SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ihs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BPX_A_SALA257_1
(TRANSCRIPTIONAL
REGULATOR)		 3ihs PHOSPHOCARRIER
PROTEIN HPR
(Bacillus
anthracis) 		4 / 8 ALA A  70
PHE A  29
ILE A  33
THR A  65
 None
 0.91A 3bpxA-3ihsA:
undetectable
3bpxB-3ihsA:
undetectable		 3bpxA-3ihsA:
19.33
3bpxB-3ihsA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 3ihs PHOSPHOCARRIER
PROTEIN HPR
(Bacillus
anthracis) 		5 / 12 GLY A  58
GLY A  56
GLY A  13
ASN A  12
SER A  59
 None
 0.88A 4uciA-3ihsA:
undetectable		 4uciA-3ihsA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 3ihs PHOSPHOCARRIER
PROTEIN HPR
(Bacillus
anthracis) 		5 / 12 GLY A  58
GLY A  56
GLY A  13
ASN A  12
SER A  59
 None
 0.88A 4uciB-3ihsA:
undetectable		 4uciB-3ihsA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 3ihs PHOSPHOCARRIER
PROTEIN HPR
(Bacillus
anthracis) 		5 / 12 GLY A  58
GLY A  56
GLY A  13
ASN A  12
SER A  59
 None
 0.86A 4uckA-3ihsA:
undetectable		 4uckA-3ihsA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_A_SALA801_1
(PROTEIN POLYBROMO-1)		 3ihs PHOSPHOCARRIER
PROTEIN HPR
(Bacillus
anthracis) 		4 / 7 ILE A  55
LEU A  10
TYR A  80
ALA A  19
 None
 0.87A 4y03A-3ihsA:
undetectable		 4y03A-3ihsA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_B_SALB801_1
(PROTEIN POLYBROMO-1)		 3ihs PHOSPHOCARRIER
PROTEIN HPR
(Bacillus
anthracis) 		4 / 5 LEU A  10
TYR A  80
ALA A  19
ILE A  50
 None
 1.01A 4y03B-3ihsA:
1.7		 4y03B-3ihsA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 3ihs PHOSPHOCARRIER
PROTEIN HPR
(Bacillus
anthracis) 		4 / 8 ILE A  61
THR A  62
THR A  65
GLU A  71
 None
 1.10A 6c06C-3ihsA:
undetectable		 6c06C-3ihsA:
undetectable