SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3igd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW4_A_TICA600_1
(CYTOCHROME P450 2B4)		 3igd ENDONUCLEASE PI-MTUI
(Mycobacterium
tuberculosis) 		5 / 11 ILE A  61
SER A 407
ALA A 433
VAL A  75
VAL A  93
 None
 0.96A 3kw4A-3igdA:
undetectable		 3kw4A-3igdA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3igd ENDONUCLEASE PI-MTUI
(Mycobacterium
tuberculosis) 		6 / 12 HIS A  17
PHE A   9
VAL A  31
ILE A  61
ALA A  65
VAL A 436
 None
 1.49A 5n0xA-3igdA:
undetectable		 5n0xA-3igdA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_A_HISA402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3igd ENDONUCLEASE PI-MTUI
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  58
LEU A  59
THR A   6
VAL A 438
ALA A 433
 None
 0.96A 6czmA-3igdA:
undetectable
6czmC-3igdA:
undetectable		 6czmA-3igdA:
16.76
6czmC-3igdA:
16.76