SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ifq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		5 / 10 ALA A 437
ASN A 398
LEU A 361
VAL A 369
ILE A 395
 None
 1.34A 1claA-3ifqA:
undetectable		 1claA-3ifqA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		4 / 5 THR A 331
THR A 330
GLU A 325
HIS A 360
 None
 1.43A 1d4fB-3ifqA:
undetectable		 1d4fB-3ifqA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4002_1
(SERUM ALBUMIN)		 3ifq E-CADHERIN
PLAKOGLOBIN
(Homo
sapiens;
Mus
musculus) 		3 / 3 PHE C 679
LEU C 676
SER A 380
 None
 0.75A 1e7aA-3ifqC:
undetectable		 1e7aA-3ifqC:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_B_FLPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		5 / 12 VAL A 523
ILE A 502
GLY A 565
ALA A 566
LEU A 570
 None
 1.02A 1eqhB-3ifqA:
undetectable		 1eqhB-3ifqA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		4 / 5 LEU A 389
VAL A 392
LEU A 396
GLN A 399
 None
 0.80A 1fbmE-3ifqA:
undetectable		 1fbmE-3ifqA:
8.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GEB_A_CAMA418_0
(CYTOCHROME P450-CAM)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		5 / 9 THR A 501
LEU A 488
ILE A 439
VAL A 476
ILE A 482
 None
 1.10A 1gebA-3ifqA:
undetectable		 1gebA-3ifqA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_1
(LIVER
CARBOXYLESTERASE I)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		5 / 12 VAL A 476
VAL A 523
LEU A 508
LEU A 518
LEU A 527
 None
 1.00A 1mx1E-3ifqA:
undetectable		 1mx1E-3ifqA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RV7_B_AB1B1001_1
(PROTEASE)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		5 / 11 ALA A 267
ILE A 222
LEU A 235
THR A 206
ALA A 246
 None
 1.19A 1rv7A-3ifqA:
undetectable
1rv7B-3ifqA:
undetectable		 1rv7A-3ifqA:
13.95
1rv7B-3ifqA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_A_NCAA1501_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3ifq PLAKOGLOBIN
E-CADHERIN
(Homo
sapiens;
Mus
musculus) 		4 / 7 ARG A 572
ALA C 670
ARG A 506
ASP C 665
 None
 1.13A 2e5dA-3ifqA:
undetectable
2e5dB-3ifqA:
undetectable		 2e5dA-3ifqA:
21.72
2e5dB-3ifqA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_B_NCAB1502_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3ifq PLAKOGLOBIN
E-CADHERIN
(Homo
sapiens;
Mus
musculus) 		4 / 7 ASP C 665
ARG A 572
ALA C 670
ARG A 506
 None
 1.13A 2e5dA-3ifqC:
undetectable
2e5dB-3ifqC:
undetectable		 2e5dA-3ifqC:
12.77
2e5dB-3ifqC:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA996_1
(GLUCOAMYLASE GLU1)		 3ifq E-CADHERIN
PLAKOGLOBIN
(Homo
sapiens;
Mus
musculus) 		4 / 7 ARG A 572
ASP C 665
THR A 564
GLY A 565
 None
 0.84A 2f6dA-3ifqA:
undetectable		 2f6dA-3ifqA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_CCSB417_0
(ESTROGEN RECEPTOR)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		3 / 3 GLN A 271
LYS A 272
VAL A 274
 None
 0.84A 2jfaB-3ifqA:
undetectable		 2jfaB-3ifqA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO5_A_CHDA131_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		5 / 12 ILE A 228
ILE A 306
LEU A 235
THR A 288
LEU A 254
 None
 1.21A 2qo5A-3ifqA:
undetectable		 2qo5A-3ifqA:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_B_X2NB1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		5 / 12 PRO A 483
ALA A 521
ALA A 445
ALA A 441
LEU A 459
 None
 1.28A 2x2nB-3ifqA:
undetectable		 2x2nB-3ifqA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 3ifq PLAKOGLOBIN
E-CADHERIN
(Homo
sapiens;
Mus
musculus) 		5 / 12 GLY A 640
ILE C 657
ASN C 660
VAL A 648
LEU A 634
 None
 1.14A 2zzmA-3ifqA:
undetectable		 2zzmA-3ifqA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_B_ADNB402_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 3ifq E-CADHERIN
PLAKOGLOBIN
(Homo
sapiens;
Mus
musculus) 		5 / 10 GLY A 640
ILE C 657
ASN C 660
VAL A 648
LEU A 634
 None
 1.16A 3ay0B-3ifqA:
undetectable		 3ay0B-3ifqA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		5 / 9 ALA A 437
ASN A 398
LEU A 361
VAL A 369
ILE A 395
 None
 1.36A 3claA-3ifqA:
