SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ihm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_A_TESA325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 3ihm STYRENE
MONOOXYGENASE A
(Pseudomonas
putida) 		4 / 7 LEU A 243
HIS A 247
THR A 226
ASN A 214
 None
 1.26A 1afsA-3ihmA:
undetectable		 1afsA-3ihmA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_B_TESB325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 3ihm STYRENE
MONOOXYGENASE A
(Pseudomonas
putida) 		4 / 7 LEU A 243
HIS A 247
THR A 226
ASN A 214
 None
 1.26A 1afsB-3ihmA:
undetectable		 1afsB-3ihmA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 3ihm STYRENE
MONOOXYGENASE A
(Pseudomonas
putida) 		5 / 11 HIS A  50
VAL A  63
LEU A  19
LEU A  15
THR A  12
 None
 1.13A 1dmyA-3ihmA:
undetectable		 1dmyA-3ihmA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXV_B_PNNB1001_0
(PENICILLIN ACYLASE)		 3ihm STYRENE
MONOOXYGENASE A
(Pseudomonas
putida) 		4 / 7 SER A 375
PHE A 409
ALA A 379
PHE A  88
 None
 1.24A 1fxvA-3ihmA:
undetectable
1fxvB-3ihmA:
undetectable		 1fxvA-3ihmA:
20.47
1fxvB-3ihmA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3ihm STYRENE
MONOOXYGENASE A
(Pseudomonas
putida) 		5 / 10 ARG A  57
SER A 312
ALA A 311
ALA A 308
THR A  54
 None
 1.10A 1gtnB-3ihmA:
undetectable
1gtnC-3ihmA:
undetectable		 1gtnB-3ihmA:
9.65
1gtnC-3ihmA:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3ihm STYRENE
MONOOXYGENASE A
(Pseudomonas
putida) 		5 / 10 ARG A  57
SER A 312
ALA A 311
ALA A 308
THR A  54
 None
 1.13A 1gtnH-3ihmA:
undetectable
1gtnI-3ihmA:
undetectable		 1gtnH-3ihmA:
9.65
1gtnI-3ihmA:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 3ihm STYRENE
MONOOXYGENASE A
(Pseudomonas
putida) 		5 / 12 TYR A  39
GLY A   9
ALA A  10
GLY A  18
LEU A 112
 None
 1.07A 1igxA-3ihmA:
undetectable		 1igxA-3ihmA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_0
(AMINOMETHYLTRANSFERA
SE)		 3ihm STYRENE
MONOOXYGENASE A
(Pseudomonas
putida) 		5 / 12 THR A 185
ILE A 196
VAL A 211
ASN A 214
LEU A 358
 None
 1.25A 1wsvA-3ihmA:
undetectable		 1wsvA-3ihmA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_B_THHB4001_0
(AMINOMETHYLTRANSFERA
SE)		 3ihm STYRENE
MONOOXYGENASE A
(Pseudomonas
putida) 		5 / 12 THR A 185
ILE A 196
VAL A 211
ASN A 214
LEU A 358
 None
 1.30A 1wsvB-3ihmA:
undetectable		 1wsvB-3ihmA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDM_B_AGGB1462_1
(INTEGRIN ALPHA-IIB
INTEGRIN BETA-3)		 3ihm STYRENE
MONOOXYGENASE A
(Pseudomonas
putida) 		5 / 12 TYR A 101
LEU A  44
SER A  96
ASN A 309
ALA A  49
 None
 1.25A 2vdmA-3ihmA:
undetectable
2vdmB-3ihmA:
undetectable		 2vdmA-3ihmA:
23.09
2vdmB-3ihmA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3ihm STYRENE
MONOOXYGENASE A
(Pseudomonas
putida) 		4 / 8 SER A 359
VAL A 303
PHE A 161
ASN A 352
 None
 1.23A 2wekA-3ihmA:
undetectable		 2wekA-3ihmA:
24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3ihm STYRENE
MONOOXYGENASE A
(Pseudomonas
putida) 		4 / 8 SER A 359
VAL A 303
PHE A 161
ASN A 352
 None
 1.21A 2wekB-3ihmA:
undetectable		 2wekB-3ihmA:
24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM9_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3ihm STYRENE
MONOOXYGENASE A
(Pseudomonas
putida) 		5 / 9 ALA A  10
TYR A  39
GLY A  11
TYR A 101
HIS A  50
 None
 1.42A 2zm9A-3ihmA:
0.0		 2zm9A-3ihmA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP9_D_SPMD230_1
(LS-24)		 3ihm STYRENE
MONOOXYGENASE A
(Pseudomonas
putida) 		3 / 3 GLU A  69
GLU A  58
ASN A  64
 None
 0.62A 3lp9B-3ihmA:
undetectable
3lp9D-3ihmA:
undetectable		 3lp9B-3ihmA:
16.71
