SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3igr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 3igr RIBOSOMAL-PROTEIN-S5
-ALANINE
N-ACETYLTRANSFERASE
(Aliivibrio
fischeri) 		4 / 8 LEU A  34
ARG A  29
SER A 144
MET A 113
 None
 1.18A 2qd2A-3igrA:
undetectable		 2qd2A-3igrA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X0Y_A_X0TA1625_1
(O-GLCNACASE NAGJ)		 3igr RIBOSOMAL-PROTEIN-S5
-ALANINE
N-ACETYLTRANSFERASE
(Aliivibrio
fischeri) 		5 / 12 TYR A  86
VAL A  84
TYR A 101
VAL A 147
ASN A 118
 None
None
None
None
NA  A 185 (-4.4A)
 1.33A 2x0yA-3igrA:
undetectable		 2x0yA-3igrA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YOE_C_FL7C1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3igr RIBOSOMAL-PROTEIN-S5
-ALANINE
N-ACETYLTRANSFERASE
(Aliivibrio
fischeri) 		4 / 8 GLY A  82
ILE A 121
VAL A   3
SER A 102
 None
 0.92A 2yoeB-3igrA:
undetectable
2yoeC-3igrA:
undetectable		 2yoeB-3igrA:
18.45
2yoeC-3igrA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA5_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 3igr RIBOSOMAL-PROTEIN-S5
-ALANINE
N-ACETYLTRANSFERASE
(Aliivibrio
fischeri) 		3 / 3 LYS A  75
SER A   4
GLN A  11
 None
 1.38A 3si7A-3igrA:
undetectable		 3si7A-3igrA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OU1_A_BEZA302_0
(RETRO-ALDOLASE,
DESIGN RA114)		 3igr RIBOSOMAL-PROTEIN-S5
-ALANINE
N-ACETYLTRANSFERASE
(Aliivibrio
fischeri) 		4 / 8 TYR A  86
ILE A 121
ILE A 133
ALA A 135
 None
 0.94A 4ou1A-3igrA:
undetectable		 4ou1A-3igrA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R82_A_ACTA205_0
(OXIDOREDUCTASE)		 3igr RIBOSOMAL-PROTEIN-S5
-ALANINE
N-ACETYLTRANSFERASE
(Aliivibrio
fischeri) 		4 / 5 GLY A 111
ARG A 115
GLU A   8
PHE A   7
 None
 1.25A 4r82A-3igrA:
undetectable
4r82B-3igrA:
undetectable		 4r82A-3igrA:
21.94
4r82B-3igrA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3igr RIBOSOMAL-PROTEIN-S5
-ALANINE
N-ACETYLTRANSFERASE
(Aliivibrio
fischeri) 		4 / 7 ILE A  89
ARG A 132
ILE A 133
MET A 124
 None
 0.93A 4xumA-3igrA:
undetectable		 4xumA-3igrA:
22.34