undetectable		 3claA-3ifqA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC552_1
(GLUTAMATE
DEHYDROGENASE)		 3ifq E-CADHERIN
PLAKOGLOBIN
(Homo
sapiens;
Mus
musculus) 		3 / 3 TYR A 297
TYR C 681
GLY C 685
 SEP  C 684 ( 4.8A)
None
SEP  C 686 ( 2.4A)
 0.64A 3eteB-3ifqA:
undetectable
3eteD-3ifqA:
undetectable
3eteF-3ifqA:
undetectable		 3eteB-3ifqA:
23.56
3eteD-3ifqA:
23.56
3eteF-3ifqA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_D_MTXD164_2
(DIHYDROFOLATE
REDUCTASE)		 3ifq E-CADHERIN
PLAKOGLOBIN
(Homo
sapiens;
Mus
musculus) 		3 / 3 ARG C 714
ILE A 165
THR A 205
 None
 0.54A 3ia4D-3ifqC:
undetectable		 3ia4D-3ifqC:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_A_ADNA300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		5 / 11 ALA A 566
ILE A 505
GLY A 503
LEU A 527
LEU A 530
 None
 1.15A 3kw2A-3ifqA:
undetectable		 3kw2A-3ifqA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_B_ADNB300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		5 / 11 ALA A 566
ILE A 505
GLY A 503
LEU A 527
LEU A 530
 None
 1.21A 3kw2B-3ifqA:
undetectable		 3kw2B-3ifqA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA207_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		4 / 7 LEU A 373
ARG A 377
THR A 414
ALA A 411
 None
 1.33A 3mbgA-3ifqA:
undetectable
3mbgB-3ifqA:
undetectable		 3mbgA-3ifqA:
13.63
3mbgB-3ifqA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_A_CL6A506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		5 / 9 LEU A 497
LEU A 459
ILE A 485
ALA A 484
ALA A 455
 None
 1.13A 3mdvA-3ifqA:
undetectable		 3mdvA-3ifqA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_B_CL6B506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		6 / 12 LEU A 497
LEU A 459
ILE A 485
ALA A 484
ALA A 445
ALA A 455
 None
 1.33A 3mdvB-3ifqA:
undetectable		 3mdvB-3ifqA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Z_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		5 / 12 VAL A 523
LEU A 510
GLY A 565
ALA A 566
LEU A 570
 None
 0.92A 3n8zA-3ifqA:
undetectable		 3n8zA-3ifqA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_A_AICA375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		5 / 11 GLY A 358
LEU A 393
ASN A 425
SER A 391
LEU A 376
 None
 1.18A 3ndvA-3ifqA:
undetectable
3ndvB-3ifqA:
undetectable		 3ndvA-3ifqA:
21.23
3ndvB-3ifqA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_B_AICB376_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		5 / 11 LEU A 376
GLY A 358
LEU A 393
ASN A 425
SER A 391
 None
 1.18A 3ndvA-3ifqA:
undetectable
3ndvB-3ifqA:
undetectable		 3ndvA-3ifqA:
21.23
3ndvB-3ifqA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_C_AICC375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		5 / 11 GLY A 358
LEU A 393
ASN A 425
SER A 391
LEU A 376
 None
 1.16A 3ndvC-3ifqA:
undetectable
3ndvD-3ifqA:
undetectable		 3ndvC-3ifqA:
21.23
3ndvD-3ifqA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_D_AICD374_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		5 / 11 LEU A 376
GLY A 358
LEU A 393
ASN A 425
SER A 391
 None
 1.17A 3ndvC-3ifqA:
undetectable
3ndvD-3ifqA:
undetectable		 3ndvC-3ifqA:
21.23
3ndvD-3ifqA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_C_FLPC701_1
(CYCLOOXYGENASE-2)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		5 / 12 VAL A 523
LEU A 510
GLY A 565
ALA A 566
LEU A 570
 None
 0.99A 3pghC-3ifqA:
undetectable		 3pghC-3ifqA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SDR_A_210A822_1
(ALPHA-BISABOLENE
SYNTHASE)		 3ifq E-CADHERIN
PLAKOGLOBIN
(Homo
sapiens;
Mus
musculus) 		4 / 4 ASP A 449
ASP A 450
ARG C 630
ASP A 552
 None
 0.99A 3sdrA-3ifqA:
2.8		 3sdrA-3ifqA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SDV_A_911A822_0
(ALPHA-BISABOLENE
SYNTHASE)		 3ifq PLAKOGLOBIN
E-CADHERIN
(Homo
sapiens;
Mus
musculus) 		4 / 4 ASP A 449
ASP A 450
ARG C 630
ASP A 552
 None
 1.03A 3sdvA-3ifqA:
0.8		 3sdvA-3ifqA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VM4_A_IZPA1_1
(FATTY ACID
ALPHA-HYDROXYLASE)		 3ifq E-CADHERIN
PLAKOGLOBIN
(Homo
sapiens;
Mus
musculus) 		4 / 5 LEU C 677
ARG C 630
PRO A 496
