SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3igq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_1
(CATECHOL-O-METHYLTRA
NSFERASE)		 3igq GLR4197 PROTEIN
(Gloeobacter
violaceus) 		3 / 3 SER A 107
GLU A  82
ASP A  31
 None
 0.91A 2avdB-3igqA:
undetectable		 2avdB-3igqA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 3igq GLR4197 PROTEIN
(Gloeobacter
violaceus) 		4 / 6 LEU A  24
GLN A 193
ILE A 162
PHE A 165
 HG  A 700 ( 3.9A)
None
None
None
 0.97A 2jn3A-3igqA:
undetectable		 2jn3A-3igqA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOA_A_3TCA302_1
(DEOXYCYTIDINE KINASE)		 3igq GLR4197 PROTEIN
(Gloeobacter
violaceus) 		5 / 12 ILE A  76
GLU A 104
ALA A  41
ARG A  85
PHE A  78
 ACY  A 701 (-4.5A)
ACY  A 701 ( 4.8A)
None
ACY  A 701 ( 3.2A)
CL  A 901 (-4.7A)
 1.32A 2noaA-3igqA:
undetectable		 2noaA-3igqA:
20.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZZB_A_ACTA404_0
(PROTON-GATED ION
CHANNEL)		 3igq GLR4197 PROTEIN
(Gloeobacter
violaceus) 		4 / 4 LEU A  45
ILE A  73
ARG A  85
TYR A 102
 None
NA  A 801 ( 4.4A)
ACY  A 701 ( 3.2A)
ACY  A 701 ( 4.8A)
 0.22A 4zzbA-3igqA:
24.5		 4zzbA-3igqA:
68.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZZB_C_ACTC404_0
(PROTON-GATED ION
CHANNEL)		 3igq GLR4197 PROTEIN
(Gloeobacter
violaceus) 		4 / 4 ILE A  73
ILE A  76
ARG A  85
TYR A 102
 NA  A 801 ( 4.4A)
ACY  A 701 (-4.5A)
ACY  A 701 ( 3.2A)
ACY  A 701 ( 4.8A)
 0.40A 4zzbC-3igqA:
24.5		 4zzbC-3igqA:
68.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZZB_D_ACTD403_0
(PROTON-GATED ION
CHANNEL)		 3igq GLR4197 PROTEIN
(Gloeobacter
violaceus) 		4 / 4 ILE A  73
ARG A  85
TYR A 102
GLU A 104
 NA  A 801 ( 4.4A)
ACY  A 701 ( 3.2A)
ACY  A 701 ( 4.8A)
ACY  A 701 ( 4.8A)
 0.25A 4zzbD-3igqA:
24.7		 4zzbD-3igqA:
68.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZZB_E_ACTE403_0
(PROTON-GATED ION
CHANNEL)		 3igq GLR4197 PROTEIN
(Gloeobacter
violaceus) 		3 / 3 ARG A  85
TYR A 102
GLU A 104
 ACY  A 701 ( 3.2A)
ACY  A 701 ( 4.8A)
ACY  A 701 ( 4.8A)
 0.22A 4zzbE-3igqA:
24.3		 4zzbE-3igqA:
68.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZZC_A_ACTA406_0
(PROTON-GATED ION
CHANNEL)		 3igq GLR4197 PROTEIN
(Gloeobacter
violaceus) 		4 / 4 LEU A  45
ILE A  73
ARG A  85
TYR A 102
 None
NA  A 801 ( 4.4A)
ACY  A 701 ( 3.2A)
ACY  A 701 ( 4.8A)
 0.32A 4zzcA-3igqA:
24.5		 4zzcA-3igqA:
68.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZZC_B_ACTB406_0
(PROTON-GATED ION
CHANNEL)		 3igq GLR4197 PROTEIN
(Gloeobacter
violaceus) 		4 / 4 LEU A  45
ILE A  73
ARG A  85
TYR A 102
 None
NA  A 801 ( 4.4A)
ACY  A 701 ( 3.2A)
ACY  A 701 ( 4.8A)
 0.28A 4zzcB-3igqA:
24.3		 4zzcB-3igqA:
68.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZZC_C_ACTC407_0
(PROTON-GATED ION
CHANNEL)		 3igq GLR4197 PROTEIN
(Gloeobacter
violaceus) 		4 / 4 ILE A  73
ILE A  76
ARG A  85
TYR A 102
 NA  A 801 ( 4.4A)
ACY  A 701 (-4.5A)
ACY  A 701 ( 3.2A)
ACY  A 701 ( 4.8A)
 0.50A 4zzcC-3igqA:
24.6		 4zzcC-3igqA:
68.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZZC_D_ACTD406_0
(PROTON-GATED ION
CHANNEL)		 3igq GLR4197 PROTEIN
(Gloeobacter
violaceus) 		4 / 4 ILE A  73
ILE A  76
ARG A  85
TYR A 102
 NA  A 801 ( 4.4A)
ACY  A 701 (-4.5A)
ACY  A 701 ( 3.2A)
ACY  A 701 ( 4.8A)
 0.49A 4zzcD-3igqA:
24.4		 4zzcD-3igqA:
68.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZZC_E_ACTE406_0
(PROTON-GATED ION
CHANNEL)		 3igq GLR4197 PROTEIN
(Gloeobacter
violaceus) 		5 / 5 ILE A  73
ILE A  76
ARG A  85
TYR A 102
GLU A 104
 NA  A 801 ( 4.4A)
ACY  A 701 (-4.5A)
ACY  A 701 ( 3.2A)
ACY  A 701 ( 4.8A)
ACY  A 701 ( 4.8A)
 0.48A 4zzcE-3igqA:
24.6		 4zzcE-3igqA:
68.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_E_DVAE7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 3igq GLR4197 PROTEIN
(Gloeobacter
violaceus) 		3 / 3 TYR A 102
SER A  44
TRP A  47
 ACY  A 701 ( 4.8A)
None
None
 0.99A 5n8jB-3igqA:
undetectable		 5n8jB-3igqA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_O_DVAO7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 3igq GLR4197 PROTEIN
(Gloeobacter
violaceus) 		3 / 3 TYR A 102
SER A  44
TRP A  47
 ACY  A 701 ( 4.8A)
None
None
 0.97A 5n8jA-3igqA:
undetectable		 5n8jA-3igqA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_P_DVAP5_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 3igq GLR4197 PROTEIN
(Gloeobacter
violaceus) 		3 / 3 TYR A 102
SER A  44
TRP A  47
 ACY  A 701 ( 4.8A)
None
None
 1.00A 5n8jD-3igqA:
undetectable		 5n8jD-3igqA:
23.65