3lp9D-3ihmA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_A_NCAA302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 3ihm STYRENE
MONOOXYGENASE A
(Pseudomonas
putida) 		4 / 8 LEU A  44
ASP A 267
SER A 207
SER A 202
 None
 1.01A 3rodA-3ihmA:
undetectable		 3rodA-3ihmA:
25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 3ihm STYRENE
MONOOXYGENASE A
(Pseudomonas
putida) 		4 / 6 HIS A  50
HIS A  16
SER A 312
ASP A 384
 None
 1.19A 4blvA-3ihmA:
2.2		 4blvA-3ihmA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L3G_F_ACTF401_0
(METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN)		 3ihm STYRENE
MONOOXYGENASE A
(Pseudomonas
putida) 		3 / 3 ARG A 340
LEU A 318
GLU A 321
 None
 0.72A 4l3gF-3ihmA:
undetectable		 4l3gF-3ihmA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA205_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 3ihm STYRENE
MONOOXYGENASE A
(Pseudomonas
putida) 		5 / 12 TYR A 388
MET A 310
ARG A  57
ASN A 387
ALA A  52
 None
 1.50A 4oadA-3ihmA:
undetectable		 4oadA-3ihmA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_1
(ANDROGEN RECEPTOR)		 3ihm STYRENE
MONOOXYGENASE A
(Pseudomonas
putida) 		5 / 12 LEU A 261
LEU A 240
MET A 239
ILE A 176
VAL A 250
 None
 1.14A 4ok1A-3ihmA:
undetectable		 4ok1A-3ihmA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_B_ACTB404_0
(D-ALANINE--D-ALANINE
LIGASE)		 3ihm STYRENE
MONOOXYGENASE A
(Pseudomonas
putida) 		4 / 7 ARG A 340
GLY A 280
SER A 333
LEU A 336
 None
 1.05A 5bphB-3ihmA:
undetectable		 5bphB-3ihmA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_D_ACTD403_0
(D-ALANINE--D-ALANINE
LIGASE)		 3ihm STYRENE
MONOOXYGENASE A
(Pseudomonas
putida) 		4 / 6 ARG A 340
GLY A 280
SER A 333
LEU A 336
 None
 1.11A 5bphD-3ihmA:
2.2		 5bphD-3ihmA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3ihm STYRENE
MONOOXYGENASE A
(Pseudomonas
putida) 		4 / 5 THR A 283
ALA A 282
THR A 289
HIS A 281
 None
 1.30A 5ecmA-3ihmA:
undetectable		 5ecmA-3ihmA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ihm STYRENE
MONOOXYGENASE A
(Pseudomonas
putida) 		5 / 12 ARG A  57
SER A 312
ALA A 311
ALA A 308
THR A  54
 None
 1.14A 5eeuI-3ihmA:
undetectable
5eeuJ-3ihmA:
undetectable		 5eeuI-3ihmA:
9.65
5eeuJ-3ihmA:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ihm STYRENE
MONOOXYGENASE A
(Pseudomonas
putida) 		5 / 12 ARG A  57
SER A 312
ALA A 311
ALA A 308
THR A  54
 None
 1.14A 5eevI-3ihmA:
undetectable
5eevJ-3ihmA:
undetectable		 5eevI-3ihmA:
9.65
5eevJ-3ihmA:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ihm STYRENE
MONOOXYGENASE A
(Pseudomonas
putida) 		5 / 12 ARG A  57
SER A 312
ALA A 311
ALA A 308
THR A  54
 None
 1.14A 5eewI-3ihmA:
undetectable
5eewJ-3ihmA:
undetectable		 5eewI-3ihmA:
9.65
5eewJ-3ihmA:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 3ihm STYRENE
MONOOXYGENASE A
(Pseudomonas
putida) 		5 / 12 ASP A  27
VAL A  28
THR A  29
ALA A 111
LEU A 112
 None
 1.05A 5kocA-3ihmA:
undetectable		 5kocA-3ihmA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM2_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 3ihm STYRENE
MONOOXYGENASE A
(Pseudomonas
putida) 		5 / 9 VAL A 140
LEU A  17
ALA A  13
VAL A  28
ILE A   5
 None
 1.15A 5om2A-3ihmA:
undetectable
5om2B-3ihmA:
undetectable		 5om2A-3ihmA:
13.90
5om2B-3ihmA:
6.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3ihm STYRENE
MONOOXYGENASE A
(Pseudomonas
putida) 		3 / 3 SER A 312
HIS A  50
TYR A 104
 None
 0.75A 5y2tA-3ihmA:
undetectable		 5y2tA-3ihmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8F_A_ACTA803_0
(UNCHARACTERIZED
PROTEIN)		 3ihm STYRENE
MONOOXYGENASE A
(Pseudomonas
putida) 		3 / 3 GLU A  58
LEU A  61
ARG A 115
 None
 0.77A 6d8fA-3ihmA:
undetectable		 6d8fA-3ihmA:
21.92