ALA A 500
 None
 1.11A 3vm4A-3ifqC:
undetectable		 3vm4A-3ifqC:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_B_ACTB1358_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 3ifq PLAKOGLOBIN
E-CADHERIN
(Homo
sapiens;
Mus
musculus) 		4 / 7 PRO C 672
ARG A 506
GLY A 565
VAL A 603
 None
 0.99A 4a3uB-3ifqC:
undetectable		 4a3uB-3ifqC:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1477_0
(MJ0495-LIKE PROTEIN)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		4 / 6 THR A 564
GLY A 562
ILE A 559
LEU A 527
 None
 1.12A 4ac9C-3ifqA:
undetectable		 4ac9C-3ifqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		4 / 6 THR A 564
GLY A 562
ILE A 559
LEU A 527
 None
 1.10A 4acaC-3ifqA:
undetectable		 4acaC-3ifqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_B_BEZB1000_0
(BENZOATE-COENZYME A
LIGASE)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		5 / 9 ALA A 566
GLY A 565
ILE A 502
GLY A 503
ILE A 505
 None
 0.95A 4eatB-3ifqA:
undetectable		 4eatB-3ifqA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KHP_A_PARA1606_1
(16S RIBOSOMAL RNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		3 / 3 TYR A 245
ARG A 203
SER A 241
 None
 1.07A 4khpI-3ifqA:
undetectable
4khpJ-3ifqA:
undetectable		 4khpI-3ifqA:
12.22
4khpJ-3ifqA:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9I_B_8PRB601_1
(RHODOPSIN KINASE)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		5 / 8 GLY A 311
VAL A 316
ALA A 356
MET A 354
LEU A 379
 None
 1.16A 4l9iB-3ifqA:
2.2		 4l9iB-3ifqA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PB1_A_RBVA501_1
(NUPC FAMILY PROTEIN)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		5 / 12 GLY A 269
ALA A 267
ASN A 299
SER A 302
ILE A 305
 None
 1.01A 4pb1A-3ifqA:
undetectable		 4pb1A-3ifqA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		5 / 12 GLY A 269
ALA A 267
ASN A 299
SER A 302
ILE A 305
 None
 0.99A 4pd9A-3ifqA:
undetectable		 4pd9A-3ifqA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XOY_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		4 / 6 ALA A 314
GLN A 317
LEU A 315
LEU A 285
 None
 1.09A 4xoyA-3ifqA:
undetectable		 4xoyA-3ifqA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		5 / 12 ILE A 222
GLY A 218
HIS A 215
SER A 213
VAL A 190
 None
None
SO4  A 101 (-4.4A)
None
None
 1.15A 5n0oA-3ifqA:
undetectable		 5n0oA-3ifqA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		5 / 12 ILE A 222
GLY A 218
HIS A 215
SER A 213
VAL A 190
 None
None
SO4  A 101 (-4.4A)
None
None
 1.15A 5n0oB-3ifqA:
undetectable		 5n0oB-3ifqA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUJ_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		4 / 8 VAL A 607
LEU A 611
ILE A 524
VAL A 528
 None
 0.86A 5nujA-3ifqA:
undetectable		 5nujA-3ifqA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_A_ECLA1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		4 / 7 ILE A 247
LEU A 250
ILE A 306
ALA A 267
 None
 0.87A 6b5vA-3ifqA:
undetectable
6b5vC-3ifqA:
0.5		 6b5vA-3ifqA:
9.45
6b5vC-3ifqA:
9.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_B_ECLB1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		4 / 7 ALA A 296
ILE A 318
LEU A 315
ILE A 247
 None
 0.69A 6b5vA-3ifqA:
undetectable
6b5vB-3ifqA:
undetectable		 6b5vA-3ifqA:
9.45
6b5vB-3ifqA:
9.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_C_ECLC1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		4 / 7 ILE A 247
LEU A 250
ILE A 306
ALA A 267
 None
 0.86A 6b5vC-3ifqA:
0.5
6b5vD-3ifqA:
undetectable		 6b5vC-3ifqA:
9.45
6b5vD-3ifqA:
9.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_D_ECLD1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		4 / 7 ALA A 267
ILE A 247
LEU A 250
ILE A 306
 None
 0.88A 6b5vB-3ifqA:
undetectable
6b5vD-3ifqA:
undetectable		 6b5vB-3ifqA:
9.45
6b5vD-3ifqA:
9.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_D_GLYD713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 3ifq PLAKOGLOBIN
(Homo
sapiens) 		3 / 3 ARG A 506
HIS A 568
ARG A 572
 None
 1.09A 6dwdD-3ifqA:
undetectable		 6dwdD-3ifqA:
19.57