SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ifu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUI_B_AB1B100_1
(PROTEASE)		 3ifu NON-STRUCTURAL
PROTEIN
(Porcine
reproductive
and
respiratory
syndrome
virus) 		5 / 10 GLY A 154
ALA A 155
VAL A 158
PRO A 134
ILE A 131
 None
 0.96A 1muiA-3ifuA:
undetectable		 1muiA-3ifuA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPO_H_TESH1010_1
(ANTI-TESTOSTERONE
(HEAVY CHAIN)
ANTI-TESTOSTERONE
(LIGHT CHAIN))		 3ifu NON-STRUCTURAL
PROTEIN
(Porcine
reproductive
and
respiratory
syndrome
virus) 		5 / 12 SER A  79
SER A 148
TYR A 141
ALA A  19
GLY A  21
 None
 1.05A 1vpoH-3ifuA:
undetectable
1vpoL-3ifuA:
undetectable		 1vpoH-3ifuA:
19.73
1vpoL-3ifuA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OD9_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 3ifu NON-STRUCTURAL
PROTEIN
(Porcine
reproductive
and
respiratory
syndrome
virus) 		3 / 3 PHE A  94
PHE A  82
PHE A  17
 None
 0.81A 2od9A-3ifuA:
undetectable		 2od9A-3ifuA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQG_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 3ifu NON-STRUCTURAL
PROTEIN
(Porcine
reproductive
and
respiratory
syndrome
virus) 		3 / 3 PHE A  94
PHE A  82
PHE A  17
 None
 0.81A 2qqgA-3ifuA:
undetectable		 2qqgA-3ifuA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_2
(POL POLYPROTEIN)		 3ifu NON-STRUCTURAL
PROTEIN
(Porcine
reproductive
and
respiratory
syndrome
virus) 		5 / 9 GLY A 109
ALA A 108
ILE A  81
LEU A 116
VAL A 115
 None
 1.00A 3u7sB-3ifuA:
undetectable		 3u7sB-3ifuA:
22.16