6bklC-3if9A:
4.86
6bklD-3if9A:
4.86