SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ig2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3ig2 PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN
(Bacteroides
fragilis) 		4 / 6 TYR A 593
MET A 561
THR A 531
LEU A 530
 None
 1.06A 1v54A-3ig2A:
undetectable
1v54J-3ig2A:
undetectable		 1v54A-3ig2A:
19.33
1v54J-3ig2A:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ig2 PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN
(Bacteroides
fragilis) 		4 / 6 TYR A 593
MET A 561
THR A 531
LEU A 530
 None
 1.07A 2dyrA-3ig2A:
undetectable
2dyrJ-3ig2A:
undetectable		 2dyrA-3ig2A:
19.33
2dyrJ-3ig2A:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_J_CHDJ101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ig2 PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN
(Bacteroides
fragilis) 		4 / 6 TYR A 593
MET A 561
THR A 531
LEU A 530
 None
 1.05A 2dysA-3ig2A:
undetectable
2dysJ-3ig2A:
undetectable		 2dysA-3ig2A:
19.33
2dysJ-3ig2A:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_W_CHDW101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ig2 PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN
(Bacteroides
fragilis) 		4 / 6 TYR A 593
MET A 561
THR A 531
LEU A 530
 None
 1.05A 2dysN-3ig2A:
undetectable
2dysW-3ig2A:
undetectable		 2dysN-3ig2A:
19.33
2dysW-3ig2A:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3ig2 PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN
(Bacteroides
fragilis) 		4 / 5 TYR A 593
MET A 561
THR A 531
LEU A 530
 None
 1.08A 2eimJ-3ig2A:
undetectable		 2eimJ-3ig2A:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3ig2 PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN
(Bacteroides
fragilis) 		4 / 5 TYR A 593
MET A 561
THR A 531
LEU A 530
 None
 1.11A 2eimW-3ig2A:
undetectable		 2eimW-3ig2A:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8L_A_SAMA400_0
(HYPOTHETICAL PROTEIN
LMO1582)		 3ig2 PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN
(Bacteroides
fragilis) 		5 / 12 HIS A 614
ALA A 705
GLY A 616
LEU A 565
GLY A 686
 None
 1.10A 2f8lA-3ig2A:
undetectable		 2f8lA-3ig2A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ig2 PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN
(Bacteroides
fragilis) 		4 / 6 TYR A 593
MET A 561
THR A 531
LEU A 530
 None
 1.09A 2zxwA-3ig2A:
undetectable
2zxwJ-3ig2A:
undetectable		 2zxwA-3ig2A:
19.33
2zxwJ-3ig2A:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ig2 PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN
(Bacteroides
fragilis) 		4 / 6 TYR A 593
MET A 561
THR A 531
LEU A 530
 None
 1.05A 3abmA-3ig2A:
undetectable
3abmJ-3ig2A:
undetectable		 3abmA-3ig2A:
19.33
3abmJ-3ig2A:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 3ig2 PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN
(Bacteroides
fragilis) 		4 / 5 TYR A 593
MET A 561
THR A 531
LEU A 530
 None
 1.09A 3ag2J-3ig2A:
undetectable		 3ag2J-3ig2A:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 3ig2 PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN
(Bacteroides
fragilis) 		4 / 5 TYR A 593
MET A 561
THR A 531
LEU A 530
 None
 1.08A 3ag4J-3ig2A:
undetectable		 3ag4J-3ig2A:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3ig2 PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN
(Bacteroides
fragilis) 		4 / 6 TYR A 593
MET A 561
THR A 531
LEU A 530
 None
 1.07A 3asnA-3ig2A:
undetectable
3asnJ-3ig2A:
undetectable		 3asnA-3ig2A:
19.33
3asnJ-3ig2A:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3ig2 PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN
(Bacteroides
fragilis) 		4 / 6 TYR A 593
MET A 561
THR A 531
LEU A 530
 None
 1.08A 3asoA-3ig2A:
undetectable
3asoJ-3ig2A:
undetectable		 3asoA-3ig2A:
19.33
3asoJ-3ig2A:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y1D_D_DVAD5_0
(CYCLIC HEXAPEPTIDE
CYC[NDPOPPKID]
INTEGRASE)		 3ig2 PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN
(Bacteroides
fragilis) 		3 / 3 GLU A 645
LYS A 641
ASN A 646
 None
 0.99A 4y1dA-3ig2A:
undetectable
4y1dD-3ig2A:
undetectable		 4y1dA-3ig2A:
21.00
4y1dD-3ig2A:
2.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_A_0HKA1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 3ig2 PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN
(Bacteroides
fragilis) 		3 / 3 ASN A 527
LEU A 558
PHE A 567
 None
 0.64A 5dsgA-3ig2A:
undetectable		 5dsgA-3ig2A:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ig2 PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN
(Bacteroides
fragilis) 		4 / 5 TYR A 593
MET A 561
THR A 531
LEU A 530
 None
 1.06A 5wauJ-3ig2A:
undetectable		 5wauJ-3ig2A:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ig2 PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN
(Bacteroides
fragilis) 		4 / 5 TYR A 593
ARG A 562
MET A 561
THR A 531
 None
 1.26A 5x19J-3ig2A:
undetectable		 5x19J-3ig2A:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ig2 PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN
(Bacteroides
fragilis) 		4 / 5 TYR A 593
ARG A 562
MET A 561
THR A 531
 None
 1.17A 5x1bJ-3ig2A:
undetectable		 5x1bJ-3ig2A:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ig2 PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN
(Bacteroides
fragilis) 		4 / 5 TYR A 593
MET A 561
THR A 531
LEU A 530
 None
 1.10A 5z86J-3ig2A:
undetectable		 5z86J-3ig2A:
16.23